Finite element analysis method and optimization of flexible ginger moxibustion based on Abaqus and Taguchi method_Journal of Biomedical Engineering

Authors：

LU Qing ¹ ,  SUN Zhijun ¹ , YANG Jianlin ¹ , QIAN Feng ¹ , GUO Yu ²

1. State Key Laboratory of Mechanics and Control of Mechanical Structures, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, P. R. China;
2. School of Mechatronic Engineering, Jinling Institute of Technology, Nanjing 211169, P. R. China;

Corresponding author：

SUN Zhijun, Email: meezjsun@nuaa.edu.cn

Keywords：

Flexible ginger paste box; Finite element; Waist soft tissue; Equivalent contact area; Taguchi method

DOI：

10.7507/1001-5515.202105012

Video：

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Ginger moxibustion has the effect of regulating zang-fu organs and activating qi and blood circulation. When used, ginger paste is required to be close to human skin. Currently, the ginger box used clinically in the hospital can't meet the requirement of large area fitting human skin, and the efficacy of ginger moxibustion is significantly reduced. In this study, a flexible ginger paste box was proposed, which was composed of flexible components polydimethylsiloxane (PDMS), spring and wire netting. The large flexibility of the structure made it fit well with human skin. Finite element method was used to study the fitting degree between ginger paste box and waist soft tissue. Finite element models of flexible ginger paste box and waist soft tissue were established based on Hypermesh and Abaqus software. The equivalent contact area between the flexible ginger paste box and waist was obtained by numerical simulation under different PDMS unilateral thickness, spring wire diameter, wire netting diameter and ginger paste layer thickness. The four parameters were taken as the influencing factors, and the equivalent contact area was taken as the optimization objective. The typical value analysis and variance analysis of S/N were performed by Taguchi method, and the results showed that among the four influencing factors, the wire netting diameter had the largest influence on equivalent contact area and its contribution rate reached 41.98%. The contribution rates of PDMS unilateral thickness, spring wire diameter and ginger paste layer thickness reached 36.48%, 13.97% and 6.50%, respectively. The optimized PDMS unilateral thickness, spring wire diameter, wire netting diameter and ginger paste layer thickness were 1.5, 0.4, 0.15, 35 mm, respectively, and the equivalent contact area was 95.60 cm². The optimized flexible ginger paste box with great fitting performance can improve the effect of ginger moxibustion.

Citation： LU Qing, SUN Zhijun, YANG Jianlin, QIAN Feng, GUO Yu. Finite element analysis method and optimization of flexible ginger moxibustion based on Abaqus and Taguchi method. Journal of Biomedical Engineering, 2022, 39(2): 380-389. doi: 10.7507/1001-5515.202105012 Copy

1.	黄凯裕, 梁爽, 孙征, 等. 艾灸温通效应的启动机制分析. 中国针灸, 2017, 37(9): 1023-1026.
2.	李莹, 孙超, 邝九杰, 等. 艾灸过程生物组织的传热特性实验研究. 工程热物理学报, 2018, 39(1): 150-154.
3.	朱现民, 隔姜泥重灸法的临证应用. 中国针灸, 2013, 33(3): 233-235.
4.	阚丽娜. 针刺结合隔姜灸治疗腰椎间盘突出症的临床研究. 广州: 广州中医药大学, 2017.
5.	陈利. 热敏灸加铺药隔姜灸联合温针灸治疗脾肾阳虚泄泻27例. 中医研究, 2020, 33(10): 64-67.
6.	路玫, 张丽繁, 袁晔,等. 隔姜灸、悬灸对不同穴位各时段热感度的对比研究. 中国针灸, 2011, 31(3): 232-235.
7.	张振军, 李阳, 廖振华, 等. 有限元法在腰椎生物力学应用中的研究进展和展望. 生物医学工程学杂志, 2016, 33(6): 1196-1202.
8.	夏永莉. 温和灸热传递数学物理模型的分析与建立. 广州: 广州中医药大学, 2008.
9.	贲定严. 艾灸生物传热物理学特性及穴位组织中温度场传播过程仿真研究. 长沙: 湖南中医药大学, 2018.
10.	张琳琳, 王旭义, 陈晓东. Bernese髋臼周围截骨术术前规划的有限元分析方法研究. 生物医学工程学杂志, 2016, 33(3): 455-460.
11.	张英会, 刘辉航, 王德成. 弹簧手册. 北京: 机械工业出版社, 2017: 993-994.
12.	Mooney M. A theory of large elastic deformation. J Appl Phys, 1940, 11(9): 582-592.
13.	Rivlin R S. Large elastic deformations of isotropic materials. I. Fundamental concepts. Philos Trans R Soc A Math Phys Sci, 1948, 240(822): 459-490.
14.	Treloar L R G. The elasticity of a network of long-chain molecules. I/II. Trans Faraday Soc, 1946, 42(4): 83-94.
15.	Ogden R W. Large deformation isotropic elasticity–on the correlation of theory and experiment for incompressible rubberlike solids. Proc Math Phys Eng Sci, 1972, 326(1567): 565-584.
16.	Yeoh O H. Some forms of the strain energy function for rubber. Rubber Chem Technol, 1993, 66(5): 754-771.
17.	Limjeerajarus N, Fakkao M, Lampang S N, et al. Experimental data on mechanical behavior and numerical data on tensile stress distribution of a hyperelastic Polydimethysiloxane (PDMS) based membrane for cell culture. Data Brief, 2020, 30: 105476.
18.	刘鹏. 活体状态下人脸皮肤力学性能实验研究. 天津: 天津大学, 2017.
19.	Hendriks F M, Brokken D, Oomens C W J, et al. The relative contributions of different skin layers to the mechanical behavior of human skin in vivo using suction experiments. Med Eng Phys, 2006, 28(3): 259-266.
20.	刘今越, 顾立振, 郭士杰, 等. 人体舒适度及翻身高度与各部位压力分布研究. 机械设计与制造, 2019(9): 30-34.
21.	Payne T, Mitchell S, Bibb R, et al. The evaluation of new multi-material human soft tissue simulants for sports impact surrogates. J Mech Behav Biomed, 2015, 41: 336-356.
22.	刘鹏, 王世斌, 李林安, 等. 活体状态下人脸皮肤力学性能原位测量研究. 实验力学, 2017, 32(3): 295-304.
23.	Allaire P E, Thacker J G, Edlich R F, et al. Finite deformation theory for in vivo human skin. J Bioeng, 1977, 1(3): 239-249.
24.	Moes N C C M, Horvath I. Finite elements model of the human body: Geometry and non-linear material properties// Proceedings of the TMCE 2002. Wuhan: Huazhong University of Science and Technology, 2002: 477-493.
25.	Bischoff J E, Arruda E M, Grosh K. Finite element modeling of human skin using an isotropic, nonlinear elastic constitutive model. J Biomech, 2000, 33(6): 645-652.
26.	孔祥清, 曲艳东, 章文姣, 等. 蚊子口针刺入皮肤的刺入力分析. 科技导报, 2013, 31(22): 60-63.
27.	Metha A K, Wong F. Measurement of flammability and burn potential of fabrics. Cambridge: Fuels Research Laboratory, MIT, 1973.
28.	侯俊杰. 微针阵列刺入皮肤的理论与实验研究. 大连: 大连理工大学, 2013.
29.	Gerling G J, Thomas G W. The effect of fingertip microstructures on tactile edge perception// First Joint Eurohaptics Conference and Symposium on Haptic Interfaces for Virtual Environment and Teleoperator Systems. World Haptics Conference. Pisa: IEEE, 2005: 63-72.
30.	董凤怡, 宋景艳, 赵晓梅, 等. 铺药隔姜灸治疗急性卡他性中耳炎25例. 中国针灸, 2017, 37(12): 1353-1354.
31.	范强芳, 王凤英, 李灿华, 等. 中药隔姜八髎灸治疗中重度原发性痛经临床研究. 针灸临床杂志, 2020, 36(6): 51-55.
32.	胡金明. 针织内衣接触舒适性研究. 上海: 东华大学, 2016.
33.	赵伟, 储满生, 汤雅婷, 等. 基于田口法的钒钛磁铁矿热压块抗压强度的优化. 东北大学学报(自然科学版), 2015, 36(10): 1441-1442.

1. 黄凯裕, 梁爽, 孙征, 等. 艾灸温通效应的启动机制分析. 中国针灸, 2017, 37(9): 1023-1026.
2. 李莹, 孙超, 邝九杰, 等. 艾灸过程生物组织的传热特性实验研究. 工程热物理学报, 2018, 39(1): 150-154.
3. 朱现民, 隔姜泥重灸法的临证应用. 中国针灸, 2013, 33(3): 233-235.
4. 阚丽娜. 针刺结合隔姜灸治疗腰椎间盘突出症的临床研究. 广州: 广州中医药大学, 2017.
5. 陈利. 热敏灸加铺药隔姜灸联合温针灸治疗脾肾阳虚泄泻27例. 中医研究, 2020, 33(10): 64-67.
6. 路玫, 张丽繁, 袁晔,等. 隔姜灸、悬灸对不同穴位各时段热感度的对比研究. 中国针灸, 2011, 31(3): 232-235.
7. 张振军, 李阳, 廖振华, 等. 有限元法在腰椎生物力学应用中的研究进展和展望. 生物医学工程学杂志, 2016, 33(6): 1196-1202.
8. 夏永莉. 温和灸热传递数学物理模型的分析与建立. 广州: 广州中医药大学, 2008.
9. 贲定严. 艾灸生物传热物理学特性及穴位组织中温度场传播过程仿真研究. 长沙: 湖南中医药大学, 2018.
10. 张琳琳, 王旭义, 陈晓东. Bernese髋臼周围截骨术术前规划的有限元分析方法研究. 生物医学工程学杂志, 2016, 33(3): 455-460.
11. 张英会, 刘辉航, 王德成. 弹簧手册. 北京: 机械工业出版社, 2017: 993-994.
12. Mooney M. A theory of large elastic deformation. J Appl Phys, 1940, 11(9): 582-592.
13. Rivlin R S. Large elastic deformations of isotropic materials. I. Fundamental concepts. Philos Trans R Soc A Math Phys Sci, 1948, 240(822): 459-490.
14. Treloar L R G. The elasticity of a network of long-chain molecules. I/II. Trans Faraday Soc, 1946, 42(4): 83-94.
15. Ogden R W. Large deformation isotropic elasticity–on the correlation of theory and experiment for incompressible rubberlike solids. Proc Math Phys Eng Sci, 1972, 326(1567): 565-584.
16. Yeoh O H. Some forms of the strain energy function for rubber. Rubber Chem Technol, 1993, 66(5): 754-771.
17. Limjeerajarus N, Fakkao M, Lampang S N, et al. Experimental data on mechanical behavior and numerical data on tensile stress distribution of a hyperelastic Polydimethysiloxane (PDMS) based membrane for cell culture. Data Brief, 2020, 30: 105476.
18. 刘鹏. 活体状态下人脸皮肤力学性能实验研究. 天津: 天津大学, 2017.
19. Hendriks F M, Brokken D, Oomens C W J, et al. The relative contributions of different skin layers to the mechanical behavior of human skin in vivo using suction experiments. Med Eng Phys, 2006, 28(3): 259-266.
20. 刘今越, 顾立振, 郭士杰, 等. 人体舒适度及翻身高度与各部位压力分布研究. 机械设计与制造, 2019(9): 30-34.
21. Payne T, Mitchell S, Bibb R, et al. The evaluation of new multi-material human soft tissue simulants for sports impact surrogates. J Mech Behav Biomed, 2015, 41: 336-356.
22. 刘鹏, 王世斌, 李林安, 等. 活体状态下人脸皮肤力学性能原位测量研究. 实验力学, 2017, 32(3): 295-304.
23. Allaire P E, Thacker J G, Edlich R F, et al. Finite deformation theory for in vivo human skin. J Bioeng, 1977, 1(3): 239-249.
24. Moes N C C M, Horvath I. Finite elements model of the human body: Geometry and non-linear material properties// Proceedings of the TMCE 2002. Wuhan: Huazhong University of Science and Technology, 2002: 477-493.
25. Bischoff J E, Arruda E M, Grosh K. Finite element modeling of human skin using an isotropic, nonlinear elastic constitutive model. J Biomech, 2000, 33(6): 645-652.
26. 孔祥清, 曲艳东, 章文姣, 等. 蚊子口针刺入皮肤的刺入力分析. 科技导报, 2013, 31(22): 60-63.
27. Metha A K, Wong F. Measurement of flammability and burn potential of fabrics. Cambridge: Fuels Research Laboratory, MIT, 1973.
28. 侯俊杰. 微针阵列刺入皮肤的理论与实验研究. 大连: 大连理工大学, 2013.
29. Gerling G J, Thomas G W. The effect of fingertip microstructures on tactile edge perception// First Joint Eurohaptics Conference and Symposium on Haptic Interfaces for Virtual Environment and Teleoperator Systems. World Haptics Conference. Pisa: IEEE, 2005: 63-72.
30. 董凤怡, 宋景艳, 赵晓梅, 等. 铺药隔姜灸治疗急性卡他性中耳炎25例. 中国针灸, 2017, 37(12): 1353-1354.
31. 范强芳, 王凤英, 李灿华, 等. 中药隔姜八髎灸治疗中重度原发性痛经临床研究. 针灸临床杂志, 2020, 36(6): 51-55.
32. 胡金明. 针织内衣接触舒适性研究. 上海: 东华大学, 2016.
33. 赵伟, 储满生, 汤雅婷, 等. 基于田口法的钒钛磁铁矿热压块抗压强度的优化. 东北大学学报(自然科学版), 2015, 36(10): 1441-1442.

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