New progress of clinical orthopedic rehabilitation_West China Medical Journal

Authors：

 ZHOU Mouwang

Department of Rehabilitation, Peking University Third Hospital, Beijing 100191, P. R. China;

Corresponding author：

ZHOU Mouwang, Email: zhoumouwang@163.com

Keywords：

Orthopedic rehabilitation; Working mode; Stem cells; Platelet-rich plasma

DOI：

10.7507/1002-0179.201808006

Video：

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This paper describes the latest definition, connotation, content and working mode of orthopedic rehabilitation. It points out that the main contents of orthopedic rehabilitation should include the rehabilitation of patients with orthopedic diseases after surgery and non-surgical treatment. The research progress of stem cells, especially mesenchymal stem cells, in the treatment of osteoarthritis and lumbar intervertebral disc degeneration are reviewed. The latest progress of platelet-rich plasma in the treatment of injury of articular cartilage, ligament and tendon injuries are also reviewed.

Citation： ZHOU Mouwang. New progress of clinical orthopedic rehabilitation. West China Medical Journal, 2018, 33(10): 1197-1200. doi: 10.7507/1002-0179.201808006 Copy

1.	Yim RL, Lee JT, Bow CH, et al. A systematic review of the safety and efficacy of mesenchymal stem cells for disc degeneration: insights and future directions for regenerative therapeutics. Stem Cells Dev J, 2014, 23(21): 2553-2567.
2.	刘京宇, 周谋望, 侯树勋, 等. 腰椎退行性疾病术后康复模式研究. 中国骨与关节杂志, 2016, 5(3): 183-187.
3.	马驰, 吴新宝, 侯树勋, 等. 腰椎单节段固定融合术后12周不同康复模式与术后症状改善的相关性研究. 中国骨与关节杂志, 2016, 5(3): 164-169.
4.	李涛, 周谋望, 侯树勋, 等. 膝关节骨折患者康复模式的前瞻性多中心研究. 中国骨与关节杂志, 2016, 5(3): 199-204.
5.	石秀秀, 秦江, 唐金树, 等. 全程系统康复对老年患者单节段腰椎融合术后功能的影响. 中国疼痛医学杂志, 2016(9): 672-676.
6.	李涛, 周谋望, 侯树勋, 等. 肘关节骨折患者康复模式的前瞻性多中心研究. 中国骨与关节杂志, 2016, 5(4): 199-204.
7.	Glenn JD, Whartenby KA. Mesenchymal stem cells: emerging mechanisms of immunomodulation and therapy. World J Stem Cells, 2014, 6(5): 526-539.
8.	Centeno CJ, Busse D, Kisiday J, et al. Increased knee cartilage volume in degenerative joint disease using percutaneously implanted, autologous mesenchymal stem cells. Pain Physician, 2008, 11(3): 343-353.
9.	Orozco L, Munar A, Soler R, et al. Treatment of knee osteoarthritis with autologous mesenchymal stem cells: a pilot study. Transplantation, 2013, 95(12): 1535-1541.
10.	Orozco L, Soler R, Morera C, et al. Intervertebral disc repair by autologous mesenchymal bone marrow cells: a pilot study. Transplantation, 2011, 92(7): 822-828.
11.	Pettine KA, Suzuki R, Sand T, et al. Treatment of discogenic back pain with autologous bone marrow concentrate injection with minimum two year follow up. Int Orthop, 2016, 40(1): 135-140.
12.	Pettine KA, Murphy MB, Suzuki RK, et al. Percutaneous injection of autologous bone marrow concentrate cells significantly reduces lumbar discogenic pain through 12 months. Stem Cells, 2015, 33(1): 146-156.
13.	Moyer R, Ikert K, Long K, et al. The value of preoperative exercise and education for patients undergoing total hip and knee arthroplasty: a systematic review and meta-analysis. JBJS Rev, 2017, 5(12): e2.
14.	Cugat R, Carrillo JM, Serra I, et al. Articular cartilage defects reconstruction by plasma rich in growth factors. Bologna: Timeo Ed, 2006: 801-807.
15.	Sánchez M, Azofra J, Anitua E, et al. Plasma rich in growth factors to treat an articular cartilage avulsion: a case report. Med Sci Sports Exerc, 2003, 35(10): 1648-1652.
16.	李明. 关节内注射富血小板血浆对膝关节软骨退行性变的治疗作用. 中国修复重建外科杂志, 2011, 25(10): 1192-1196.
17.	Anitua E, Andía I, Sanchez M, et al. Autologous preparations rich in growth factors promote proliferation and induce VEGF and HGF production by human tendon cells in culture. J Orthop Res, 2005, 23(2): 281-286.
18.	Mishra A, Pavelko T. Treatment of chronic elbow tendinosis with buffered platelet-rich plasma. Am J Sports Med, 2006, 34(11): 1774-1778.
19.	Wasterlain AS, Braun HJ, Harris AH, et al. The systemic effects of Platelet-Rich plasma injection. Am J Sports Med, 2013, 41(1): 186-193.
20.	Yuan T, Zhang CQ, Wang JH. Augmenting tendon and ligament repair with platelet-rich plasma (PRP). Muscles Ligaments Tendons J, 2013, 3(3): 139-149.

1. Yim RL, Lee JT, Bow CH, et al. A systematic review of the safety and efficacy of mesenchymal stem cells for disc degeneration: insights and future directions for regenerative therapeutics. Stem Cells Dev J, 2014, 23(21): 2553-2567.
2. 刘京宇, 周谋望, 侯树勋, 等. 腰椎退行性疾病术后康复模式研究. 中国骨与关节杂志, 2016, 5(3): 183-187.
3. 马驰, 吴新宝, 侯树勋, 等. 腰椎单节段固定融合术后12周不同康复模式与术后症状改善的相关性研究. 中国骨与关节杂志, 2016, 5(3): 164-169.
4. 李涛, 周谋望, 侯树勋, 等. 膝关节骨折患者康复模式的前瞻性多中心研究. 中国骨与关节杂志, 2016, 5(3): 199-204.
5. 石秀秀, 秦江, 唐金树, 等. 全程系统康复对老年患者单节段腰椎融合术后功能的影响. 中国疼痛医学杂志, 2016(9): 672-676.
6. 李涛, 周谋望, 侯树勋, 等. 肘关节骨折患者康复模式的前瞻性多中心研究. 中国骨与关节杂志, 2016, 5(4): 199-204.
7. Glenn JD, Whartenby KA. Mesenchymal stem cells: emerging mechanisms of immunomodulation and therapy. World J Stem Cells, 2014, 6(5): 526-539.
8. Centeno CJ, Busse D, Kisiday J, et al. Increased knee cartilage volume in degenerative joint disease using percutaneously implanted, autologous mesenchymal stem cells. Pain Physician, 2008, 11(3): 343-353.
9. Orozco L, Munar A, Soler R, et al. Treatment of knee osteoarthritis with autologous mesenchymal stem cells: a pilot study. Transplantation, 2013, 95(12): 1535-1541.
10. Orozco L, Soler R, Morera C, et al. Intervertebral disc repair by autologous mesenchymal bone marrow cells: a pilot study. Transplantation, 2011, 92(7): 822-828.
11. Pettine KA, Suzuki R, Sand T, et al. Treatment of discogenic back pain with autologous bone marrow concentrate injection with minimum two year follow up. Int Orthop, 2016, 40(1): 135-140.
12. Pettine KA, Murphy MB, Suzuki RK, et al. Percutaneous injection of autologous bone marrow concentrate cells significantly reduces lumbar discogenic pain through 12 months. Stem Cells, 2015, 33(1): 146-156.
13. Moyer R, Ikert K, Long K, et al. The value of preoperative exercise and education for patients undergoing total hip and knee arthroplasty: a systematic review and meta-analysis. JBJS Rev, 2017, 5(12): e2.
14. Cugat R, Carrillo JM, Serra I, et al. Articular cartilage defects reconstruction by plasma rich in growth factors. Bologna: Timeo Ed, 2006: 801-807.
15. Sánchez M, Azofra J, Anitua E, et al. Plasma rich in growth factors to treat an articular cartilage avulsion: a case report. Med Sci Sports Exerc, 2003, 35(10): 1648-1652.
16. 李明. 关节内注射富血小板血浆对膝关节软骨退行性变的治疗作用. 中国修复重建外科杂志, 2011, 25(10): 1192-1196.
17. Anitua E, Andía I, Sanchez M, et al. Autologous preparations rich in growth factors promote proliferation and induce VEGF and HGF production by human tendon cells in culture. J Orthop Res, 2005, 23(2): 281-286.
18. Mishra A, Pavelko T. Treatment of chronic elbow tendinosis with buffered platelet-rich plasma. Am J Sports Med, 2006, 34(11): 1774-1778.
19. Wasterlain AS, Braun HJ, Harris AH, et al. The systemic effects of Platelet-Rich plasma injection. Am J Sports Med, 2013, 41(1): 186-193.
20. Yuan T, Zhang CQ, Wang JH. Augmenting tendon and ligament repair with platelet-rich plasma (PRP). Muscles Ligaments Tendons J, 2013, 3(3): 139-149.

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