• Department of Surgery, Shanghai Sixth People’s Hospital, Shanghai 200033;
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Objective  To observe the effect of parenteral nutrition (PN) on the protein storage and immunofunction in patients with liver cirrhosis.
Methods  PN regimes consisted of nonprotein calories (NPC) 20-25 kcal/(kg·d) and nitrogen 0.15-0.20 g/(kg·d), the energy ratio of the glucose and fat emulsion was 2∶1. The PN solution was infused by total nutrition admixture (TNA), 12-16 hours per day for 7 days in 21 liver cirrhosis patients. Perior to the surgery and at 1st, 4th, 7th postoperative day, serum pre-Alb, transferrin (TSF), immunofunction (IgG, IgA, IgM, IgE, CH50, C3, C4, CD3, CD4, CD8, NKC), and nitrogen balance were tested.
Results  Serum pre-Alb, TSF, nitrogen balance and IgG, IgE, CH50, CD3, CD4, NKC were significantly decreased (P<0.05), but the foregoing indices were higher than those of postoperative 1, 4d as compared with postoperative 7d.
Conclusion  These results bly indicated that postoperative nutritional support is safe and useful, and improve the patient’s nutritional status and immunofunction.

Citation: QIN Huanlong,WU Zhaohan.. NUTRITIONAL SUPPORT IMPROVED THE NUTRITIONAL STATUS AND IMMUNOFUNCTION OF THE PATIENTS WITH LIVER DISEASE. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2000, 7(5): 308-310. doi: Copy