Effects of vitrectomy combined with intraocular silicon oil or C<sub>3</sub>F<sub>8</sub> tamponade on vitreous hemorrhage due to proliferative diabetic retinopathy_Chinese Journal of Ocular Fundus Diseases

Authors：

WangYing , JiangFeng , HanJindong ,  颜华

Department of Ophthalmology, General Hospital of Tianjin Medical University, Tianjin 300052, China;

Corresponding author：

颜华, Email: phuayan2000@163.com

Keywords：

Diabetic retinopathy/complications; Vitreous hemorrhage/surgery; Vitrectomy; Silicone oils/therapeutic use; Noble gases/therapeutic use

DOI：

10.3760/cma.j.issn.1005-1015.2014.02.008

Video：

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Objective To observe the effect and complications of vitrectomy combined with intraocular silicon oil or C₃F₈ filling for proliferative diabetic retinopathy (PDR). Methods Eighty-six consecutive patients (101 eyes) with PDR-related vitreous hemorrhage who underwent primary standard three-port vitrectomy and intraocular tamponade of silicone oil or C₃F₈ were included in this retrospective study. They were divided into silicone oil group and C₃F₈ groups. There was no statistically significant difference between these two groups of patients for gender, age, duration of diabetes, fasting glucose, history of hypertension, diabetic kidney disease history, history of cardiac and vascular diseases, body mass index and smoking history. There was statistically significant difference between these two groups of patients for visual acuity (Z=-2.604, P=0.009). There was no statistically significant difference between these two groups of patients for intraocular pressure before surgery (Z=0.064, P=0.949). The mean follow-up was (20.3±16.4) months with a range from 1 to 47 months. The patients were followed up for visual acuity, intraocular pressure, neovascular glaucoma (NVG), the incidence of retinal detachment, recurrent vitreous hemorrhage, and repeated operation for complications. Results Visual acuity (t=-3.932, -8.326; P=0.000, 0.000) and intraocular pressure (t=-3.159, -2.703; P=0.006, 0.009) were changed significantly after surgery for both groups. Between these two groups after surgery, there were significant differences of visual acuity (Z=-1.879, P=0.040), intraocular pressure (Z=-3.593, P=0.000), and complications (revision operation, retinal detachment, recurrent vitreous hemorrhage and NVG) (t=-2.777, -2.102, -2.308, -2.013; P < 0.05). Conclusion Intraocular silicone oil tamponade can reduce the postoperative complications of PDR, especially for severe retinal neovascularization, exudation associated with retinal edema.

Citation： WangYing, JiangFeng, HanJindong. Effects of vitrectomy combined with intraocular silicon oil or C₃F₈ tamponade on vitreous hemorrhage due to proliferative diabetic retinopathy. Chinese Journal of Ocular Fundus Diseases, 2014, 30(2): 148-151. doi: 10.3760/cma.j.issn.1005-1015.2014.02.008 Copy

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1. 王冰, 陈平, 翁景宁.增殖性糖尿病视网膜病变玻璃体手术并发症分析[J].国际眼科杂志, 2008, 8:1259-1261.
2. Douglas MJ, Scott IU, Flynn HW Jr. Pars plana lensectomy, pars plana vitrectomy, and silicone oil tamponade as initial management of cataract and combined traction/rhegmatogenous retinal detachment involving the macula associated with severe proliferative diabetic retinopathy[J]. Ophthalmic Surg Lasers Imaging, 2003, 34:270-278.
3. Wilkinson CP, Ferris FL 3rd, Klein RE, et al. Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales[J]. Ophthalmology, 2003, 110:1677-1682.
4. Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1:diagnosis and classification of diabetes mellitus provisional report of a WHO consultation[J]. Diabet Med, 1998, 15:539-553.
5. Mati Ac'G S, Sui SP, Biuk D, et al. Influence of silicone oil tamponade after vitrectomy on intraocular pressure[J]. Coll Antropol, 2013, 37 Suppl 1:S227-235.
6. Kharrat W, Turki K, Ben Amor H, et al. Use of silicone oil in vitreal hemorrhage complicating proliferated diabetic retinopathy[J]. J Fr Ophtalmol, 2009, 32:98-103.
7. Teke MY, Elgin U, Sen E, et al. Intravitreal silicone oil induced changes in corneal biomechanics[J/OL].. Int Ophthalmol, 2013[2013-10-20]. http://link.springer.com/article/10.1007%2Fs10792-013-9830-7.[published online ahead of print, July 16, 2013].

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Effects of vitrectomy combined with intraocular silicon oil or C₃F₈ tamponade on vitreous hemorrhage due to proliferative diabetic retinopathy

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Effects of vitrectomy combined with intraocular silicon oil or C₃F₈ tamponade on vitreous hemorrhage due to proliferative diabetic retinopathy