Clinical applications of optical coherence tomography angiography_Chinese Journal of Ocular Fundus Diseases

Authors：

 LiXiaoxin , ShiXuan

Department of Ophthalmology, Peking University People’s Hospital, Key Laboratory of Vision Loss and Restoration (Peking University), Ministry of Education, Beijing 100044, China;

Corresponding author：

LiXiaoxin, Email: dr_lixiaoxin@163.com

Keywords：

Retinal diseases/diagnosis; Choroid diseases/diagnosis; Tomography, optical coherence; Editorial

DOI：

10.3760/cma.j.issn.1005-1015.2017.01.002

Video：

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Abstract Full text Figures/Tables Video References Cited by

Optic coherence tomography (OCT) is one of the most rapid developing technologies in ophthalmology. OCT angiography (OCTA) has been made possible by the development of even faster scanning and sampling techniques, which is the next milestone after stratus OCT and spectral domain OCT. Without the need of injection of the contrast agent, OCTA is capable of providing a three-dimensional reconstruction of the perfused microvasculature within the retina and choroid by detecting the motion of scattering particles such as erythrocytes within sequential OCT cross-sectional scans performed repeatedly at the same location of the eye with different analysis algorithms. Comparing to fundus fluorescein angiography and indocyanine green angiography, with improved OCT technology and understanding, OCTA has showed certain advantages to diagnose retinal and choroidal diseases, especially macular vascular diseases. It is important to establish the contributions that OCTA can make to diagnosing, managing and understanding of ocular fundus diseases.

Citation： LiXiaoxin, ShiXuan. Clinical applications of optical coherence tomography angiography. Chinese Journal of Ocular Fundus Diseases, 2017, 33(1): 3-6. doi: 10.3760/cma.j.issn.1005-1015.2017.01.002 Copy

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20.	Roisman L, Zhang Q, Wang RK, et al. Optical coherence tomography angiography of asymptomatic neovascularization in intermediate age-related macular degeneration[J]. Ophthalmology, 2016, 123(6): 1309-1319. DOI: 10.1016/j.ophtha.2016.01.044.

1. Puliafit CA. CT angiography: the next era of OCT technology emerges[J]. Ophthalmic Surg Lasers Imaging Retina, 2014, 45(5): 360. DOI: 10.3928/23258160-20140925-01.
2. Jia Y, Tan O, Tokayer J, et al. Split-spectrum amplitude-decorrelation angiography with optical coherence tomography[J]. Opt Express, 2012, 20(4): 4710-4725. DOI: 10.1364/OE.20.004710.
3. An L, Shen TT, Wang RK.Using ultrahigh sensitive optical microangiography to achieve comprehensive depth resolved microvasculature mapping for human retina[J/OL]. J Biomed Opt, 2011, 16(10): 106013[2011-10-24]. 10.1117/1.3642638">https://biomedicaloptics. spiedigitallibrary.org/article.aspx?doi=10.1117/1.3642638. DOI: 10.1117/1.3642638.
4. Spaide RF, Klancnik JM Jr, Cooney MJ, et al. Volume-rendering optical coherence tomography angiography of macular telangiectasia type 2[J]. Ophthalmology, 2015, 122(11): 2261-2269. DOI: 10.1016/j.ophtha.2015.07.025.
5. Zhang Q, Wang RK, Chen CL, et al. Swept source optical coherence tomography angiography of neovascular macular telangiectasia type 2[J]. Retina, 2015, 35(11): 2285-2299. DOI: 10.1097/IAE. 0000000000000840.
6. Spaide RF, Klancnik JM Jr, Cooney MJ. Retinal vascular layers in macular telangiectasia type 2 imaged by optical coherence tomographic angiography[J]. JAMA Ophthalmol, 2015, 133(1): 66-73. DOI: 10.1001/jamaophthalmol.2014.3950.
7. Garcia JM, Lima TT, Louzada RN, et al. Diabetic macular ischemia diagnosis: comparison between optical coherence tomography angiography and fluorescein angiography[J/OL]. J Ophthalmol, 2016, 2016: 3989310[2016-11-07]. https://dx.doi.org/10.1155/ 2016/3989310.
8. Soares M, Neves C, Marques IP, et al. Comparison of diabetic retinopathy classification using fluorescein angiography and optical coherence tomography angiography[J]. Br J Ophthalmol, 2017, 101(1): 62-68. DOI: 10.1136/bjophthalmol-2016-309424.
9. Shahlaee A, Samara WA, Hsu J, et al. In vivo assessment of macular vascular density in healthy human eyes using optical coherence tomography angiography[J]. Am J Ophthalmol, 2016, 165: 39-46. DOI: 10.1016/j.ajo.2016.02.018.
10. Adhi M, Filho MA, Louzada RN, et al. Retinal capillary network and foveal avascular zone in eyes with vein occlusion and fellow eyes analyzed with optical coherence tomography angiography[J]. Invest Ophthalmol Vis Sci, 2016, 57(9): 486-494. DOI: 10.1167/ iovs.15-18907.
11. Suzuki N, Hirano Y, Yoshida M, et al. Microvascular abnormalities on optical coherence tomography angiography in macular edema associated with branch retinal vein occlusion[J]. Am J Ophthalmol, 2016, 161: 126-132. DOI: 10.1016/j.ajo.2015.09.038.
12. Coscas GJ, Lupidi M, Coscas F, et al. Optical coherence tomography angiography versus traditional imaging in assessing the activity of exudative age-related macular degeneration: a new diagnostic challenge[J]. Retina, 2015, 35(11): 2219-2228. DOI: 10.1097/ IAE.0000000000000766.
13. Muakkassa NW, Chin AT, de Carlo T, et al. Chracterizing the effect of anti-vascular endothelial growth factor therapy on treatment-naïve choroidal neovascularization using optical coherence angiography[J]. Retina, 2015, 35(11): 2252-2259. DOI: 10.1097/ IAE.0000000000000836.
14. Inoue M, Jung JJ, Balaratnasingam C, et al. A comparison between optical coherence tomography angiography and fluorescein angiography for the imaging of type 1 neovascularization[J]. Invest Ophthalmol Vis Sci, 2016, 57(9): 314-323. DOI: 10.1167/iovs.15-18900.
15. Cole ED, Ferrara D, Novais EA, et al. Clinical trial endpoints for optical coherence tomography angiography in neovascular age-related macular degeneration[J]. Retina, 2016, 36 Suppl 1: S83-92. DOI: 10.1097/IAE.0000000000001338.
16. Kim JY, Kwon OW, Oh HS, et al. Optical coherence tomography angiography in patients with polypoidal choroidal vasculopathy[J]. Graefe’s Arch Clin Exp Ophthalmol, 2016, 254(8): 1505-1510. DOI: 10.1007/s00417-015-3228-3.
17. Tomiyasu T, Nozaki M, Yoshida M, et al. Characteristics of polypoidal choroidal vasculopathy evaluated by optical coherence tomography angiography[J]. Invest Ophthalmol Vis Sci, 2016, 57(9): 324-330. DOI: 10.1167/iovs.15-18898.
18. Takayama K, Ito Y, Kaneko H, et al. Comparison of indocyanine green angiography and optical coherence tomographic angiography in polypoidal choroidal vasculopathy[J/OL]. Eye (Lond), 2016, 2016: E1[2016-0-11-04]. http://dx.doi.org/10.1038/eye.2016.232. DOI: 10.1038/eye.2016.232. [published online ahead of print].
19. Costanzo E, Cohen SY, Miere A, et al. Optical coherence tomography angiography in central serous chorioretinopathy[J/OL]. J Ophthalmol, 2015, 2015: 134783[2015-11-08]. 10.1155/2015/134783">https://dx. doi.org/10.1155/2015/134783. DOI: 10.1155/2015/ 134783.
20. Roisman L, Zhang Q, Wang RK, et al. Optical coherence tomography angiography of asymptomatic neovascularization in intermediate age-related macular degeneration[J]. Ophthalmology, 2016, 123(6): 1309-1319. DOI: 10.1016/j.ophtha.2016.01.044.

Chinese Journal of Ocular Fundus Diseases

Clinical applications of optical coherence tomography angiography

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