Screening of place cell and analysis of its influencing factors for pigeons_Journal of Biomedical Engineering

Authors：

 LIU Xinyu ¹ , CUI Shuhua ² , YANG Chenguang ^1,3 , WANG Dongyun ¹ , LIU Kaige ^1,3 , QIN Yue ^1,3 ,  WEN Shengjun ³

1. School of Intelligent Manufacturing, Huanghuai University, Zhumadian, Henan 463000, P. R. China;
2. Department of Electrical Engineering, Kaifeng Technician College, Kaifeng, Henan 475004, P. R. China;
3. School of Electronic and Information Engineering, Zhongyuan University of Technology, Zhengzhou 450007, P. R. China;

Corresponding author：

LIU Xinyu, Email: liuxinyu@huanghuai.edu.cn; WEN Shengjun, Email: wsj@zut.edu.cn

Keywords：

Place cells; Place fields; Pigeons; Screening

DOI：

10.7507/1001-5515.202307023

Video：

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Abstract Full text Figures/Tables Video References Cited by

Place cell with location tuning characteristics play an important role in brain spatial cognition and navigation, but there is relatively little research on place cell screening and its influencing factors. Taking pigeons as model animals, the screening process of pigeon place cell was given by using the spike signal in pigeon hippocampus under free activity. The effects of grid number and filter kernel size on the place field of place cells during the screening process were analyzed. The results from the real and simulation data showed that the proposed place cell screening method presented in this study could effectively screen out place cell, and the research found that the size of place field was basically inversely proportional to the number of grids divided, and was basically proportional to the size of Gaussian filter kernel in the overall trend. This result will not only help to determine the appropriate parameters in the place cell screening process, but also promote the research on the neural mechanism of spatial cognition and navigation of birds such as pigeons.

Citation： LIU Xinyu, CUI Shuhua, YANG Chenguang, WANG Dongyun, LIU Kaige, QIN Yue, WEN Shengjun. Screening of place cell and analysis of its influencing factors for pigeons. Journal of Biomedical Engineering, 2024, 41(2): 335-341. doi: 10.7507/1001-5515.202307023 Copy

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13.	Jeffery K J. Symmetries and asymmetries in the neural encoding of 3D space. Philos Trans R Soc B Biol Sci, 2023, 378(1869): 20210452.

1. Tolman E C. Cognitive maps in rats and men. Psychol Rev, 1948, 55(4): 189-208.
2. O’Keefe J, Nadel L. The hippocampus as a cognitive map. Oxford: Oxford University Press, 1978: 1-21.
3. O’Keefe J, Dostrovsky J. The hippocampus as a spatial map: preliminary evidence from unit activity in the freely-moving rat. Brain Res, 1971, 34(1): 171-175.
4. Ulanovsky N, Moss C F. Hippocampal cellular and network activity in freely moving echolocating bats. Nat Neurosci, 2007, 10(2): 224-233.
5. Yartsev M M, Ulanovsky N. Representation of three-dimensional space in the hippocampus of flying bats. Science, 2013, 340(6130): 367-372.
6. 刘新玉, 万红, 陈雪美, 等. 鸽子海马区位置细胞及其空间响应特性分析. 中国科学: 生命科学, 2017, 47(3): 292-304.
7. Payne H L, Lynch G F, Aronov D. Neural representations of space in the hippocampus of a food-caching bird. Science, 2021, 373(6552): 343-348.
8. Liu X, Yang Y, Ping Y, et al. Avian nidopallium caudolaterale mediates decision-making during goal-directed navigation. J Integr Neurosci, 2021, 20(4): 945-954.
9. Liu X, Ping Y, Wang D, et al. Development of digital stereotaxic instrument for pigeons (Columba livia). J Bionic Eng, 2022, 19(4): 1003-1013.
10. Karten H J, Hodos W. Stereotaxic atlas of the brain of the pigeon (Columba livia). Baltimore: Johns Hopkins Press, 1967: 38-49.
11. Cajigas I, Malik W Q, Brown E N. nSTAT: Open-source neural spike train analysis toolbox for Matlab. J Neurosci Meth, 2012, 211(2): 245-264.
12. Mo F, Xu Z, Yang G, et al. Single-neuron detection of place cells remapping in short-term memory using motion microelectrode arrays. Biosens Bioelectron, 2022, 217: 114726.
13. Jeffery K J. Symmetries and asymmetries in the neural encoding of 3D space. Philos Trans R Soc B Biol Sci, 2023, 378(1869): 20210452.

Journal of Biomedical Engineering

Screening of place cell and analysis of its influencing factors for pigeons

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