Primary Study on Noninvasive Detection of Vascular Function Based on Finger Temperature Change_Journal of Biomedical Engineering

Authors：

DONGQing ¹ ,  LIXia ^1,2 , WANYungao ³ , LUGaoquan ¹ , WANGXinxin ¹ , ZHANGKuan ^1,2

1. School of Biomedical Engineering, Capital Medical University, Beijing 100069, China;
2. Beijing Key Laboratory of Fundamental Research on Biomechanics in Clinical Application, Capital Medical University, Beijing 100069, China;
3. Xuanwu Hospital, Capital Medical University, Beijing 100069, China;

Corresponding author：

LIXia, Email: xiali@ccmu.edu.cn

Keywords：

system design; vascular function; non-invasive detection; finger temperature

DOI：

10.7507/1001-515.20160026

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By studying the relationship between fingertip temperature changes and arterial function during vascular reactivity test, we established a new non-invasive method for detecting vascular function, in order to provide an assistance for early diagnosis and prevention of cardiovascular diseases. We customized three modules respectively for blood occlusion, measurement of finger temperature and blood oxygen acquisition, and then we established the hardware of data acquisition system. And the software was programmed with Labview. Healthy subjects [group A, n=24, (44.6±9.0) years] and subjects with cardiovascular diseases [group B, n=33, (57.2±9.9) years)] were chosen for the study. Subject's finger temperature, blood oxygen and occlusion pressure of block side during and after unilateral arm brachial artery occlusion were recorded, as well as some other regular physiological indexes. By time-domain analysis, we extracted 12 parameters from fingertip temperature signal, including the initial temperature (T_i), temperature rebound (TR), the time of the temperature recovering to initial status (RIt) and other parameters from the finger temperature signal. We in the experiment also measured other regular physiological body mass index (BMI), systolic blood pressure (SBP), diastiolic blood pressure (DBP) and so on. Results showed that 8 parameters difference between the two group of data were significant. based on the statistical results. A discriminant function of vascular function status was established afterwards. We found in the study that the changes of finger temperature during unilateral arms brachial artery occlusion and open were closely related to vascular function. We hope that the method presented in this article could lay a foundation of early detection of vascular function.

Citation： DONGQing, LIXia, WANYungao, LUGaoquan, WANGXinxin, ZHANGKuan. Primary Study on Noninvasive Detection of Vascular Function Based on Finger Temperature Change. Journal of Biomedical Engineering, 2016, 33(): 144-148. doi: 10.7507/1001-515.20160026 Copy

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1. 张丽艳, 乔磊. 795名国家公务员心血管疾病健康风险评估[J] .中国健康教育统计研究.2003,19(9): 656-658.
2. 孙瑞娟, 朱毅, 汪南平等. 血管病变机制与血管功能调控研究的现状与趋势[J] .中国科学: 生命科学, 2013, 43(2): 103-111.
3. NAGHAVI. cardiohealth methodes and apparatus.Houtston(US).US2012/0065514.A1.Mar.15, 2012.
4. DHINDSA, SOMMERLAD SM, DEVAN AE, LEY O, et al. Interrelationships among noninvasive measures of postischemic macro- and microvascular reactivity[J] Appl Physiol 2008 (105): 427-432.
5. JESSEN C, Temperature Regulation in Humans and Other Mammals, Springer, Berlin, 2000.
6. CHARKOUDIAN N, skin blood flow in adult human thermoregulation:How it works, when it does not, and why, in: Mayo Clinic Proceedings,2003(66):603-612.
7. GUL K M, AHMADI N, WANG Z, et al.Digital thermal monitoring of vascular function: a novel tool to improve cardiovascular risk assessment[J] .Vascular Medicine, 2009, 14(2):143-148.
8. AHMADI N, NABAVI V, NUGURI V. Low fingertip temperature rebound measured by digital thermal monitoring strongly correlates with the presence and extent of coronary artery disease diagnosed by 64-slice multi-detector computed tomography[J] . Cardiovasc Imaging, 2009(25):725-738.

Journal of Biomedical Engineering

Primary Study on Noninvasive Detection of Vascular Function Based on Finger Temperature Change

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