Study on a New Urine Analysis Core Module Based on Semi-reflection Mirror_Journal of Biomedical Engineering

Authors：

CHENLongcong ^1,3 , LIUGaiqin ² , HUNan ² , ZHANGRuiying ^1,3 , JIANGQifeng ¹ , GAOBin ^1,3 ,  XIONGXingliang ^1,3

1. Department of Biomedicine Engineering, Chongqing Medical University, Chongqing 400016, China;
2. School of Optoelectronic Information, Chongqing University of Technology, Chongqing 400050, China;
3. Laboratory of Forensic Medicine and Biomedical Information, Chongqing Medical University, Chongqing 400016, China;

Corresponding author：

XIONGXingliang, Email: xxlsober@sina.com

Keywords：

Color sensor; Microprocessor; Urine analysis; Urine reagent strip

DOI：

10.7507/1001-5515.20140244

Video：

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Abstract Full text Figures/Tables Video References Cited by

A new urine analysis core module based on high performance 32-bit microprocessor and high precision color sensor was presented. A novel optical structure and a specific circuit were applied to improve measurement precision and temperature was used to compensate for results in this core module. The information of urine test peice, such as all original data and color RGB value, reflectivity, semi-quantitative level, etc. can be output. The results showed that the measuring precision was about 95% or above with ideal stability and reliability using this presented core module, which can be conveniently applied in various urine analyzers, and can greatly decrease the cost of urine analyzers in development and production.

Citation： CHENLongcong, LIUGaiqin, HUNan, ZHANGRuiying, JIANGQifeng, GAOBin, XIONGXingliang. Study on a New Urine Analysis Core Module Based on Semi-reflection Mirror. Journal of Biomedical Engineering, 2014, 31(6): 1288-1293. doi: 10.7507/1001-5515.20140244 Copy

1.	MOHAN K, DONAVAN K C, ARTER J A, et al. Sub-nanomolar detection of prostate-specific membrane antigen in synthetic urine by synergistic, dual-ligand phage[J]. J Am Chem Soc, 2013, 135(20):7761-7767.
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3.	RUSSELL S J, SOUSA-FIGUEIREDO J C,SIMBA K I, et al. Urinary schistosomiasis-associated morbidity in schoolchildren detected with urine albumin-to-creatinine ratio(UACR)reagent strips[J]. J Pediatr Urol., 2009, 5(4):287-291.
4.	CHANDRA P, SON N X, NOH H B, et al. Investigation on the downregulation of dopamine by acetaminophen administration based on their simultaneous determination in urine[J]. Biosens Bioelectron, 2013, 39(1):139-144.
5.	HORIKOSHI S, HIGURASHI A, KANEKO E, et al. A new screening method for proteinuria using Erythrosin B and an automated analyzer——rapid, sensitive and inexpensive determination[J]. Clin Chim Acta, 2012, 413(13-14):1087-1091.
6.	郝卫东,陈亮,李静.基于μC/OS-Ⅱ的尿液分析仪的设计与实现[J].计算机系统应用,2008,16(12):92-95.
7.	雷亚平,归发弟.基于STC89C516RD的尿液分析仪的设计[J].广西轻工业,2010,26(6):57-58.
8.	马腾,廖海洋,黄宗伟.基于CCD的微小型快速尿液分析仪的设计[J].仪器仪表学报,2007,28(4):8-11.
9.	王春红,周越,赵红霞,等.基于色差评定理论的尿液生化分析方法研究[J].生物医学工程学杂志,2008,25(1):77-82.
10.	王惠中,宿忠娥,默立峰,等.基于Delphi的尿液分析仪应用软件的研究与设计[J].电气自动化,2008,30(5):71-72.
11.	TIGHE P. Urine dry reagent strip "error" rates using different reading methods[J]. Accred Qual Assur, 2000, 5(12):488-490.
12.	焦仁福,臧葳.干化学法尿液分析影响因素探讨[J].中国疗养医学,2013,22(2):180-181.
13.	COSTA C E, BETTENDORFF C, BUPO S, et al. Comparative measurement of urine specific gravity:reagent strips, refractometry and hydrometry[J]. Arch Argent Pediatr, 2010, 108(3):234-238.
14.	王珂.全自动尿液分析仪分析尿液的影响因素探讨[J].中华现代临床医学杂志,2005,3(21):2283-2284.
15.	BOGOCH I I, ANDREWS J R, DADZIE EPHRAIM R K, et al. Simple questionnaire and urine reagent strips compared to microscopy for the diagnosis of Schistosoma haematobium in a community in northern Ghana[J]. Trop Med Int Health, 2012, 17(10):1217-1221.
16.	曹妍.提高尿液分析仪尿常规检测准确性方法的探讨[J].中华保健医学杂志,2010,12(2):140-141.
17.	陈龙聪,刘改琴,刘亚涛,等.基于STM32和USB接口的开放式高性能新型医用信号仪的研制[J].中国生物医学工程学报,2012,31(6):946-950.

1. MOHAN K, DONAVAN K C, ARTER J A, et al. Sub-nanomolar detection of prostate-specific membrane antigen in synthetic urine by synergistic, dual-ligand phage[J]. J Am Chem Soc, 2013, 135(20):7761-7767.
2. 戴群莹,陈向南,吴晓虹.尿液分析在健康体检中的重要性[J].中国疗养医学,2011,20(3):266.
3. RUSSELL S J, SOUSA-FIGUEIREDO J C,SIMBA K I, et al. Urinary schistosomiasis-associated morbidity in schoolchildren detected with urine albumin-to-creatinine ratio(UACR)reagent strips[J]. J Pediatr Urol., 2009, 5(4):287-291.
4. CHANDRA P, SON N X, NOH H B, et al. Investigation on the downregulation of dopamine by acetaminophen administration based on their simultaneous determination in urine[J]. Biosens Bioelectron, 2013, 39(1):139-144.
5. HORIKOSHI S, HIGURASHI A, KANEKO E, et al. A new screening method for proteinuria using Erythrosin B and an automated analyzer——rapid, sensitive and inexpensive determination[J]. Clin Chim Acta, 2012, 413(13-14):1087-1091.
6. 郝卫东,陈亮,李静.基于μC/OS-Ⅱ的尿液分析仪的设计与实现[J].计算机系统应用,2008,16(12):92-95.
7. 雷亚平,归发弟.基于STC89C516RD的尿液分析仪的设计[J].广西轻工业,2010,26(6):57-58.
8. 马腾,廖海洋,黄宗伟.基于CCD的微小型快速尿液分析仪的设计[J].仪器仪表学报,2007,28(4):8-11.
9. 王春红,周越,赵红霞,等.基于色差评定理论的尿液生化分析方法研究[J].生物医学工程学杂志,2008,25(1):77-82.
10. 王惠中,宿忠娥,默立峰,等.基于Delphi的尿液分析仪应用软件的研究与设计[J].电气自动化,2008,30(5):71-72.
11. TIGHE P. Urine dry reagent strip "error" rates using different reading methods[J]. Accred Qual Assur, 2000, 5(12):488-490.
12. 焦仁福,臧葳.干化学法尿液分析影响因素探讨[J].中国疗养医学,2013,22(2):180-181.
13. COSTA C E, BETTENDORFF C, BUPO S, et al. Comparative measurement of urine specific gravity:reagent strips, refractometry and hydrometry[J]. Arch Argent Pediatr, 2010, 108(3):234-238.
14. 王珂.全自动尿液分析仪分析尿液的影响因素探讨[J].中华现代临床医学杂志,2005,3(21):2283-2284.
15. BOGOCH I I, ANDREWS J R, DADZIE EPHRAIM R K, et al. Simple questionnaire and urine reagent strips compared to microscopy for the diagnosis of Schistosoma haematobium in a community in northern Ghana[J]. Trop Med Int Health, 2012, 17(10):1217-1221.
16. 曹妍.提高尿液分析仪尿常规检测准确性方法的探讨[J].中华保健医学杂志,2010,12(2):140-141.
17. 陈龙聪,刘改琴,刘亚涛,等.基于STM32和USB接口的开放式高性能新型医用信号仪的研制[J].中国生物医学工程学报,2012,31(6):946-950.

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