DENG Gao 1 , WU Pengyu 2 , QIN Haizhi 1 , XI Heng 3 , WANG Xinxin 1 , CHEN Min 1
  • 1. Department of Traditional Chinese Medicine, The Third People’s Hospital of Chengdu, AffiliatedHospital of Southwest Jiaotong University & The Second Affiliated Hospital of Chengdu, Chongqing Medical University, Chengdu 610014, P. R. China;
  • 2. Department of Gastroenterology, The Third People’s Hospital of Chengdu, AffiliatedHospital of Southwest Jiaotong University & The Second Affiliated Hospital of Chengdu, Chongqing Medical University, Chengdu 610014, P. R. China;
  • 3. Department of Pharmacy, The Third People’s Hospital of Chengdu, AffiliatedHospital of Southwest Jiaotong University & The Second Affiliated Hospital of Chengdu, Chongqing Medical University, Chengdu 610014, P. R. China;
CHEN Min, Email: 150325684@qq.com
non-severe acute pancreatitis; Yidantong recipe; Jinhuang powder external application therapy; promoting blood circulation and resolving blood stasis; retrospective cohort study
10.7507/1007-9424.202401049
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Objective To determine the effectiveness of Yidantong recipe retained enema combined with external application of Jinhuang powder on non-severe acute pancreatitis (NSAP). Methods A total of 134 patients with NSAP, admitted to the Third People’s Hospital of Chengdu from September 2019 to August 2022 were included in this retrospective cohort study. All patients received routine Western medicine treatment, and they were divided into a observation group (n=66) and a control group (n=68) based on whether they underwent treatment of Yidantong recipe retained enema combined with external application of Jinhuang powder. The variables including incidence of adverse clinical outcome events, severity scores after treatment, the recovery time of flatus and bowel movement, duration of fasting food and water, scores of traditional Chinese medicine (TCM) syndromes and numerical value of blood indices before and after treatment, and the treatment effect of the two groups were statistically analyzed. Results Compared with that of the control group, the incidence of multiple organ dysfunction syndrome (MODS) and severe acute pancreatitis (SAP) of the observation group was lower (P<0.05), and the reduction before and after treatment of APACHEⅡ score, BISAP score and Ranson score in the observation group was more than those in the control group (P<0.05). Compared with that of the control group, the recovery time of flatus and bowel movement and duration of fasting food and water of the observation group was shorter (P<0.05). The reduction before and after treatment of the scores of TCM syndromes (abdominal pain, abdominal distention, nausea and vomiting, dry mouth and bitter taste) and numerical value of blood amylase (AMY), alanine aminotransferase (ALT), alanine aminotransferase (AST) and C-reactive protein (CRP) in the observation group were more than those in the control group (P<0.05). Compared with that of the control group (83.33%), the total effective rate of the scores of TCM syndromes (95.59%) of the observation group was higher (P<0.05).Conclusion Yidantong recipe retained enema combined with external application of Jinhuang powder in the treatment of NSAP is effective by combining with routine Western medicine.

Citation： DENG Gao, WU Pengyu, QIN Haizhi, XI Heng, WANG Xinxin, CHEN Min. Yidantong recipe combined with Jinhuang powder in treating non-severe acute pancreatitis from the perspective of “blood stasis”: a retrospective cohort study. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2024, 31(2): 182-188. doi: 10.7507/1007-9424.202401049 Copy

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