Cool-tip Radiofrequency Ablation Therapy Instrument Based on Impedance Control Algorithm_Journal of Biomedical Engineering

Authors：

 ZHENGDanping ¹ , ZHUMingri ¹ , LIUWenbin ² , YAOXin ² , PANKai ² , GONGHuibin ³

1. School of Computer Science and Engineering, Guilin University of Electronic Technology, Guilin 541004, China;
2. School of Electronic Engineering and Automation, Guilin University of Electronic Technology, Guilin 541004, China;
3. Zhuhai Hokai Medical Instruments Co., Ltd, Zhuhai 519030, China;

Corresponding author：

ZHENGDanping, Email: clovezdp@126.com

Keywords：

radiofrequency ablation; cool-tip radiofrequency ablation therapeutic instrument; impedance control algorithm; real-time curve display

DOI：

10.7507/1001-5515.20150161

Video：

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Abstract Full text Figures/Tables Video References Cited by

A new cool-tip radiofrequency (RF) ablation therapeutic instrument based on impedance control algorithm is introduced in this paper. The equipment is composed of hardware system and software system. The RF power output and real time data acquisition are completed by the hardware system, while the software is used mainly to finish the control of the ablation range, the core of which is impedance control algorithm, and it also used to complete the display of the real time data in the course of the experiment. The impedance algorithm has solved the problem of impedance increased rapidly during the RF ablation, which has also expanded the scope of ablation. The pig liver experiments showed that the impedance control algorithm had strong adaptability. It also obtained a result of ablation range up to 3.5~4.5 cm single needle. It has the high clinical practical value of one-time inactivation of 3~5 cm tumor.

Citation： ZHENGDanping, ZHUMingri, LIUWenbin, YAOXin, PANKai, GONGHuibin. Cool-tip Radiofrequency Ablation Therapy Instrument Based on Impedance Control Algorithm. Journal of Biomedical Engineering, 2015, 32(4): 905-909. doi: 10.7507/1001-5515.20150161 Copy

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1. 赖子森,崔永良,沈聪龙,等.射频消融术在原发性小肝癌治疗中的应用[J].中国普通外科杂志,2012,21(7):905-907.
2. 梁惠宏,彭振维,陈敏山,等.两种射频消融模式联合治疗肝脏恶性肿瘤的疗效分析[J].癌症,2010,29(4):448-452.
3. 翟博,陈夷,李晓燕,等.原发性肝癌射频消融后肿瘤残留分析[J].中华肝胆外科杂志,2009,15(4):254-258.
4. 任国欣,白景峰,沈国峰,等.水冷式单针射频热消融系统可消融范围测定的实验研究[J].中华物理医学与康复杂志,2011,33(6):417-421.
5. 徐晓菲,白景峰,陈亚珠.水冷式射频消融过程中水冷温度对热损伤的影响[J].北京生物医学工程,2008,27(4):393-395.
6. 毛光金,沈林勇,张煜辉,等.生物电阻抗测量实验的设计与研究[J].工业控制计算机,2014,27(1):57-58,60.
7. 戴良图,杨晓玉.温度控制和功率控制射频消融治疗子宫肌瘤临床研究[J].中国妇产科临床杂志,2007,8(5):339-342.
8. 罗洪艳,黄维,潘进洪,等.射频消融建模仿真的研究进展[J].激光杂志,2014,35(1):1-4.
9. HAEMMERICH D.Mathematical modeling of impedance controlled radiofrequency tumor ablation and ex-vivo validation[C].2010 Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).Buenos Aires:2010:1605-1608.
10. KESHTKAR A,MESBAHI A,MEHNATI P.The effect of bladder volume changes on the measured electrical impedance of the urothelium[J].Int J Biomed Eng Technol,2008,1(3):287-293.
11. 梁超英,钱志余.人体组织传热及应用研究[J].生物医学工程研究,2007,26(2):212-215.
12. 苌飞霸,尹军,颜乐先,等.基于生物电阻抗法的人体成分测量系统的研究与评价[J].中国医学物理学杂志,2014,31(2):4833-4838.

Journal of Biomedical Engineering

Cool-tip Radiofrequency Ablation Therapy Instrument Based on Impedance Control Algorithm

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