• Department of Anesthesiology, People’s Hospital of Zhongshan City, Zhongshan, Guangzhou 528403, P. R. China;
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目的  通过Narcotrend指导丙泊酚的靶控浓度来研究帕瑞昔布钠超前镇痛对宫腔手术患者术中和术后镇痛效果的影响。 方法  2012年1月-6月,60例实施宫腔手术的患者随机分为A、B两组,每组30例,A组为术前20 min静脉注射帕瑞昔布钠组,B组为术前20 min静脉注射等量生理盐水组。记录Narcotrend值D1,患者心率稳定时两组的靶控浓度、血压、心率、血氧饱和度(SpO2)及患者术苏醒后10 min镇痛效果视觉模拟评分(VAS)、Riker镇静、躁动评分(SAS)。 结果  A组患者的瑞芬太尼目标靶控浓度小于B组(P<0.05),两组的丙泊酚靶控浓度差异无统计学意义(P>0.05)。两组患者血压、心率均小于术前(P<0.05),SpO2与术前比较差异无统计学意义(P>0.05)。术后患者VAS评分A组低于B组(P<0.05),SAS评分B组高于A组(P<0.05)。 结论  帕瑞昔布钠对Narcotrend值无影响,帕瑞昔布钠能减少宫腔手术患者术中、术后的疼痛及术后的躁动。

Citation: LIAO Xiaozu,LI Binfei,CHENG Zhou,ZHANG Zhigang,WEN Jing.. Application of Parecoxib Sodium Preemptive Analgesia Combined with Narcotrend on Patients with Uterine Cavity Surgery. West China Medical Journal, 2013, 28(8): 1222-1224. doi: 10.7507/1002-0179.20130381 Copy

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