单纯23G玻璃体切割手术与玻璃体腔注射抗血管内皮生长因子单克隆抗体ranibizumab联合23G玻璃体切割手术治疗增生型糖尿病视网膜病变对比观察_Chinese Journal of Ocular Fundus Diseases

Authors：

冯萧萧 ,  肖丽波 , 胡竹林 , 李云琴 , 吴敏

650021 昆明, 云南省第二人民医院眼科;

Corresponding author：

肖丽波, Email: xiaolibo878@gmail.com

Keywords：

糖尿病视网膜病变/药物疗法; 糖尿病视网膜病变/外科学; 抗体, 单克隆/治疗应用; 玻璃体切除术

DOI：

10.3760/cma.j.issn.1005-1015.2014.02.017

Video：

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Citation： 冯萧萧, 肖丽波, 胡竹林, 李云琴, 吴敏. 单纯23G玻璃体切割手术与玻璃体腔注射抗血管内皮生长因子单克隆抗体ranibizumab联合23G玻璃体切割手术治疗增生型糖尿病视网膜病变对比观察. Chinese Journal of Ocular Fundus Diseases, 2014, 30(2): 193-194. doi: 10.3760/cma.j.issn.1005-1015.2014.02.017 Copy

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4.	Ribeiro JA, Messias A, de Almeida FP, et al.The effect of intravitreal ranibizumab on intraoperative bleeding during pars plana vitrectomy for diabetic traction retinal detachment[J]. Br J Ophthalmol, 2011, 95:1337-1339.
5.	Presta LG, Chen H, O'Connor SJ, et al.Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders[J].Cancer Res, 1997, 57:4593-4599.
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8.	Von Hann T, Kinge B, Fossen K. Retinal artery occlusion following intravitreal anti-VEGF therapy[J]. Acta Ophthalmol, 2010, 88:263-266.
9.	Fung AE, Rosenfeld PJ, Reichel E.The international intravitreal bevacizumab safety survey:using the internet to assess drug safety worldwide[J].Br J Ophthalmol, 2006, 90:1344-1349.
10.	Angulo Bocco MC, Glacet-Bernard A, Zourdani A, et al. Intravitreous injection:retrospecitive study on 2028 injections and their side effects[J]. J Fr Ophtalmol, 2008, 31:693-698.

1. 傅祖植.糖尿病[M]//叶任高.内科学.5版.北京:人民卫生出版社, 2000:809-810.
2. Castellarin A, Grigorian R, Bhagat N, et al. Vitrectomy with silicone oil infusion in severe diabetic retinopathy[J]. Br J Ophthalmol, 2003, 87:318-321.
3. 何守志.白内障[M]//李凤鸣.中华眼科学.2版.北京:人民卫生出版社, 2006:1455-1457.
4. Ribeiro JA, Messias A, de Almeida FP, et al.The effect of intravitreal ranibizumab on intraoperative bleeding during pars plana vitrectomy for diabetic traction retinal detachment[J]. Br J Ophthalmol, 2011, 95:1337-1339.
5. Presta LG, Chen H, O'Connor SJ, et al.Humanization of an anti-vascular endothelial growth factor monoclonal antibody for the therapy of solid tumors and other disorders[J].Cancer Res, 1997, 57:4593-4599.
6. Chen Y, Wiesmann C, Fuh G, et al. Selection and analysis of an optimized anti-VEGF antibody:crystal structure of an affinity-matured Fab in complex with antigen[J].J Mol Biol, 1999, 293:865-881.
7. Lowe J, Araujo J, Palma M, et al.RhuFab V2 inhibits VEGF-isoforms-stimulated HUVEC proliferation[J]. Invest Ophthalmol Vis Sci, 2003, 44:1828.
8. Von Hann T, Kinge B, Fossen K. Retinal artery occlusion following intravitreal anti-VEGF therapy[J]. Acta Ophthalmol, 2010, 88:263-266.
9. Fung AE, Rosenfeld PJ, Reichel E.The international intravitreal bevacizumab safety survey:using the internet to assess drug safety worldwide[J].Br J Ophthalmol, 2006, 90:1344-1349.
10. Angulo Bocco MC, Glacet-Bernard A, Zourdani A, et al. Intravitreous injection:retrospecitive study on 2028 injections and their side effects[J]. J Fr Ophtalmol, 2008, 31:693-698.

Chinese Journal of Ocular Fundus Diseases

单纯23G玻璃体切割手术与玻璃体腔注射抗血管内皮生长因子单克隆抗体ranibizumab联合23G玻璃体切割手术治疗增生型糖尿病视网膜病变对比观察

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