• 1. Department of Respiratory Medicine;the First People's Hospital of Yibin, Yibin, Sichuan 644000, P. R. China;
  • 2. Nosocomial Infection Management Office;the First People's Hospital of Yibin, Yibin, Sichuan 644000, P. R. China;
  • 3. Department of Respiratory Medicine, the Second People's Hospital of Yibin, Yibin, Sichuan 644000, P. R. China;
ChenLiping, Email: 1837639492@qq.com
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Objective To understand the clinical distribution and drug resistance of Klebsiella pneumoniae in Yibin during 2011 to 2014 so as to provide evidence for clinical rational use of antimicrobial drugs. Methods Klebsiella pneumoniae isolated from all types of clinical specimens were collected from the First People's Hospital and the Second People's Hospital of Yibin during 2011 to 2014. VITEK2 Compact and its supporting identification card GP and drug sensitivity test card AST-GP67 were used for detection, and the results were analyzed and summarized. Results Most Klebsiella pneumoniae were detected from the Department of Respiratory Medicine, the proportion for each year was 48.15%, 46.24%, 45.44%, and 44.97% during 2011 to 2014. Klebsiella pneumoniae isolated were mainly from sputum samples, the proportion for each year was 81.01%, 89.18%, 87.80%, and 83.52% between 2011 and 2014. Imipenem and piperacillin/tazobactam resistance rates were lower, but the overall trend was rising. Ampicillin/sulbactam, and sulfamethoxazole resistance rates were higher. Levofloxacin, ciprofloxacin increased year by year. Aztreonam, cefepime, and amikacin rate declined. Conclusion Klebsiella pneumoniae is one of the main infection pathogen in the Department of Respiratory Medicine. Klebsiella pneumoniae resistance rates are higher. Klebsiella pneumoniae were sensitive to enzyme inhibitors β-lactam antimicrobial agents and carbapenem antibiotics.

Citation: LuoLinjie, TangFengming, ChenLiping, GuoYanni. Clinical Distribution and Drug Resistance of Klebsiella Pneumoniae in Yibin Region from 2011 to 2014. West China Medical Journal, 2016, 31(3): 414-417. doi: 10.7507/1002-0179.201600113 Copy

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