Development and Validation of a C0-T1 Three-dimensional Finite Element Model of a Healthy Person Under Physiologic Loads_Journal of Biomedical Engineering

Authors：

WANGHuihao ¹ ,  ZHANHongsheng ¹ , CHENBo ² , SHIYinyu ¹ , LILinghui ¹ , DUGuoqing ¹

1. Shi's Center of Orthopedics and Traumatology, Shuguang Hospital Affiliated to Shanghai University of TCM, Institute of Traumatology & Orthopedics, Shanghai Academy of TCM, Shanghai 201203, China;
2. Institute of Orthopaedics and Traumatology, Shanghai 200025, China;

Corresponding author：

ZHANHongsheng, Email: zhanhongsheng2010@163.com

Keywords：

cervical spine; finite element model; biomechanics

DOI：

10.7507/1001-5515.20140235

Video：

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A comprehensive, geometrically accurate, nonlinear C0-T1 three-dimensional finite element (FE) model was developed for the biomechanical study of human cervical spine and related disorders. The model was developed with anatomic detail from the computed tomography (CT) images of a 46-year old female healthy volunteer, and applied the finite element model processing softwares such as MIMICS13.1, Hypermesh11.0, Abaqus 6.12-1, etc., for developing, preprocessing, calculating and analysing sequentially. The stress concentration region and the range of motion (ROM) of each vertebral level under axial rotation, flexion, extension, and lateral bending under physiologic static loadings were observed and recorded. The model was proven reliable, which was validated with the range of motion in previous published literatures. The model predicted the front and side parts of the foramen magnum and contralateral pedicle and facet was the stress concentration region under physiological loads of the upper spine and the lower spine, respectively. The development of this comprehensive, geometrically accurate, nonlinear cervical spine FE model could provide an ideal platform for theoretical biomechanical study of human cervical spine and related disorders.

Citation： WANGHuihao, ZHANHongsheng, CHENBo, SHIYinyu, LILinghui, DUGuoqing. Development and Validation of a C0-T1 Three-dimensional Finite Element Model of a Healthy Person Under Physiologic Loads. Journal of Biomedical Engineering, 2014, 31(6): 1238-1242,1249. doi: 10.7507/1001-5515.20140235 Copy

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1. 詹红生.脊柱整复手法的力学效应研究[J].中国中医骨伤科杂志,2006,14(S2):225-226.
2. 昌耘冰,徐达传,尹庆水.颈椎生物力学模型的应用及进展[J].中国临床解剖学杂志,2003,21(2):187-189.
3. 徐德永,孙锡和.颈椎病发生的解剖学和生物力学基础[J].临床放射学杂志,1997,16(2):120-122.
4. PANJABI M M. Cervical spine models for biomechanical research[J]. Spine[J], 1998, 23(24):2684-2699.
5. ZHANG Q H,TEO E C, NG H W. Development and validation of a C0-C7 FE complex for biomechanical study[J]. J Biomech Eng, 2005, 127(5):729-735.
6. BROLIN K, HALLDIN P. Development of a finite element model of the upper cervical spine and a parameter study of ligament characteristics[J]. Spine (Phila Pa 1976), 2004, 29(4):376-385.
7. TENCER A M, BENSEL K. Internal loads in the cervical spine during motor vehicle rear-end impacts:the effect of acceleration and head-to-head restraint proximity[J]. Spine (Phila Pa 1976), 2002, 27(1):34-42.
8. 陈金水,倪斌,陈博,等.寰枢椎脱位三维非线性有限元模型的建立和分析[J].中国脊柱脊髓杂志,2010,20(9):749-753.
9. ZHANG H, BAI J. Development and validation of a finite element model of the occipito-atlantoaxial complex under physiologic loads[J].Spine (Phila Pa 1976), 2007, 32(9):968-974.
10. VAN C M, HUISKES R.骨科生物力学暨力学生物学[M].济南:山东科学技术出版社,2009:500-503.
11. 贾连顺,袁文.现代脊柱外科学[M].北京:人民军医出版社,2007:21-24.
12. CARTER D R, HAYES W C. The compressive behavior of bone as a two-phase porous structure[J]. J Bone Joint Surg Am, 1977, 59(7):954-962.
13. HALLDIN P. Prevention and prediction of head and neck injury in traffic accidents-using experimental and numerical methods[D]. Stockholm:KTH, 2001.
14. DVORAK J, SCHNEIDER E, SALDINGER P, et al. Biomechanics of the craniocervical region:the alar and transverse ligaments[J]. J Orthop Res, 1988, 6(3):452-461.
15. LEE C K, KIM Y E, LEE C S, et al. Impact response of the intervertebral disc in a finite-element model[J]. Spine (Phila Pa 1976), 2000, 25(19):2431-2439.
16. SCHMIDT H, KETTLER A, HEUER F, et al. Intradiscal pressure, shear strain, and fiber strain in the intervertebral disc under combined loading[J]. Spine (Phila Pa 1976), 2007, 32(7):748-755.
17. HONG-WAN N, EE-CHON T, QING-HANG Z. Biomechanical effects of C2-C7 intersegmental stability due to laminectomy with unilateral and bilateral facetectomy[J]. Spine (Phila Pa 1976), 2004, 29(16):1737-1745.
18. YOGANANDAN N, KUMARESAN S, PINTAR F A. Biomechanics of the cervical spine Part 2. Cervical spine soft tissue responses and biomechanical modeling[J]. Clin Biomech (Bristol, Avon), 2001, 16(1):1-27.
19. PANJABI M M, CRISCO J J, VASAVADA A, et al. Mechanical properties of the human cervical spine as shown by three-dimensional load-displacement curves[J]. Spine (Phila Pa 1976), 2001, 26(24):2692-2700.
20. BOGDUK N, MERCER S. Biomechanics of the cervical spine.Ⅱ:Normal kinematics[J]. Clin Biomch, 2000, 15(9):633-648.
21. 俞大方.推拿学[M].上海:上海科技出版社,1985:3-5.
22. 张明才,詹红生,石印玉,等.基于"骨错缝,筋出槽"诊治椎间盘病症[J].中国骨伤,2008,21(6):441-443.
23. KAWCHUK G N, JHANGRI G S, HURWITZ E L, et al. The relation between the spatial distribution of vertebral artery compromise and exposure to cervical manipulation[J]. J Neurol, 2008, 255(3):371-377.
24. 王辉昊,詹红生,张明才,等.手法治疗颈椎病意外事件分析与预防策略思考[J].中国骨伤,2012,25(9):730-736.
25. 王辉昊,张明才,詹红生.由脊骨神经医学发展模式引发的思考[J].中国骨伤,2011,24(8):662-666.
26. HUSSAIN M, NATARAJAN R N, AN H S, et al. Motion changes in adjacent segments due to moderate and severe degeneration in C5-C6 disc:a poroelastic C3-T1 finite element model study[J]. Spine (Phila Pa 1976), 2010, 35(9):939-947.
27. JOZWIK K, OBIDOWSKI D. Numerical simulations of the blood flow through vertebral arteries[J]. J Biomech, 2010, 43(2):177-185.

Journal of Biomedical Engineering

Development and Validation of a C0-T1 Three-dimensional Finite Element Model of a Healthy Person Under Physiologic Loads

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