Research on Energy Distribution During Osteoarthritis Treatment Using Shock Wave Lithotripsy_Journal of Biomedical Engineering

Authors：

ZHANGShinian ¹ , WANGXiaofeng ² ,  ZHANGDong ²

1. Massage Department, The Affiliated Hospital of Nanjing University of Chinese Medicine (The Traditional Chinese Medicine Hospital of Jiangsu Province), Nanjing 210023, China;
2. Institute of Acoustics, Nanjing University, Nanjing 210093, China;

Corresponding author：

ZHANGDong, Email: dzhang@nju.edu.cn

Keywords：

extracorporeal shock wave; osteoarthritis; finite element method

DOI：

10.7507/1001-5515.20150055

Video：

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Extracorporeal shock wave treatment is capable of providing a non-surgical and effective treatment modality for patients suffering from osteoarthritis. The major objective of current works is to investigate how the shock wave (SW) field would change if a bony structure exists in the path of the acoustic wave. Firstly, a model of finite element method (FEM) was developed based on Comsol software in the present study. Then, high-speed photography experiments were performed to record cavitation bubbles with the presence of mimic bone. On the basis of comparing experimental with simulated results, the effectiveness of FEM model could be verified. Finally, the energy distribution during extracorporeal shock wave treatment was predicted. The results showed that the shock wave field was deflected with the presence of bony structure and varying deflection angles could be observed as the bone shifted up in the z-direction relative to shock wave geometric focus. Combining MRI/CT scans to FEM modeling is helpful for better standardizing the treatment dosage and optimizing treatment protocols in the clinic.

Citation： ZHANGShinian, WANGXiaofeng, ZHANGDong. Research on Energy Distribution During Osteoarthritis Treatment Using Shock Wave Lithotripsy. Journal of Biomedical Engineering, 2015, 32(2): 300-304. doi: 10.7507/1001-5515.20150055 Copy

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1. 何兆雄, 金艳, 张天民.硫酸软骨素的结构及其在骨关节炎治疗中的应用[J].中国药学杂志, 2012, 47(5):387-391.
2. 孙磊, 刘文勇, 孙晶, 等.关节运动机能学的研究进展[J].生物医学工程学杂志, 2008, 25(6):1458-1461.
3. 李娟红, 程斌, 李桂英.冲击波配合跖腱膜牵拉训练治疗顽固性跟痛症的疗效研究[J].中国康复医学杂志, 2012, 27(9):854-856.
4. ROMEO P, LAVANGA V, PAGANI D, et al. Extracorporeal shock wave therapy in musculoskeletal disorders:a review[J]. Med Princ Pract, 2014, 23(1):7-13.
5. HA C H, KIM S, CHUNG J, et al. Extracorporeal shock wave stimulates expression of the angiogenic genes via mechanosensory complex in endothelial cells:mimetic effect of fluid shear stress in endothelial cells[J]. Int J Cardiol, 2013, 168(4):4168-4177.
6. PEREZ C, CHEN H, MATULA T J, et al. Acoustic field characterization of the Duolith:measurements and modeling of a clinical shock wave therapy device[J]. J Acoust Soc Am, 2013, 134(2):1663-1674.
7. CHAO Y H, TSUANG Y H, SUN J S, et al. Effects of shock waves on tenocyte proliferation and extracellular matrix metabolism[J]. Biol, 2008, 34(5):841-852.
8. 陶泉, 杜青.体外冲击波治疗骨质疏松症研究进展[J].中国康复, 2011, 26(1):61-62.
9. YILMAZ B, ÇIFTÇI E. An FDTD-based computer simulation platform for shock wave propagation in electrohydraulic lithotripsy[J]. Comput Methods Programs Biomed, 2013, 110(3):389-398.
10. 樊黎霞, 丁光兴, 费王华, 等.基于CT图像的长管骨有限元材料属性研究及实验验证[J].医用生物力学, 2012, 27(1):102-108.
11. SOKOLOV D L, BAILEY M R, CRUM L A, et al. Prefocal alignment improves stone comminution in shockwave lithotripsy[J]. J Endourol, 2002, 16(10):709-715.

Journal of Biomedical Engineering

Research on Energy Distribution During Osteoarthritis Treatment Using Shock Wave Lithotripsy

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