Application of Pencil Beam Model Based on Point Kernel in Intensity Modified Radiatioin Therapy_Journal of Biomedical Engineering

Authors：

 ZOUHao , WANGYu

Sino-Dutch Biomedical and Information Engineering School, Northeastern University, Shenyang 110004, China;

Corresponding author：

ZOUHao, Email: zouh@neusoft.com

Keywords：

intensity optimization theropy; point kernel; dose calculation; pencil beam kernel

DOI：

10.7507/1001-5515.20140033

Video：

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In this paper, a method for dose calculation with pencil beam kernels constructed by point kernel superposition was proposed to accelerate the dose calculation during intensity optimization iteration. With this method, the direct aperture optimization method can be integrated in the planning system based on point kernel convolution/superposition model. The dose calculation time was also reduced during the iteration. From the result of the phantom and clinical patient data test, it was concluded that this method could be used for the intensity optimization of iteration dose calculation as the satisfied precision due to the optimization result coherence obtained. By implementing the method in the planning system product based on point kernel convolution/superposition model, a lot of additional research and development works for the pencil beam dose calculation model as well as the product maintenance cost can be avoided.

Citation： ZOUHao, WANGYu. Application of Pencil Beam Model Based on Point Kernel in Intensity Modified Radiatioin Therapy. Journal of Biomedical Engineering, 2014, 31(1): 166-171. doi: 10.7507/1001-5515.20140033 Copy

1.	胡逸民.肿瘤放射物理学[M].北京:原子能出版社,1999.
2.	SPIROU S V, CHUI C S. A gradient inverse planning algorithm with dose-volume constraints[J]. Med Phys, 1998, 25(3):321-333.
3.	COTRUTZ C, LAHANAS M, KAPPAS C, et al. A multiobjective gradient-based dose optimization algorithm for external beam conformal radiotherapy[J]. Phys Med Biol, 2001, 46(8):2161-2175.
4.	KIRKPATRICK S, GELATT C D JR., VECCHI M P. Optimization by simulated annealing[J]. Science, 1983, 220(4598):671-680.
5.	周明,孙树栋.遗传算法原理及应用[M].北京:国防工业出版社,2002.
6.	GEMAN S, GEMAN D. Stochastic relaxation, gibbs distributions, and the bayesian restoration of images[J]. IEEE Trans Pattern Anal Mach Intell, 6(6):721-741.
7.	OSTAPIAK O Z, ZHU Y, VAN DYK J. Refinements of the finite-size pencil beam model of three-dimensional photon dose calculation[J]. Med Phys, 1997, 24(5):743-750.
8.	MOHAN R, CHUI C, LIDOFSKY L. Differential pencil beam dose computation model for photons[J]. Med Phys, 1986, 13(1):64-73.
9.	MACKIE T R, SCRIMGER J W, BATTISTA J J. A convolution method of calculating dose for 15-MV x rays[J]. Med Phys, 1985, 12(2):188-196.
10.	AHNESJÖ A, ANDREO P, BRAHME A. Calculation and application of point spread functions for treatment planning with high energy photon beams[J]. Acta Oncol, 1987, 26(1):49-56.
11.	PAPANIKOLAOU N, MACKIE T R, MEGER-WELLS C, et al. Investigation of the convolution method for polyenergetic spectra[J]. Med Phys, 1993, 20(5):1327-1336.
12.	BOURLAND J D, CHANEY E L. A finite-size pencil beam model for photon dose calculations in three dimensions[J]. Med Phys, 1992, 19(6):1401-1412.

1. 胡逸民.肿瘤放射物理学[M].北京:原子能出版社,1999.
2. SPIROU S V, CHUI C S. A gradient inverse planning algorithm with dose-volume constraints[J]. Med Phys, 1998, 25(3):321-333.
3. COTRUTZ C, LAHANAS M, KAPPAS C, et al. A multiobjective gradient-based dose optimization algorithm for external beam conformal radiotherapy[J]. Phys Med Biol, 2001, 46(8):2161-2175.
4. KIRKPATRICK S, GELATT C D JR., VECCHI M P. Optimization by simulated annealing[J]. Science, 1983, 220(4598):671-680.
5. 周明,孙树栋.遗传算法原理及应用[M].北京:国防工业出版社,2002.
6. GEMAN S, GEMAN D. Stochastic relaxation, gibbs distributions, and the bayesian restoration of images[J]. IEEE Trans Pattern Anal Mach Intell, 6(6):721-741.
7. OSTAPIAK O Z, ZHU Y, VAN DYK J. Refinements of the finite-size pencil beam model of three-dimensional photon dose calculation[J]. Med Phys, 1997, 24(5):743-750.
8. MOHAN R, CHUI C, LIDOFSKY L. Differential pencil beam dose computation model for photons[J]. Med Phys, 1986, 13(1):64-73.
9. MACKIE T R, SCRIMGER J W, BATTISTA J J. A convolution method of calculating dose for 15-MV x rays[J]. Med Phys, 1985, 12(2):188-196.
10. AHNESJÖ A, ANDREO P, BRAHME A. Calculation and application of point spread functions for treatment planning with high energy photon beams[J]. Acta Oncol, 1987, 26(1):49-56.
11. PAPANIKOLAOU N, MACKIE T R, MEGER-WELLS C, et al. Investigation of the convolution method for polyenergetic spectra[J]. Med Phys, 1993, 20(5):1327-1336.
12. BOURLAND J D, CHANEY E L. A finite-size pencil beam model for photon dose calculations in three dimensions[J]. Med Phys, 1992, 19(6):1401-1412.

Journal of Biomedical Engineering

Application of Pencil Beam Model Based on Point Kernel in Intensity Modified Radiatioin Therapy

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