Control System Design and Test of Digital Comprehensive Training Treadmill for Rats_Journal of Biomedical Engineering

Authors：

 XUXiulin , MAGuanpo , ZHAOJun , HUXiufang

School of Medical Instrument and Food Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China;

Corresponding author：

XUXiulin, Email: xxlin100@163.com

Keywords：

animal treadmill; rat; balance training; exercise training; control system

DOI：

10.7507/1001-5515.20150219

Video：

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This article presents the design of a treadmill of comprehensive training experiment for rats. The treadmill is composed of six tracks and two of them were designed as conventional plane, two were designed to swing right and left, and two were designed to swing back and forth. The power was provided by six motors. The MSP430F149 is used as core to adjust the swing rate and the grade of electric shock. The IAR for MSP430 is used to design the software. The speed of the six tracks could be adjusted between 0 and 30 m/min. The swing tracks of back and forth can be swung for 3-25 times per minute and the swing tracks of right and left for 3-32 times. The electric shock can be divided into three levels, i.e. strong, middle, and weak level for each track. The digital comprehensive training treadmill can meet different training needs, and provide experimental data for mechanism research of some related diseases.

Citation： XUXiulin, MAGuanpo, ZHAOJun, HUXiufang. Control System Design and Test of Digital Comprehensive Training Treadmill for Rats. Journal of Biomedical Engineering, 2015, 32(6): 1233-1238. doi: 10.7507/1001-5515.20150219 Copy

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1. 朱镛连.脑卒中康复与神经康复机制[J].中国康复理论与实践, 2003, 9(3):129-132.
2. 赵仁清.运动影响骨代谢的OPG/RANKL/RANK作用机制[J].体育与科学, 2010, 31(3):76-80.
3. 张靓, 刘小园, 杨洪涛.跑台运动对比目鱼肌和腓肠肌肌肉生长抑制素表达的影响[J].沈阳体育学院学报, 2012, 31(5):73-75, 88.
4. 姚璐, 张缨, 张连峰.跑台运动在动物实验研究中的应用[J].中国比较医学杂志, 2010, 20(6):75-81.
5. DE LEON R D, ACOSTA C N. Effect of robotic-assisted treadmill training and chronic quipazine treatment on hindlimb stepping in spinally transected rats[J]. J Neurotrauma, 2006, 23(7):1147-1163.
6. 姜军庆, 徐琦, 周厚伦, 等.多功能动物减重训练跑台的研制[J].中国生物医学工程学报, 2010, 29(6):869-876.
7. 屠文展, 姜穗, 蒋松鹤.大鼠水中跑台:中国, ZL200920112209.1[P].2009-11-11.
8. 王晨光, 孙运强, 许鸿鹰.步进电机的单片机控制设计分析[J].国外电子测量技术, 2008, 27(9):39-41, 60.
9. 胡大可.MSP430系列单片机C语言程序设计与开发[M].北京:北京航空航天大学出版社, 2003.
10. 沈夏锋, 胡永善.颅脑外伤动物模型及运动康复治疗的研究进展[J].中国脑血管病杂志, 2012, 9(6):327-330.
11. 曾贵刚, 李峻, 张申, 等.fMRI结合神经症状评分评价运动疗法对大鼠局灶性缺血模型的疗效[J].实验动物与比较医学, 2011, 31(4):236-241.
12. 何曼.跑台运动对脑梗死大鼠梗死组织Toll样受体4信号通路的影响[D].沈阳:中国医科大学, 2011.
13. VAN DER BORGHT K, KÓBOR-NYAKAS D E, KLAUKE K, et al. Physical exercise leads to rapid adaptations in hippocampal vasculature:temporal dynamics and relationship to cell proliferation and neurogenesis[J]. Hippocampus, 2009, 19(10):928-936.
14. VAYNMAN S, YING Z, GOMEZ-PINILLA F. Interplay between brain-derived neurotrophic factor and signal transduction modulators in the regulation of the effects of exercise on synaptic-plasticity[J]. Neuroscience, 2003, 122(3):647-657.

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