Spectral-domain optical coherence tomography characteristics of acute central serous chorioretinopathy_Chinese Journal of Ocular Fundus Diseases

Authors：

 Wang Zhen , Tan Xiaojun , Chen Cui , Wang Xuefeng , Li Mengyun

Affiliated Yidu Central Hospital of Weifang Medical College, Weifang 262500, China;

Corresponding author：

Wang Zhen, Email: wbaiqiuen@qq.com

Keywords：

Central serous chorioretinopathy; Tomography, optical coherence; Fluorescein fundus angiography

DOI：

10.3760/cma.j.issn.1005-1015.2017.06.005

Video：

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Objective To observe the characteristics of spectral-domain optical coherence tomography (SD-OCT) for leakage point in acute central serous chorioretinopathy (CSC). Methods A total of 21 acute CSC patients (21 eyes) were enrolled in this retrospective study, including 17 men (17 eyes) and 4 women (5 eyes). The mean age was (47.3±8.8) years (range 35 - 66 years). The mean duration was (1.6±0.8) months (range 0.5 - 3.0 months). All patients were underwent mydriatic fundus photography, SD-OCT examination and fluorescein fundus angiography (FFA). SD-OCT and FFA images were carefully compared to observe the SD-OCT examination characteristics of fluorescence leakage point. Results 21/21 eyes had one fluorescein leakage point. In addition to serous retinal detachment, leakage point in the SD-OCT examination showed retinal pigment epithelium (RPE) protrusion in 10 eyes (47.6％), RPE detachment in 7 eyes (33.3％), highly reﬂective areas suggesting ﬁbrinous exudate in the subretinal space in 3 eyes (14.3％), and RPE defect in 1 eye (4.8％). Conclusion The SD-OCT characteristics of acute CSC include RPE protrusion, RPE detachment, highly reﬂective areas suggesting ﬁbrinous exudate in the subretinal space and RPE defect.

Citation： Wang Zhen, Tan Xiaojun, Chen Cui, Wang Xuefeng, Li Mengyun. Spectral-domain optical coherence tomography characteristics of acute central serous chorioretinopathy. Chinese Journal of Ocular Fundus Diseases, 2017, 33(6): 577-579. doi: 10.3760/cma.j.issn.1005-1015.2017.06.005 Copy

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10.	潘中婷,赵明威,董冲亚,等.低剂量维替泊芬光动力疗法治疗急性中心性浆液性脉络膜视网膜病变的回顾性研究[J].中华眼底病杂志,2014,30 (4): 369-373.Pan ZT,Zhao MW,Dong CY,et al.Retrospective study of low-dose verteporfin photodynamic therapy for acute central serous chorioretinopathy[J]. Chin J Ocul Fundus Dis, 2014,30 (4): 369-373.
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1. Wang M, Munch IC, Hasler PW, et al. Central serous chorioretinopathy [J]. Acta Ophthalmol, 2008, 86(2): 126-145. DOI:10.1111/j.1600-0420.2007.00889.x.
2. Daruich A, Matet A, Dirani A, et al. Central serous chorioretinopathy: recent findings and new physiopathology hypothesis[J]. Prog Retin Eye Res, 2015, 48: 82-118. DOI:10.1016/j.preteyeres.2015.05.003.
3. Lim JW, Kang SW, Kim YT, et al. Comparative study of patients with central serous chorioretinopathy undergoing focal laser photocoagulation or photodynamic therapy [J]. Br J Ophthalmol, 2011, 95(4): 514-517. DOI: 10.1136/bjo.2010.182121.
4. Ficker L, Vafidis G, While A, et al. Long-term follow-up of a prospective trial of argon laser photocoagulation in thetreatment of central serous retinopathy[J].Br J Ophthalmol, 1988, 72(11): 829-834.
5. 卢宁, 王光璐, 张风, 等. 多发性后极部色素上皮病变的吲哚青绿和荧光素眼底血管造影[J]. 中华眼底病杂志, 2000, 16(1): 6-8.Lu N, Wang GL, Zhang F, et al. Indocyanine green and fluorescein angiographies of multifocal posterior pigment epitheliopathy[J]. Chin J Ocul Fundus Dis, 2000, 16(1): 6-8.
6. Hangai M, Ojima Y, Gotoh N, et al. Three-dimensional imaging of macular holes with high-speed optical coherence tomography [J]. Ophthalmology, 2007, 114(4): 763-773.DOI:10.1016/j.ophtha.2006.07.055.
7. Wojtkowski M, Bajraszewski T, Gorczyńska I, et al. Ophthalmic imaging by spectral optical coherence tomography [J]. Am J Ophthalmol, 2004, 138(3): 412-419. DOI:10.1016/j.ajo.2004.04.049.
8. Fujimoto H, Gomi F, Wakabayashi T, et al. Morphologic changes in acute central serous chorioretinopathy evaluated by fourier-domain optical coherence tomography [J]. Ophthalmology, 2008, 115(9): 1494-1500. DOI: 10.1016/j.ophtha.2008.01.021.
9. 赵明威. 努力探索发病机制, 进一步提升治疗水平: 中心性浆液性脉络膜视网膜病变研究的现实与挑战[J]. 中华眼底病杂志, 2011, 27(4): 305-308. DOI:10.3760/cma.j.issn.1005-1015.2011.04.001.Zhao MW. The pathogenesis and the clinical management: the challenges of treatment of central serous chorioretinopathy faced in reality[J].Chin J Ocul Fundus Dis, 2011, 27(4): 305-308. DOI:10.3760/cma.j.issn.1005-1015.2011.04.001.
10. 潘中婷,赵明威,董冲亚,等.低剂量维替泊芬光动力疗法治疗急性中心性浆液性脉络膜视网膜病变的回顾性研究[J].中华眼底病杂志,2014,30 (4): 369-373.Pan ZT,Zhao MW,Dong CY,et al.Retrospective study of low-dose verteporfin photodynamic therapy for acute central serous chorioretinopathy[J]. Chin J Ocul Fundus Dis, 2014,30 (4): 369-373.
11. Yannuzzi LA, Rohrer KT, Tindel LJ, et al. Fluorescein angiography complication survey[J]. Ophthalmology, 1986, 93(5): 611-617.
12. Yang L, Jonas JB, Wei W. Optical coherence tomography-assisted enhanced depth imaging of central serous chorioretinopathy [J]. Invest Ophthalmol Vis Sci, 2013, 54 (7): 4659-4665.DOI:10.1167/iovs.12-10991.

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