Controllability and predictability of riboflavin-ultraviolet A collagen cross-linking: advances in experimental techniques and theoretical research_Journal of Biomedical Engineering

Authors：

LIU Xiaona ,  LI Xiaona , CHEN Weiyi

Collage of Artificial Intelligence, Taiyuan University of Technology, Taiyuan 030024, P. R. China;

Corresponding author：

Keywords：

Riboflavin-ultraviolet A collagen cross-linking; Depth-dependent cross-linking; Cross-linking effect; Controllability

DOI：

10.7507/1001-5515.202402017

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Riboflavin-ultraviolet A (UVA) collagen cross-linking has not only achieved good clinical efficacy in the treatment of corneal diseases such as dilatation keratopathy, bullae keratopathy, infectious keratopathy, and in the combined treatment of corneal refractive surgeries, but also its efficacy and safety in scleral collagen cross-linking have been initially confirmed. To better promote the application of cross-linking in the clinical treatment of corneal and scleral diseases, exploring controllability and predictability of the surgical efficacy are both important for evaluating the surgical efficacy and personalized precision treatment. In this paper, the progress on the cross-linking depth of riboflavin-UVA collagen cross-linking, and its relationship with the cross-linking effect will be reviewed. It will provide the reference for further application of this procedure in ophthalmology clinics.

Citation： LIU Xiaona, LI Xiaona, CHEN Weiyi. Controllability and predictability of riboflavin-ultraviolet A collagen cross-linking: advances in experimental techniques and theoretical research. Journal of Biomedical Engineering, 2025, 42(1): 212-218. doi: 10.7507/1001-5515.202402017 Copy

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Journal of Biomedical Engineering

Controllability and predictability of riboflavin-ultraviolet A collagen cross-linking: advances in experimental techniques and theoretical research

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