A simulation of microwave brain imaging of hemorrhagic stroke detection_Journal of Biomedical Engineering

Authors：

CHEN Tianqi ^1,2,3 ,  YANG Hao ^1,2,4 , DU Zebao ^1,2 , DAI Zhiwei ^1,2 , ZENG Wenyi ^1,2,3 , CAI Chang ^1,2,3

1. R&D Center of HealthCare Electronics, Institute of Microelectronics of Chinese Academy of Sciences, Beijing 100029, P.R.China;
2. Beijing Key Laboratory of Radio Frequency IC Technology for Next Generation Communications, Institute of Microelectronics of Chinese Academy of Sciences, Beijing 100029, P.R.China;
3. School of Electronic, Electrical and Communication Engineering, University of Chinese Academy of Sciences, Beijing 101400, P.R.China;
4. Division of Biochip Technology, School of Future Technology, University of Chinese Academy of Sciences, Beijing 101400, P.R.China;

Corresponding author：

YANG Hao, Email: yanghao@ime.ac.cn

Keywords：

hemorrhagic stroke; ultra-wideband microwave technology; medical imaging

DOI：

10.7507/1001-5515.201607032

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This paper describes a simulation of microwave brain imaging for the detection of hemorrhagic stroke. Firstly, in the research process, the formula of DebyeⅡwas used to study tissues of brain and blood clot so that microwave frequency band was confirmed for imaging. Then a model with electromagnetic characteristics of brain was built on this basis. In addition, an ultra-wideband (UWB) Vivaldi antenna is designed to use for transmitting and receiving microwave signals of widths 1.7 GHz to 4 GHz. Microwave signals were transmitted and received when the antenna revolved around the brain model. Symmetric position de-noising method was used to eliminate the strong background noise signals, and finally confocal imaging method was applied to get brain imaging. Blood clot was distinguished clearly from result of imaging and position error was less than 1 cm.

Citation： CHEN Tianqi, YANG Hao, DU Zebao, DAI Zhiwei, ZENG Wenyi, CAI Chang. A simulation of microwave brain imaging of hemorrhagic stroke detection. Journal of Biomedical Engineering, 2017, 34(3): 357-364. doi: 10.7507/1001-5515.201607032 Copy

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2.	WHO. The top 10 leading causes of death. Geneva, Switzerland: World Health Organization, 2008.
3.	Sun Haixin, Zou Xinying, Liu Liping. Epidemiological factors of stroke: a survey of the current status in China. Journal of stroke, 2013, 15(2): 109-114.
4.	宇传华, 罗丽莎, 李梅, 等. 从全球视角看中国脑卒中疾病负担的严峻性. 公共卫生与预防医学, 2016, 27(1): 1-5.
5.	王陇德. 中国脑卒中防治报告. 北京: 中国协和医科大学出版社, 2015.
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8.	Mustafa S, Mohammed B, Abbosh A. Novel preprocessing techniques for accurate microwave imaging of human brain. IEEE Antennas Wirel Propag Lett, 2013, 12(2): 460-463.
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10.	Jalilvand M, Zwick T, Wiesbeck W, et al. UWB synthetic aperture-based radar system for hemorrhagic head-stroke detection// 2011 IEEE Radar Conference(RADAR), 23-27 May 2011. Kansas City, USA: IEEE, 2011: 956-959.
11.	Gabriel S, Lau R W, Gabriel C. The dielectric properties of biological tissues: Ⅲ. Parametric models for the dielectric spectrum of tissues. Phys Med Biol, 1996, 41(11): 2271-2293.
12.	Gabriel S, Lau R W, Gabriel C. The dielectric properties of biological tissues: Ⅱ. Measurements in the frequency range 10 Hz to 20 GHz. Phys Med Biol, 1996, 41(11): 2251-2269.
13.	谢处方, 饶克谨. 电磁场与电磁波. 第 4 版. 北京: 高等教育出版社, 2006.
14.	彭飞. 应用 MRI 探讨大脑正常老化过程中灰质体积改变的研究. 石家庄: 河北医科大学, 2013.
15.	刘海静. 正常脑老化中脑白质改变的 MRI 研究. 石家庄: 河北医科大学, 2014.
16.	Gibson P J. The Vivaldi Aerial// The 9th European Microwave Conference (EuMC), 17-20 Sept 1979. Brighton, UK: EuMA, 1979: 101-105.
17.	尚茨. 超宽带(UWB)天线原理与设计. 北京: 人民邮电出版社, 2012.
18.	Schantz H G. System and method for directional transmission and reception of signals: US, US 20060049991 A1. 2006-03-09.
19.	陈杰. MATLAB 宝典(第 4 版). 北京: 电子工业出版社, 2013.

1. 王维治, 罗祖明. 神经病学. 北京: 人民卫生出版社, 2001.
2. WHO. The top 10 leading causes of death. Geneva, Switzerland: World Health Organization, 2008.
3. Sun Haixin, Zou Xinying, Liu Liping. Epidemiological factors of stroke: a survey of the current status in China. Journal of stroke, 2013, 15(2): 109-114.
4. 宇传华, 罗丽莎, 李梅, 等. 从全球视角看中国脑卒中疾病负担的严峻性. 公共卫生与预防医学, 2016, 27(1): 1-5.
5. 王陇德. 中国脑卒中防治报告. 北京: 中国协和医科大学出版社, 2015.
6. 路鹤晴, 朱国英, 卓维海, 等. 医用 X 射线 CT 辐射剂量影响因素研究//2008 年上海市医学会影像技术专科分会第二届年会论文集. 上海, 2008: 93-96.
7. Abbosh A. Microwave-based system using directional wideband antennas for head imaging// 2014 International Workshop on Antenna Technology: "Small Antennas, Novel EM Structures and Materials, and Applications" (iWAT). Sydney, Australia: CSIRO, 2014: 292-295.
8. Mustafa S, Mohammed B, Abbosh A. Novel preprocessing techniques for accurate microwave imaging of human brain. IEEE Antennas Wirel Propag Lett, 2013, 12(2): 460-463.
9. Jalilvand M, Li X, Zwick T, et al. Hemorrhagic stroke detection via UWB medical imaging// Proceedings of the 5th European Conference on Antennas and Propagation (EUCAP), 10-15 April 2011. Rome, Italy: EurAAP, 2011: 2911-2914.
10. Jalilvand M, Zwick T, Wiesbeck W, et al. UWB synthetic aperture-based radar system for hemorrhagic head-stroke detection// 2011 IEEE Radar Conference(RADAR), 23-27 May 2011. Kansas City, USA: IEEE, 2011: 956-959.
11. Gabriel S, Lau R W, Gabriel C. The dielectric properties of biological tissues: Ⅲ. Parametric models for the dielectric spectrum of tissues. Phys Med Biol, 1996, 41(11): 2271-2293.
12. Gabriel S, Lau R W, Gabriel C. The dielectric properties of biological tissues: Ⅱ. Measurements in the frequency range 10 Hz to 20 GHz. Phys Med Biol, 1996, 41(11): 2251-2269.
13. 谢处方, 饶克谨. 电磁场与电磁波. 第 4 版. 北京: 高等教育出版社, 2006.
14. 彭飞. 应用 MRI 探讨大脑正常老化过程中灰质体积改变的研究. 石家庄: 河北医科大学, 2013.
15. 刘海静. 正常脑老化中脑白质改变的 MRI 研究. 石家庄: 河北医科大学, 2014.
16. Gibson P J. The Vivaldi Aerial// The 9th European Microwave Conference (EuMC), 17-20 Sept 1979. Brighton, UK: EuMA, 1979: 101-105.
17. 尚茨. 超宽带(UWB)天线原理与设计. 北京: 人民邮电出版社, 2012.
18. Schantz H G. System and method for directional transmission and reception of signals: US, US 20060049991 A1. 2006-03-09.
19. 陈杰. MATLAB 宝典(第 4 版). 北京: 电子工业出版社, 2013.

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A simulation of microwave brain imaging of hemorrhagic stroke detection

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