Study on the economic burden of healthcare-associated infections in Sichuan Province_West China Medical Journal

Authors：

LI Ying ¹ , CHEN Lan ² , XIAO Weijun ¹ , LU Shijunbo ³ ,  XIANG Qian ⁴

1. Department of Healthcare-associated Infection Control, Liangshan First People’s Hospital, Xichang, Sichuan 615000, P. R. China;
2. Department of Food Physics and Chemistry, Chengdu Food and Drug Inspection Institute, Chengdu, Sichuan 610045, P. R. China;
3. College of Integrated Traditional Chinese and Western Medicine, Southwest Medical University, Luzhou, Sichuan 646000, P. R. China;
4. Healthcare-associated Infection Control Center, Sichuan Academy of Medical Sciences and Sichuan Provincial People’s Hospital, Chengdu, Sichuan 610072, P. R. China;

Corresponding author：

XIANG Qian, Email: 3all@163.com

Keywords：

Healthcare-associated infections; Economic burden; Nested case-control study

DOI：

10.7507/1002-0179.202001117

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Abstract Full text Figures/Tables Video References Cited by

Objective To measure and evaluate the economic burden of hospital infection in Sichuan, and provide a basis for targeted economic evaluation of healthcare-associated infection (HAI).Methods In hospitals participating in the 2016 Sichuan provincial prevalence survey of HAI, matched cases were used to extract cases and controls, and then a multi-center nested case-control study was conducted.Results A total of 225 pairs/450 patients were selected in 51 hospitals, and 175 pairs/350 patients were successfully matched. The median of the difference of hospitalization costs between matched-pairs were RMB 3 362.0, and the difference was statistically significant (Z=3.275, P<0.001).Conclusions The hospitalization costs caused by HAI should be given special attention in the current medical insurance reform. Efforts need to be taken to reduce the hospitalization costs caused by HAI.

Citation： LI Ying, CHEN Lan, XIAO Weijun, LU Shijunbo, XIANG Qian. Study on the economic burden of healthcare-associated infections in Sichuan Province. West China Medical Journal, 2020, 35(8): 954-957. doi: 10.7507/1002-0179.202001117 Copy

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1. Allegranzi B, Bagheri Nejad S, Combescure C, <italic>et al</italic>. Burden of endemic health-care-associated infection in developing countries: systematic review and meta-analysis. Lancet, 2011, 377(9761): 228-241.
2. Gabriel L, Beriot-Mathiot A. Hospitalization stay and costs attributable to Clostridium difficile infection: a critical review. J Hosp Infect, 2014, 88(1): 12-21.
3. 国畅, 刘永华, 田丹生. 住院患者医院感染直接经济损失的统计与分析. 中华医院感染学杂志, 2012, 22(8): 1651-1653.
4. Vrijens F, Hulstaert F, Van De Sande S, <italic>et al</italic>. Hospital-acquired, laboratory-confirmed bloodstream infections: linking National surveillance data to clinical and financial hospital data to estimate increased length of stay and healthcare costs. J Hosp Infect, 2010, 75(3): 158-162.
5. 四川省医院感染质量控制中心. 2016年四川省医院感染横断面调查报告. (2017-06-26) [ 2020-01-10]. http://www.scnicn.com:8081/zhuzhan/middlenews/20170626/812.shtml.
6. 中华人民共和国国家卫生健康委员会. 关于印发医院感染诊断标准(试行)的通知. (2001-11-07) [2020-01-10]. http://www.nhc.gov.cn/yzygj/s3593/200804/e19e4448378643a09913ccf2a055c79d.shtml.
7. 中华人民共和国卫生部. 医院感染监测规范: WS/T 312—2009, 2009.
8. 四川省统计局, 国家统计局四川调查总队. 四川统计年鉴-2016. 中国统计出版社, 2017.
9. Vasudevan A, Memon BI, Mukhopadhyay A, <italic>et al</italic>. The costs of nosocomial resistant gram negative intensive care unit infections among patients with the systemic inflammatory response syndrome- a propensity matched case control study. Antimicrob Resist Infect Control, 2015, 4(1): 3.
10. Stewardson AJ, Allignol A, Beyersmann J, <italic>et al</italic>. The health and economic burden of bloodstream infections caused by antimicrobial-susceptible and non-susceptible Enterobacteriaceae and Staphylococcus aureus in European hospitals, 2010 and 2011: a multicentre retrospective cohort study. Euro Surveill, 2016, 21(33).
11. Eva Morales, Francesc Cots, Maria Sala, <italic>et al</italic>. Hospital costs of nosocomial multi-drug resistant <italic>Pseudomonas aeruginosa</italic> acquisition. BMC Health Serv Res, 2012, 12: 122.
12. 周春莲, 陈惠清, 邓明卓. 某三级医院住院患者医院感染直接经济损失及控制策略研究. 中华医院感染学杂志, 2014, 24(21): 5396-5398, 5431.
13. 四川省人民政府. 四川省人民政府办公厅关于印发进一步深化基本医疗保险支付方式改革实施方案的通知. (2018-01-08) [2020-01-10]. http://www.sc.gov.cn/10462/12771/2018/1/8/10442346.shtml.
14. Stone PW, Glied S, Mcnair PD, <italic>et al</italic>. CMS changes in reimbursement for HAIs: setting a research agenda. Med Care, 2010, 48(5): 433-439.
15. 付强, 郭燕红. 新时期国家医院感染管理战略探讨. 中华医院感染学杂志, 2013, 23(20): 4861-4864.

West China Medical Journal

Study on the economic burden of healthcare-associated infections in Sichuan Province

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