A new insight of the value of laser photocoagulation on retinal vascular diseases_Chinese Journal of Ocular Fundus Diseases

Authors：

Wang Haiyan ,  Wang Yusheng

Department of Ophthalmology, Eye Institute of Chinese PLA, Xijing Hospital, Forth Military Medical University, Xi’an 710032, China;

Corresponding author：

Wang Yusheng, Email: wangys003@126.com

Keywords：

Macular edema/therapy; Diabetic retinopathy/therapy; Retinal vein occlusion/therapy; Laser coagulation; Editorial

DOI：

10.3760/cma.j.issn.1005-1015.2018.05.002

Video：

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Abstract Full text Figures/Tables Video References Cited by

Macular edema is a common cause of visual loss in patients with retinal vascular diseases represented by diabetic retinopathy and retinal vein occlusion. Laser photocoagulation has been the main treatment for this kind of diseases for decades. With the advent of antagonist of vascular endothelial growth factor and dexamethasone implant, diabetic macular edema and macular edema secondary to retinal vein occlusion have been well controlled; the use of laser therapy is decreasing. However, considering possible risks and complications, lack of extended inspection of efficacy and safety of intravitreal pharmacotherapy, laser therapy cannot be replaced by now. Therefore, the efficacy and safety of laser therapy will improve by sober realization of role of photocoagulation and proper selection of treatment indication.

Citation： Wang Haiyan, Wang Yusheng. A new insight of the value of laser photocoagulation on retinal vascular diseases. Chinese Journal of Ocular Fundus Diseases, 2018, 34(5): 424-428. doi: 10.3760/cma.j.issn.1005-1015.2018.05.002 Copy

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1. Hayreh SS. Ocular vascular occlusive disorders: natural history of visual outcome[J]. Prog Retin Eye Res, 2014, 41: 1-25. DOI: 10.1016/j.preteyeres.2014.04.001.
2. Tan GS, Cheung N, Simó R, et al. Diabetic macular oedema[J]. Lancet Diabetes Endocrinol, 2017, 5(2): 143-155. DOI: 10.1016/S2213-8587(16)30052-3.
3. Khayat M, Williams M, Lois N. Ischemic retinal vein occlusion: characterizing the more severe spectrum of retinal vein occlusion[J/OL]. Surv Ophthalmol, 2018, 2018:E1[2018-04-27] . https://linkinghub.elsevier.com/retrieve/pii/S0039-6257(17)30113-3. DOI: 10.1016/j.survophthal.2018.04.005.[published online ahead of print].
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5. Diabetic Retinopathy Study Research Group. Photocoagulation treatment of proliferative diabetic retinopathy: clinical application of Diabetic Retinopathy Study (DRS) findings, DRS report number 8[J]. Ophthalmology, 1981, 88(7): 583-600.
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7. Branch Vein Occlusion Study Group. Argon laser photocoagulation for macular edema in branch vein occlusion[J]. Am J Ophthalmol, 1984, 98(3): 271-282.
8. Early Treatment Diabetic Retinopathy Study Research Group. Photocoagulation for diabetic macular edema. ETDRS report number 1[J]. Arch Ophthalmol, 1985, 103(12): 1796-1806.
9. Nguyen QD, Brown DM, Marcus DM, et al. Ranibizumab for diabetic macular edema: results from 2 phase Ⅲ randomized trials: RISE and RIDE[J]. Ophthalmology, 2012, 119(4): 789-801. DOI: 10.1016/j.ophtha.2011.12.039.
10. Heier JS, Korobelnik JF, Brown DM, et al. Intravitreal aflibercept for diabetic macular edema: 148-week results from the VISTA and VIVID studies[J]. Ophthalmology, 2016, 123(11): 2376-2385. DOI: 10.1016/j.ophtha.2016.07.032.
11. Campochiaro PA, Brown DM, Awh CC, et al. Sustained benefits from ranibizumab for macular edema following central retinal vein occlusion: twelve-month outcomes of a phase Ⅲ study[J]. Ophthalmology, 2011, 118(10): 2041-2049. DOI: 10.1016/j.ophtha.2011.02.038.
12. Pearson PA, Comstock TL, Ip M, et al. Fluocinolone acetonide intravitreal implant for diabetic macular edema: a 3-year multicenter, randomized, controlled clinical trial[J]. Ophthalmology, 2011, 118(8): 1580-1587. DOI: 10.1016/j.ophtha.2011.02.048.
13. Li X, Wang N, Liang X, et al. Safety and efficacy of dexamethasone intravitreal implant for treatment of macular edema secondary to retinal vein occlusion in Chinese patients: randomized, sham-controlled, multicenter study[J]. Graefe’s Arch Clin Exp Ophthalmol, 2018, 256(1): 59-69. DOI: 10.1007/s00417-017-3831-6.
14. Boyer DS, Yoon YH, Belfort R Jr, et al. Three-year, randomized, sham-controlled trial of dexamethasone intravitreal implant in patients with diabetic macular edema[J]. Ophthalmology, 2014, 121(10): 1904-1914. DOI: 10.1016/j.ophtha.2014.04.024.
15. Wong TY, Sun J, Kawasaki R, et al. Guidelines on diabetic eye care: the international council of ophthalmology recommendations for screening, follow-up, referral, and treatment based on resource settings[J/OL]. Ophthalmology, 2018, 2018:E1[2018-05-24] . https://linkinghub.elsevier.com/retrieve/pii/S0161-6420(17)33523-6. DOI: 10.1016/j.ophtha.2018.04.007.[published online ahead of print].
16. Pulido JS, Flaxel CJ, Adelman RA, et al. Retinal vein occlusions preferred practice in pattern (®) guidelines[J]. Ophthalmology, 2016, 123(1): 182-208. DOI: 10.1016/j.ophtha.2015.10.045.
17. Tang J, Kern TS. Inflammation in diabetic retinopathy[J]. Prog Retin Eye Res, 2011, 30(5): 343-358. DOI: 10.1016/j.preteyeres.2011.05.002.
18. Aiello LP, Avery RL, Arrigg PG, et al. Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders[J]. N Engl J Med, 1994, 331(22): 1480-1487.
19. Schmidt-Erfurth U, Garcia-Arumi J, Bandello F, et al. Guidelines for the management of diabetic macular edema by the european society of retina specialists (EURETINA)[J]. Ophthalmologica, 2017, 237(4): 185-222. DOI: 10.1159/000458539.
20. Callanan DG, Gupta S, Boyer DS, et al. Dexamethasone intravitreal implant in combination with laser photocoagulation for the treatment of diffuse diabetic macular edema[J]. Ophthalmology, 2013, 120(9): 1843-1851. DOI: 10.1016/j.ophtha.2013.02.018.
21. Lang GE, Berta A, Eldem BM, et al. Two-year safety and efficacy of ranibizumab 0.5 mg in diabetic macular edema: interim analysis of the RESTORE extension study[J].Ophthalmology, 2013, 120(10): 2004-2012. DOI: 10.1016/j.ophtha.2013.02.019.
22. Elman MJ, Aiello LP, Beck RW, et al. Randomized trial evaluating ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema[J]. Ophthalmology, 2010, 117(6): 1064-1077. DOI: 10.1016/j.ophtha.2010.02.031.
23. Wessel MM, Nair N, Aaker GD, et al. Peripheral retinal ischemia, as evaluated by ultra-widefield fluorescein angiography, is associated with diabetic macular oedema[J]. Br J Ophthalmol, 2012, 96(5): 694-698. DOI: 10.1136/bjophthalmol-2011-300774.
24. Central Vein Occlusion Study Group. Evaluation of grid pattern photocoagulation for macular edema in central vein occlusion. The Central Vein Occlusion Study Group M report[J]. Ophthalmology, 1995, 102(10): 1425-1433.
25. Berger AR, Cruess AF, Altomare F, et al. Optimal treatment of retinal vein occlusion: canadian expert consensus[J]. Ophthalmologica, 2015, 234(1): 6-25. DOI: 10.1159/000381357.
26. Rehak M, Tilgner E, Franke A, et al. Early peripheral laser photocoagulation of nonperfused retina improves vision in patients with central retinal vein occlusion (results of a proof of concept study)[J]. Graefe’s Arch Clin Exp Ophthalmol, 2014, 252(5): 745-752. DOI: 10.1007/s00417-013-2528-8.
27. Campochiaro PA, Heier JS, Feiner L, et al. BRAVO investigators: ranibizumab for macular edema following branch retinal vein occlusion: six-month primary end point results of a phase Ⅲstudy[J]. Ophthalmology, 2010, 117(6): 1102-1112. DOI: 10.1016/j.ophtha.2010.02.021.
28. Azad R, Vivek K, Sharma Y, et al. Ranibizumab as an adjunct to laser for macular edema secondary to branch retinal vein occlusion[J]. Indian J Ophthalmol, 2012, 60(4): 263-266. DOI: 10.4103/0301-4738.98701.
29. Donati S, Barosi P, Bianchi M, et al. Combined intravitreal bevacizumab and grid laser photocoagulation for macular edema secondary to branch retinal vein occlusion[J]. Eur J Ophthalmol, 2012, 22(4): 607-614. DOI: 10.5301/ejo.5000085.
30. Reddy RK, Pieramici DJ, Gune S, et al. Efficacy of ranibizumab in eyes with diabetic macular edema and macular nonperfusion in RIDE and RISE[J/OL]. Ophthalmology, 2018, 2018:E1[2018-05-08]. https://linkinghub.elsevier.com/retrieve/pii/S0161-6420(17)33607-2. DOI: 10.1016/j.ophtha.2018.04.002.[published online ahead of print].
31. Larsen M, Waldstein SM, Boscia F, et al. Individualized ranibizumab regimen driven by stabilization criteria for central retinal vein occlusion: twelve-month results of the CRYSTAL study[J]. Ophthalmology, 2016, 123(5): 1101-1111. DOI: 10.1016/j.ophtha.2016.01.011.
32. Campochiaro PA, Bhisitkul RB, Shapiro H, et al. Vascular endothelial growth factor promotes progressive retinal nonperfusion in patients with retinal vein occlusion[J]. Ophthalmology, 2013, 120(4): 795-802. DOI: 10.1016/j.ophtha.2012.09.032.
33. Campochiaro PA, Wykoff CC, Shapiro H, et al. Neutralization of vascular endothelial growth factor slows progression of retinal nonperfusion in patients with diabetic macular edema[J]. Ophthalmology, 2014, 121(9): 1783-1789. DOI: 10.1016/j.ophtha.2014.03.021.
34. Mir TA, Kherani S, Hafiz G, et al. Changes in retinal nonperfusion associated with suppression of vascular endothelial growth factor in retinal vein occlusion[J]. Ophthalmology, 2016, 123(3): 625-634. DOI: 10.1016/j.ophtha.2015.10.030.
35. Sophie R, Hafiz G, Scott AW, et al. Long-term outcomes in ranibizumab-treated patients with retinal vein occlusion; the role of progression of retinal nonperfusion[J]. Am J Ophthalmol, 2013, 156(4): 693-705. DOI: 10.1016/j.ajo.2013.05.039.
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Chinese Journal of Ocular Fundus Diseases

A new insight of the value of laser photocoagulation on retinal vascular diseases

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