Comparison of confocal scanning laser ophthalmoscope and color fundus camera to assess retinal and choroidal disease using_Chinese Journal of Ocular Fundus Diseases

Authors：

HuoYanjiao , YangLihong , CuiRui ,  WeiWenbin

Beijing Ophthalmology & Visual Science Key Laboratory, Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China;

Corresponding author：

WeiWenbin, Email: weiwenbintr@163.com

Keywords：

Retinal diseases/diagnosis; Choroid diseases/diagnosis; Tomography, optical coherence

DOI：

10.3760/cma.j.issn.1005-1015.2016.03.010

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To cpmpare the assessment of retinal and choroidal disease using confocal scanning laser ophthalmoscope (cSLO) imaging and color fundus camera. Methods Sixty-seven patients (90 eyes) with fundus diseases were included in this study. There were 35 males (51 eyes) and 32 female (39 eyes), mean age was 51.32 years. All subjects underwent fundus imaging using cSLO technology and traditional color fundus camera, positive numbers of every retinal pathological change were calculated and compared. Spectral domain-optical coherence tomography (SD-OCT) was also done to compare the accordance rate between two modes of fundus imaging (cSLO technology and traditional color fundus camera) and SD-OCT in choroidal changes. Results The positive numbers of retinal microaneurysm (χ²=4.157, P < 0.05) and epiretinal membrane (χ²=5.428, P < 0.05) using cSLO fundus imaging were significantly higher than traditional color fundus camera, while the positive numbers of cotton wool spots (χ²=0.523), retinal hemorrhage (χ²=0.117), hard exudates (χ²=0.325) and macular hole (χ²=0.070) were no significant different (P > 0.05). The SD-OCT accordance rate of choroidal pathological changes using cSLO technology was higher than traditional color fundus camera (χ²=9.143, P=0.007). Conclusion In retinal and choroidal diseases, the imaging quality of cSLO fundus imaging technology is better than the traditional color fundus camera technology.

Citation： HuoYanjiao, YangLihong, CuiRui, WeiWenbin. Comparison of confocal scanning laser ophthalmoscope and color fundus camera to assess retinal and choroidal disease using. Chinese Journal of Ocular Fundus Diseases, 2016, 32(3): 270-274. doi: 10.3760/cma.j.issn.1005-1015.2016.03.010 Copy

1.	De Bats F, Vannier Nitenberg C, Fantino B, et al.Age-related macular degeneration screening using a nonmydriatic digital color fundus camera and telemedicine[J]. Ophthalmologica, 2014, 231(3):172-176.DOI:10.1159/000356695.
2.	Litvin TV, Ozawa GY, Bresnick GH, et al.Utility of hard exudates for the screening of macular edema[J].Optom Vis Sci, 2014, 91(4):370-375.DOI:10.1097/OPX.0000000000000205.
3.	Romero-Aroca P, Sagarra-Alamo R, Basora-Gallisa J, et al.Prospective comparison of two methods of screening for diabetic retinopathy by nonmydriatic fundus camera[J].Clin Ophthalmol, 2010, 4:1481-1488. DOI:10.2147/OPTH.S14521.
4.	Sharp PF, Manivannan A.The scanning laser ophthalmoscope[J].Phys Med Biol, 1997, 42(5):951-966.
5.	Sergott RC.Retinal segmentation using multicolor laser imaging[J].J Neuroophthalmol, 2014, 34 Suppl:S24-28. DOI:10.1097/WNO.0000000000000164.
6.	Etten PG, Brouwere DD, Westers P, et al. Zero dilation ophthalmoscopy[J].J Ophthalmic Photogr, 2014, 36(2):55-62.
7.	Reznicek L, Dabov S, Kayat B, et al. Scanning laser'en face' retinal imaging of epiretinal membranes[J]. Saui J Ophthalmol, 2014, 28(2):134-138.DOI:10.1016/j.sjopt.2014.03.009.
8.	Katome T, Mitamura Y, Nagasawa T, et al. Quantitative analysis of cystoid macular edema using scanning laser ophthalmoscope in modified dark-field imaging[J]. Retina, 2012, 32(9):1892-1899.DOI:10.1097/IAE.0b013e3182497141.
9.	Tanaka Y, Shimada N, Ohno-Matsui K, et al. Retromode retinal imaging of macular retinoschisis in highly myopic eyes[J]. Am J Ophthalmol, 2010, 149(4):635-640. DOI:10.1016/j.ajo.2009.10.024.
10.	Acton JH, Cubbidge RP, King H, et al. Drusen detection in retro-mode imaging by a scanning laser ophthalmoscope[J].Acta Ophthalmol, 2011, 89(5):404-411. DOI:10.111/j.1755-3768.2011.02123.x.
11.	Schmitz-Valckenberg S, Steinberg JS, Fleckenstein M, et al.Combined confocal scanning laser ophthalmoscopy and spectral-domain optical coherence tomography imaging of reticular drusen associated with age-related macular degeneration[J]. Ophthalmology, 2010, 117(6):1169-1176.DOI:10.1016/j.Ophtha.2009.10.044.
12.	Shin YU, Lee BR. Retro-mode imaging for retinal pigment epithelium alterations in central serous chorioretinopathy[J].Am J Ophthalmol, 2012, 154(1):155-163. DOI:10.1016/j.ajo.2012.01.023.
13.	Zeng R, Zhang X, Su Y, et al. The noninvasive retro-mode imaging modality of confocal scanning laser ophthalmoscopy in polypoidal choroidal vasculopathy:a preliminary application. PLoS One, 2013, 8(9):75711. http://europepmc.org/articles/PMC3776759. DOI:10.1371/journal.pone.0075711.eClollection2013.
14.	魏文斌, 陈积中.眼底病鉴别诊断学[M].北京:人民卫生出版社, 2012:159-467.Wei WB, Chen JZ.Differential diagnosis of ophthalmology[M].Beijing:People's Medical Publishing House, 2012:159-467.
15.	Keane PA, Sadda SR.Retinal imaging in the twenty-first century:state of the art and future directions[J].Ophthalmology, 2014, 121(12):2489-2500. DOI:10.1016/j.ophtha.2014.07.054.
16.	霍妍佼, 魏文斌.眼底成像技术新进展——共聚焦激光扫描检眼镜[J].国际眼科纵览, 2015, 39(4):224-228.DOI:10.3760/cma.j.issn.1673-5803.2015.04.002.Huo YJ, Wei WB.Progress in fundus imaging:confocal scanning laser opthalmoscope[J]. Int Rev Ophthalmol, 2015, 39(4):224-228.DOI:10.3760/cma.j.issn.1673-5803.2015.04.002.
17.	Kirkpatrick JN, Manivannan A, Gupta AK, et al.Fundus imaging in patients with cataract:role for a variable wavelength scanning laser ophthalmoscope[J].Br J Ophthalmol, 1995, 79(10):892-899.
18.	Park SP, Siringo FS, Pensec N, et al. Comparison of fundus autofluorescence between fundus camera and confocal scanning laser ophthalmoscope-based systems[J]. Ophthalmic Surg Lasers Imaging Retina, 2013, 44(6):536-543. DOI:10.3928/23258160-20131105-04.
19.	Jia Y, Tan O, Tokayer J, et al. Split-spectrum amplitude-decorrelation angiography with optical coherence tomography[J].Opt Express, 2012, 20(4):4710-4725.DOI:10.1364/OE.20.004710.

1. De Bats F, Vannier Nitenberg C, Fantino B, et al.Age-related macular degeneration screening using a nonmydriatic digital color fundus camera and telemedicine[J]. Ophthalmologica, 2014, 231(3):172-176.DOI:10.1159/000356695.
2. Litvin TV, Ozawa GY, Bresnick GH, et al.Utility of hard exudates for the screening of macular edema[J].Optom Vis Sci, 2014, 91(4):370-375.DOI:10.1097/OPX.0000000000000205.
3. Romero-Aroca P, Sagarra-Alamo R, Basora-Gallisa J, et al.Prospective comparison of two methods of screening for diabetic retinopathy by nonmydriatic fundus camera[J].Clin Ophthalmol, 2010, 4:1481-1488. DOI:10.2147/OPTH.S14521.
4. Sharp PF, Manivannan A.The scanning laser ophthalmoscope[J].Phys Med Biol, 1997, 42(5):951-966.
5. Sergott RC.Retinal segmentation using multicolor laser imaging[J].J Neuroophthalmol, 2014, 34 Suppl:S24-28. DOI:10.1097/WNO.0000000000000164.
6. Etten PG, Brouwere DD, Westers P, et al. Zero dilation ophthalmoscopy[J].J Ophthalmic Photogr, 2014, 36(2):55-62.
7. Reznicek L, Dabov S, Kayat B, et al. Scanning laser'en face' retinal imaging of epiretinal membranes[J]. Saui J Ophthalmol, 2014, 28(2):134-138.DOI:10.1016/j.sjopt.2014.03.009.
8. Katome T, Mitamura Y, Nagasawa T, et al. Quantitative analysis of cystoid macular edema using scanning laser ophthalmoscope in modified dark-field imaging[J]. Retina, 2012, 32(9):1892-1899.DOI:10.1097/IAE.0b013e3182497141.
9. Tanaka Y, Shimada N, Ohno-Matsui K, et al. Retromode retinal imaging of macular retinoschisis in highly myopic eyes[J]. Am J Ophthalmol, 2010, 149(4):635-640. DOI:10.1016/j.ajo.2009.10.024.
10. Acton JH, Cubbidge RP, King H, et al. Drusen detection in retro-mode imaging by a scanning laser ophthalmoscope[J].Acta Ophthalmol, 2011, 89(5):404-411. DOI:10.111/j.1755-3768.2011.02123.x.
11. Schmitz-Valckenberg S, Steinberg JS, Fleckenstein M, et al.Combined confocal scanning laser ophthalmoscopy and spectral-domain optical coherence tomography imaging of reticular drusen associated with age-related macular degeneration[J]. Ophthalmology, 2010, 117(6):1169-1176.DOI:10.1016/j.Ophtha.2009.10.044.
12. Shin YU, Lee BR. Retro-mode imaging for retinal pigment epithelium alterations in central serous chorioretinopathy[J].Am J Ophthalmol, 2012, 154(1):155-163. DOI:10.1016/j.ajo.2012.01.023.
13. Zeng R, Zhang X, Su Y, et al. The noninvasive retro-mode imaging modality of confocal scanning laser ophthalmoscopy in polypoidal choroidal vasculopathy:a preliminary application. PLoS One, 2013, 8(9):75711. http://europepmc.org/articles/PMC3776759. DOI:10.1371/journal.pone.0075711.eClollection2013.
14. 魏文斌, 陈积中.眼底病鉴别诊断学[M].北京:人民卫生出版社, 2012:159-467.Wei WB, Chen JZ.Differential diagnosis of ophthalmology[M].Beijing:People's Medical Publishing House, 2012:159-467.
15. Keane PA, Sadda SR.Retinal imaging in the twenty-first century:state of the art and future directions[J].Ophthalmology, 2014, 121(12):2489-2500. DOI:10.1016/j.ophtha.2014.07.054.
16. 霍妍佼, 魏文斌.眼底成像技术新进展——共聚焦激光扫描检眼镜[J].国际眼科纵览, 2015, 39(4):224-228.DOI:10.3760/cma.j.issn.1673-5803.2015.04.002.Huo YJ, Wei WB.Progress in fundus imaging:confocal scanning laser opthalmoscope[J]. Int Rev Ophthalmol, 2015, 39(4):224-228.DOI:10.3760/cma.j.issn.1673-5803.2015.04.002.
17. Kirkpatrick JN, Manivannan A, Gupta AK, et al.Fundus imaging in patients with cataract:role for a variable wavelength scanning laser ophthalmoscope[J].Br J Ophthalmol, 1995, 79(10):892-899.
18. Park SP, Siringo FS, Pensec N, et al. Comparison of fundus autofluorescence between fundus camera and confocal scanning laser ophthalmoscope-based systems[J]. Ophthalmic Surg Lasers Imaging Retina, 2013, 44(6):536-543. DOI:10.3928/23258160-20131105-04.
19. Jia Y, Tan O, Tokayer J, et al. Split-spectrum amplitude-decorrelation angiography with optical coherence tomography[J].Opt Express, 2012, 20(4):4710-4725.DOI:10.1364/OE.20.004710.

Chinese Journal of Ocular Fundus Diseases

Comparison of confocal scanning laser ophthalmoscope and color fundus camera to assess retinal and choroidal disease using

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content