Guidelines for high-flow nasal cannula oxygen therapy in neonates (2023)_Chinese Journal of Evidence-Based Medicine

Authors：

HUANG Yi ¹ , ZHAO Jing ^1,2 , HUA Xintian ^1,2 , LUO Keren ^1,2 , SHI Yuan ³ , LIN Zhenlang ⁴ ,  TANG Jun ^1,2 ,  FENG Zhichun ^5,6,7,8 ,  MU Dezhi ^1,2 , Evidence-Based Medicine Group, Neonatologist Society, Chinese Medical Doctor Association

1. Department of Neonatology, West China Second University Hospital, Sichuan University, Chengdu 610041, P. R. China;
2. Key Laboratory of Birth Defects and Related Diseases of Women and Children, Ministry of Education, Chengdu 610041, P. R. China;
3. Department of Neonatology, Children’s Hospital of Chongqing Medical University, Chongqing 400014, P. R. China;
4. The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, P. R. China;
5. Faculty of Pediatrics, the Chinese PLA General Hospital, Beijing 100007, P. R. China;
6. Research Institute of Pediatric Medicine Department, the 7th Medical Center of PLA General Hospital, Beijing 100007, P. R. China;
7. National Engineering Laboratory for Birth Defects Prevention and Control of Key Technology, Beijing 100007, P. R. China;
8. Beijing Key Laboratory of Pediatric Organ Failure, Beijing 100007, P. R. China;

Corresponding author：

TANG Jun, Email: tj1234753@sina.com; FENG Zhichun, Email: zhjfengzc@126.com; MU Dezhi, Email: mudz@scu.edu.cn

Keywords：

Oxygen inhalation therapy; Nasal cannula; High-flow; Guideline; Infant, newborn

DOI：

10.7507/1672-2531.202309076

Video：

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High-flow nasal cannula (HFNC) oxygen therapy, which is important in noninvasive respiratory support, is increasingly being used in critically ill neonates with respiratory failure because it is comfortable, easy to set up, and has a low incidence of nasal trauma. The advantages, indications, and risks of HFNC have been the focus of research in recent years, resulting in the development of the application. Based on current evidence, we developed guidelines for HFNC in neonates using the grading of recommendations assessment, development and evaluation (GRADE). The guideline was formulated after extensive consultations with neonatologists, respiratory therapists, nurse specialists, and evidence-based medicine experts. We have proposed 24 recommendations for 9 key questions. This guideline aims to be a source of evidence and references of HFNC oxygen therapy in clinical practice, and so that more neonates and their families will benefit from HFNC.

Citation： HUANG Yi, ZHAO Jing, HUA Xintian, LUO Keren, SHI Yuan, LIN Zhenlang, TANG Jun, FENG Zhichun, MU Dezhi, Evidence-Based Medicine Group, Neonatologist Society, Chinese Medical Doctor Association. Guidelines for high-flow nasal cannula oxygen therapy in neonates (2023). Chinese Journal of Evidence-Based Medicine, 2024, 24(4): 385-404. doi: 10.7507/1672-2531.202309076 Copy

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Chinese Journal of Evidence-Based Medicine

Guidelines for high-flow nasal cannula oxygen therapy in neonates (2023)

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