Correct understanding the multimodal imaging to improve the diagnosis and treatment of ocular fundus diseases_Chinese Journal of Ocular Fundus Diseases

Authors：

 Wei Wenbin , Zhou Nan

Beijing Ophthalmology & Visual Science Key Laboratory, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China;

Corresponding author：

Wei Wenbin, Email: tr_weiwenbin@163.com

Keywords：

Retinal diseases/diagnosis; Choroid diseases/diagnosis; Editorial; Multimodal imaging

DOI：

10.3760/cma.j.issn.1005-1015.2019.04.001

Video：

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With the rapid development of ophthalmic imaging methods, there are many ways of examination in the diagnosis and treatment of fundus diseases, such as FFA, ICGA, FAF, OCT and emerging blood vessels by OCT angiography in recent years. Multi-model image can understand the changes of anatomical structure and function of different levels and parts of the fundus from different aspects. A variety of imaging examinations are combined and complemented each other, which makes us have a further understanding of the location and pathological changes of many fundus diseases. But at the same time, the emergence of multi-modal images also brings a series of problems. How to standardize the use of multi-modal imaging platform to better serve the clinic is a problem that ophthalmologists need to understand.

Citation： Wei Wenbin, Zhou Nan. Correct understanding the multimodal imaging to improve the diagnosis and treatment of ocular fundus diseases. Chinese Journal of Ocular Fundus Diseases, 2019, 35(4): 317-321. doi: 10.3760/cma.j.issn.1005-1015.2019.04.001 Copy

1.	Tran K, Pakzad-Vaezi K. Multimodal imaging of diabetic retinopathy[J]. Curr Opin Ophthalmol, 2018, 29(6): 566-575. DOI: 10.1097/ICU.0000000000000524.
2.	Hayreh SS. Recent advances in fluorescein fundus angiography[J]. Br J Ophthalmol, 1974, 58(4): 391-412. DOI: 10.1136/bjo.58.4.391.
3.	Fujimoto J, Swanson E. The development, commercialization, and impact of optical coherence tomography[J]. Invest Ophthalmol Vis Sci, 2016, 57(9): 1-13. DOI: 10.1167/iovs.16-19963.
4.	Nesper PL, Roberts PK, Onishi AC, et al. Quantifying microvascular abnormalities with increasing severity of diabetic retinopathy using optical coherence tomography angiography[J]. Invest Ophthalmol Vis Sci, 2017, 58(6): 307-315. DOI: 10.1167/iovs.17-21787.
5.	霍妍佼, 杨丽红, 崔蕊, 等. 共焦激光扫描检眼镜与彩色眼底照相对视网膜和脉络膜病变的检出比较[J]. 中华眼底病杂志, 2016, 32(3): 270-274. DOI: 10.3760/cma.j.issn.1005-1015.2016.03.010.Huo YJ, Yang LH, Cui R, et al. Comparison of confocal scanning laser ophthalmoscope and color fundus camera to assess retinal and choroidal disease using[J]. Chin J Ocul Fundus Dis, 2016, 32(3): 270-274. DOI: 10.3760/cma.j.issn.1005-1015.2016.03.010.
6.	霍妍佼, 郭彦, 杨丽红, 等. 共聚焦激光扫描检眼镜眼底成像与传统眼底彩色照相对老年人黄斑前膜检出结果比较[J]. 中华眼底病杂志, 2016, 32(6): 615-618. DOI: 10.3760/cma.j.issn.1005-1015.2016.06.012.Huo YJ, Guo Y, Yang LH, et al. Comparison of the screening efficiency of epiretinal membrane using confocal scanning laser ophthalmoscope imaging and color fundus camera in elderly people[J]. Chin J Ocul Fundus Dis, 2016, 32(6): 615-618. DOI: 10.3760/cma.j.issn.1005-1015.2016.06.012.
7.	Paavo M, Zhao J, Kim HJ, et al. Mutations in GPR143/OA1 and ABCA4 inform interpretations of short-wavelength and near-infrared fundus autofluorescence[J]. Invest Ophthalmol Vis Sci, 2018, 59(6): 2459-2469. DOI: 10.1167/iovs.18-24213.
8.	Giani A, Pellegrini M, Carini E, et al. The dark atrophy with indocyanine green angiography in Stargardt disease[J]. Invest Ophthalmol Vis Sci, 2012, 53(7): 3999-4004. DOI: 10.1167/iovs.11-9258.
9.	Klufas MA, Tsui I, Sadda SR, et al. Ultrawidefield autofluoresence in ABC4A Stargardt disease[J]. Retina, 2018, 38(2): 403-415. DOI: 10.1097/IAE.0000000000001567.
10.	McGuigan DB, Heon E, Cideciyan AV, et al. EYS mutations causing autosomal recessive retinitis pigmentosa: changes of retinal structure and function with disease progression[J/OL]. Genes (Basel), 2017, 8(7): 178[2017-07-12]. https://www.mdpi.com/2073-4425/8/7/178. DOI: 10.3390/genes8070178.
11.	陈伟, 杨文利, 魏文斌, 等. 超声弹性成像对眼内肿瘤的鉴别诊断价值[J]. 肿瘤影像学, 2016, 25(4): 303-307. DOI: 10.3969/j.issn.1008-617X.2016.04.003.Chen W, Yang WL, Wei WB, et al. Value of ultrasonic elastosonography in differential diagnosis of intraocular tumors[J]. Oncoradiology, 2016, 25(4): 303-307. DOI: 10.3969/j.issn.1008-617X.2016.04.003.
12.	Balaratnasingam C, Cherepanoff S, Dolz-Marco R, et al. Cuticular drusen: clinical phenotypes and natural history defined using multimodal imaging[J]. Ophthalmology, 2018, 125(1): 100-118. DOI: 10.1016/j.ophtha.2017.08.033.
13.	Pedersen HR, Gilson SJ, Dubra A, et al. Multimodal imaging of small hard retinal drusen in young healthy adults[J]. Br J Ophthalmol, 2018, 102(1): 146-152. DOI: 10.1136/bjophthalmol-2017-310719.
14.	Verdina T, Greenstein VC, Sodi A, et al. Multimodal analysis of the preferred retinal location and the transition zone in patients with Stargardt disease[J]. Graefe's Arch Clin Exp Ophthalmol, 2017, 255(7): 1307-1317. DOI: 10.1007/s00417-017-3637-6.
15.	Pichi F, Veronese C, Lembo A, et al. New appraisals of Kyrieleis plaques: a multimodal imaging study[J]. Br J Ophthalmol, 2017, 101(3): 316-321. DOI: 10.1136/bjophthalmol-2015-308246.
16.	Barbazetto I, Dansingani KK, Yannuzzi LA, et al. Idiopathic acute exudative polymorphous vitelliform maculopathy: clinical spectrum and multimodal imaging characteristics[J]. Ophthalmology, 2018, 125(1): 75-88. DOI: 10.1016/j.ophtha.2017.07.020.
17.	Williams PJ, Robinson J. Multimodal imaging of presumed ocular manifestations in end-stage diffuse large B-cell lymphoma[J]. Retina, 2017, 37(10): 113-115. DOI: 10.1097/IAE.0000000000001821.
18.	Knickelbein JE, Sen HN. Multimodal imaging of the white dot syndromes and related diseases[J/OL]. J Clin Exp Ophthalmol, 2016, 7(3): 570[2016-06-27]. https://www.ncbi.nlm.nih.gov/pubmed/27482471.
19.	Pellegrini M, Acquistapace A, Oldani M, et al. Dark atrophy: an optical coherence tomography angiography study[J]. Ophthalmology, 2016, 123(9): 1879-1886.

1. Tran K, Pakzad-Vaezi K. Multimodal imaging of diabetic retinopathy[J]. Curr Opin Ophthalmol, 2018, 29(6): 566-575. DOI: 10.1097/ICU.0000000000000524.
2. Hayreh SS. Recent advances in fluorescein fundus angiography[J]. Br J Ophthalmol, 1974, 58(4): 391-412. DOI: 10.1136/bjo.58.4.391.
3. Fujimoto J, Swanson E. The development, commercialization, and impact of optical coherence tomography[J]. Invest Ophthalmol Vis Sci, 2016, 57(9): 1-13. DOI: 10.1167/iovs.16-19963.
4. Nesper PL, Roberts PK, Onishi AC, et al. Quantifying microvascular abnormalities with increasing severity of diabetic retinopathy using optical coherence tomography angiography[J]. Invest Ophthalmol Vis Sci, 2017, 58(6): 307-315. DOI: 10.1167/iovs.17-21787.
5. 霍妍佼, 杨丽红, 崔蕊, 等. 共焦激光扫描检眼镜与彩色眼底照相对视网膜和脉络膜病变的检出比较[J]. 中华眼底病杂志, 2016, 32(3): 270-274. DOI: 10.3760/cma.j.issn.1005-1015.2016.03.010.Huo YJ, Yang LH, Cui R, et al. Comparison of confocal scanning laser ophthalmoscope and color fundus camera to assess retinal and choroidal disease using[J]. Chin J Ocul Fundus Dis, 2016, 32(3): 270-274. DOI: 10.3760/cma.j.issn.1005-1015.2016.03.010.
6. 霍妍佼, 郭彦, 杨丽红, 等. 共聚焦激光扫描检眼镜眼底成像与传统眼底彩色照相对老年人黄斑前膜检出结果比较[J]. 中华眼底病杂志, 2016, 32(6): 615-618. DOI: 10.3760/cma.j.issn.1005-1015.2016.06.012.Huo YJ, Guo Y, Yang LH, et al. Comparison of the screening efficiency of epiretinal membrane using confocal scanning laser ophthalmoscope imaging and color fundus camera in elderly people[J]. Chin J Ocul Fundus Dis, 2016, 32(6): 615-618. DOI: 10.3760/cma.j.issn.1005-1015.2016.06.012.
7. Paavo M, Zhao J, Kim HJ, et al. Mutations in GPR143/OA1 and ABCA4 inform interpretations of short-wavelength and near-infrared fundus autofluorescence[J]. Invest Ophthalmol Vis Sci, 2018, 59(6): 2459-2469. DOI: 10.1167/iovs.18-24213.
8. Giani A, Pellegrini M, Carini E, et al. The dark atrophy with indocyanine green angiography in Stargardt disease[J]. Invest Ophthalmol Vis Sci, 2012, 53(7): 3999-4004. DOI: 10.1167/iovs.11-9258.
9. Klufas MA, Tsui I, Sadda SR, et al. Ultrawidefield autofluoresence in ABC4A Stargardt disease[J]. Retina, 2018, 38(2): 403-415. DOI: 10.1097/IAE.0000000000001567.
10. McGuigan DB, Heon E, Cideciyan AV, et al. EYS mutations causing autosomal recessive retinitis pigmentosa: changes of retinal structure and function with disease progression[J/OL]. Genes (Basel), 2017, 8(7): 178[2017-07-12]. https://www.mdpi.com/2073-4425/8/7/178. DOI: 10.3390/genes8070178.
11. 陈伟, 杨文利, 魏文斌, 等. 超声弹性成像对眼内肿瘤的鉴别诊断价值[J]. 肿瘤影像学, 2016, 25(4): 303-307. DOI: 10.3969/j.issn.1008-617X.2016.04.003.Chen W, Yang WL, Wei WB, et al. Value of ultrasonic elastosonography in differential diagnosis of intraocular tumors[J]. Oncoradiology, 2016, 25(4): 303-307. DOI: 10.3969/j.issn.1008-617X.2016.04.003.
12. Balaratnasingam C, Cherepanoff S, Dolz-Marco R, et al. Cuticular drusen: clinical phenotypes and natural history defined using multimodal imaging[J]. Ophthalmology, 2018, 125(1): 100-118. DOI: 10.1016/j.ophtha.2017.08.033.
13. Pedersen HR, Gilson SJ, Dubra A, et al. Multimodal imaging of small hard retinal drusen in young healthy adults[J]. Br J Ophthalmol, 2018, 102(1): 146-152. DOI: 10.1136/bjophthalmol-2017-310719.
14. Verdina T, Greenstein VC, Sodi A, et al. Multimodal analysis of the preferred retinal location and the transition zone in patients with Stargardt disease[J]. Graefe's Arch Clin Exp Ophthalmol, 2017, 255(7): 1307-1317. DOI: 10.1007/s00417-017-3637-6.
15. Pichi F, Veronese C, Lembo A, et al. New appraisals of Kyrieleis plaques: a multimodal imaging study[J]. Br J Ophthalmol, 2017, 101(3): 316-321. DOI: 10.1136/bjophthalmol-2015-308246.
16. Barbazetto I, Dansingani KK, Yannuzzi LA, et al. Idiopathic acute exudative polymorphous vitelliform maculopathy: clinical spectrum and multimodal imaging characteristics[J]. Ophthalmology, 2018, 125(1): 75-88. DOI: 10.1016/j.ophtha.2017.07.020.
17. Williams PJ, Robinson J. Multimodal imaging of presumed ocular manifestations in end-stage diffuse large B-cell lymphoma[J]. Retina, 2017, 37(10): 113-115. DOI: 10.1097/IAE.0000000000001821.
18. Knickelbein JE, Sen HN. Multimodal imaging of the white dot syndromes and related diseases[J/OL]. J Clin Exp Ophthalmol, 2016, 7(3): 570[2016-06-27]. https://www.ncbi.nlm.nih.gov/pubmed/27482471.
19. Pellegrini M, Acquistapace A, Oldani M, et al. Dark atrophy: an optical coherence tomography angiography study[J]. Ophthalmology, 2016, 123(9): 1879-1886.

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