Numerical simulation of the effect of virtual stent release pose on the expansion results_Journal of Biomedical Engineering

Authors：

LI Jing ¹ , PENG Kun ¹ , CUI Xinyang ¹ , FU Wenyu ² ,  QIAO Aike ¹

1. College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, P.R.China;
2. College of Mechanical and Electrical Engineering, Beijing Union University, Beijing 100020, P.R.China;

Corresponding author：

QIAO Aike, Email: qak@bjut.edu.cn

Keywords：

finite element analysis; endovascular stent; numerical simulation; mechanical properties

DOI：

10.7507/1001-5515.201703013

Video：

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Abstract Full text Figures/Tables Video References Cited by

The current finite element analysis of vascular stent expansion does not take into account the effect of the stent release pose on the expansion results. In this study, stent and vessel model were established by Pro/E. Five kinds of finite element assembly models were constructed by ABAQUS, including 0 degree without eccentricity model, 3 degree without eccentricity model, 5 degree without eccentricity model, 0 degree axial eccentricity model and 0 degree radial eccentricity model. These models were divided into two groups of experiments for numerical simulation with respect to angle and eccentricity. The mechanical parameters such as foreshortening rate, radial recoil rate and dog boning rate were calculated. The influence of angle and eccentricity on the numerical simulation was obtained by comparative analysis. Calculation results showed that the residual stenosis rates were 38.3%, 38.4%, 38.4%, 35.7% and 38.2% respectively for the 5 models. The results indicate that the pose has less effect on the numerical simulation results so that it can be neglected when the accuracy of the result is not highly required, and the basic model as 0 degree without eccentricity model is feasible for numerical simulation.

Citation： LI Jing, PENG Kun, CUI Xinyang, FU Wenyu, QIAO Aike. Numerical simulation of the effect of virtual stent release pose on the expansion results. Journal of Biomedical Engineering, 2018, 35(2): 214-218. doi: 10.7507/1001-5515.201703013 Copy

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21.	林峰, 刘祥坤, 黄男男, 等. 基于有限元技术的镍钛金属支架的优化设计. 中国医疗器械杂志, 2014, 38(2): 98-101.
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23.	LaDisa J F, Jr, Olson L E, Guler I, et al. Stent design properties and deployment ratio influence indexes of wall shear stress: a three-dimensional computational fluid dynamics investigation within a normal artery. J Appl Physiol, 2004, 97(1): 424-430.
24.	李景植, 华扬贾, 凌云, 等. 超声评估椎动脉起始段支架置人后残余狭窄及支架位置对其的影响. 中国脑血管病杂志, 2012, 9(11): 577-580.

1. 胡大一, 施仲伟. 心血管疾病防治的新证据、新目标和新策略——美国心脏学院 2005 年科学大会热点报道. 中华医学杂志, 2005, 85(17): 1222-1223.
2. Lim S S, Gaziano T A, Gakidou E, et al. Prevention of cardiovascular disease in high-risk individuals in low-income and middle-income countries: health effects and costs. The Lancet, 2007, 370(964): 2054-2062.
3. Wu W, Petrini L, Gastaldi D, et al. Finite element shape optimization for biodegradable magnesium alloy stents. Ann Biomed Eng, 2010, 38(9): 2829-2840.
4. Whitcher F D. Simulation of in vivo loading conditions of nitinol vascular stent structures. Comput Struct, 1997, 64(5/6): 1005-1011.
5. Walke W, Paszenda Z, Filipiak J. Experimental and numerical biomechanical analysis of vascular stent. J Mater Process Technol, 2005, 164–165: 1263-1268.
6. Migliavacca F, Petrini L, Montanari V, et al. A predictive study of the mechanical behaviour of coronary stents by computer modelling. Med Eng Phys, 2005, 27(1): 13-18.
7. Migliavacca F, Petrini L, Colombo M, et al. Mechanical behavior of coronary stents investigated through the finite element method. J Biomech, 2002, 35(6): 803-811.
8. Auriccho F, Di Loreto M, Sacco E. Finite element analysis of a stenotic artery revascularization through a stent insertion. Comput Methods Biomech Biomed Engin, 2001, 4(3): 249-263.
9. Zahedmanesh H, Kelly D J, Lally C. Simulation of a balloon expandable stent in a realistic coronary artery-determination of the optimum modelling strategy. J Biomech, 2010, 43(11): 2126-2132.
10. Takashima K, Kitou T, Mori K, et al. Simulation and experimental observation of contact conditions between stents and artery models. Med Eng Phys, 2007, 29(3): 326-335.
11. Wu Wei, Wang Weiqiang, Yang Dazhi, et al. Stent expansion in curved vessel and their interactions: A finite element analysis. J Biomech, 2007, 40(11): 2580-2585.
12. 徐江, 杨杰, 杨基, 等. 基于医学影像学的心血管支架力学性能分析. 西南交通大学学报, 2016, 51(1): 201-208.
13. 李红霞, 张艺浩, 王希诚. 基于有限元模拟的支架扩张、血流动力学及支架疲劳分析. 医用生物力学, 2012, 27(2): 178-185.
14. Gu Linxia, Zhao Shijia, Muttyam A K, et al. The relation between the arterial stress and restenosis rate after coronary stenting. J Med Device, 2010, 4(3): 1-7.
15. 王文雯, 冯海全, 王晓, 等. 不锈钢冠脉支架体外耦合扩张变形行为研究. 生物医学工程学杂志, 2013, 30(5): 1027-1032.
16. 冯海全, 孙丽丽, 韩青松, 等. 狭窄血管内支架变形行为及力学性能模拟研究. 功能材料, 2015, 46(22): 22085-22089, 22094.
17. Huang Yuan, Teng Zhongzhao, Sadat U, et al. The influence of computational strategy on prediction of mechanical stress in carotid atherosclerotic plaques: Comparison of 2D structure-only, 3D structure-only, one-way and fully coupled fluid-structure interaction analyses. J Biomech, 2014, 47(6): 1465-1471.
18. Holzapfel G A, Mulvihill J J, Cunnane E M. Computational approaches for analyzing the mechanics of atherosclerotic plaques: A review. J Biomech, 2014, 47(4, SI): 859-869.
19. Conway C, McGarry J P, McHugh P E. Modelling of atherosclerotic plaque for use in a computational test-bed for stent angioplasty. Ann Biomed Eng, 2014, 42(12): 2425-2439.
20. 任庆帅, 任希力, 彭坤, 等. 血管支架在真实狭窄血管模型中扩张过程的模拟研究. 医用生物力学, 2015, 30(6): 488-494.
21. 林峰, 刘祥坤, 黄男男, 等. 基于有限元技术的镍钛金属支架的优化设计. 中国医疗器械杂志, 2014, 38(2): 98-101.
22. Li Hongxia, Qiu Tianshuang, Zhu Bao, et al. Design optimization of coronary stent based on finite element models. Scientific World Journal, 2013, 2013(5): 630243.
23. LaDisa J F, Jr, Olson L E, Guler I, et al. Stent design properties and deployment ratio influence indexes of wall shear stress: a three-dimensional computational fluid dynamics investigation within a normal artery. J Appl Physiol, 2004, 97(1): 424-430.
24. 李景植, 华扬贾, 凌云, 等. 超声评估椎动脉起始段支架置人后残余狭窄及支架位置对其的影响. 中国脑血管病杂志, 2012, 9(11): 577-580.

Journal of Biomedical Engineering

Numerical simulation of the effect of virtual stent release pose on the expansion results

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