Etofenamate Gel and Foot Orthosis for Painful Hallux Valgus: A Randomized Controlled Clinical Trail_West China Medical Journal

Authors：

WANG Zhi , LI Zhong , XU Yangbo , CHEN Ge , ZHUO Naiqiang , LU Xiaobo.

Department of Bone and Joint Surgery, Affiliated Hospital of Luzhou Medical College, Luzhou, Sichuan 646000, P. R. China;

Corresponding author：

Keywords：

拇外翻; 托芬那酯凝胶; 足矫形器

DOI：

10.7507/1002-0179.20130117

Video：

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目的　了解依托芬那酯凝胶对有疼痛症状的轻中度拇外翻畸形的治疗效果。方法　对2010年3月－2011年7月门诊收治的轻中度拇外翻患者共65足，随机分成两组，治疗组采取托芬那酯凝胶局部应用和佩戴夜间支具，对照组佩戴夜间支具，局部应用安慰剂，治疗周期1个月。记录症状明显缓解时间，治疗前后对患者进行视觉模拟疼痛评分和美国骨科足踝分会跖趾及趾间关节评分，并测量拇外翻角和第一跖骨间角改变。结果　全部患者完成治疗，疼痛缓解时间治疗组为（3.28 ± 1.04）d，对照组（7.03 ± 2.15）d，差异有统计学意义（P＜0.05）,佩戴足矫形器治疗1个月，拇外翻角和第一跖骨间角改变无统计学差异（P＞0.05）。结论　局部应用依托芬那酯凝胶结合足矫形器治疗轻中度拇外翻能快速缓解疼痛症状，改善活动能力，延缓畸形加重，依托芬那酯凝胶局部给药患者能良好耐受，可避免口服非甾体抗炎药（NSAIDs）带来的副作用。

Citation： WANG Zhi,LI Zhong,XU Yangbo,CHEN Ge,ZHUO Naiqiang,LU Xiaobo.. Etofenamate Gel and Foot Orthosis for Painful Hallux Valgus: A Randomized Controlled Clinical Trail. West China Medical Journal, 2013, 28(3): 365-368. doi: 10.7507/1002-0179.20130117 Copy

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1. 　Wülker N, Mittag F. The treatment of hallux valgus[J]. Dtsch Arztebl Int，, 2012, 109(49): 857-868.
2. 　Bussewitz BW, Levar T, Hyer CF. Modern techniques in hallux abducto valgussurgery[J]. Clin Podiatr Med Surg, 2011, 28(2): 287-303.
3. 　Klemola T. Hallux valgus--several ways to treat[J]. Duodecim, 2011, 127(16): 1709-1718.
4. 　孙捷文, 陈丽平. 非甾体抗炎药的不良反应与合理使用[J]. 中国现代药物应用, 2009, 3(13)：99.
5. 　Mann RA, Coughlin MJ. Surgery of the foot and Ankle[M]. 7th ed. St. Louis, MO: Mosby, 1999: 150-175.
6. 　Hahn MP, Gerhardt N, Thordarson DB. Medial capsular interpositionalarthroplasty for severe hallux rigidus[J]. Foot Ankle Int, 2009, 30(6): 494-499.
7. 　Nix SE, Vicenzino BT, Collins NJ, et al. Characteristics of foot structure and footwear associated with hallux valgus: a systematic review[J]. Osteoarthritis Cartilage, 2012, 10(20): 1059-1074.
8. 　Lee KM, Ahn S, Chung CY, et al. Reliability and relationship of radiographic measurements in Hallux Valgus[J]. Clin Orthop Relat Res, 2012, 9(470): 2613-2621.
9. 　石凯, 刘志刚. “跖袖“的解剖学特点及临床意义[J]. 中国临床解剖学杂志, 2007, 25(3): 266-268.
10. 　Dereymaeker G, Mulier T, Girisch P. The first metatarsophalangeal jointmeniscus and its relation to hallux valgus deformity - an anatomical and clinical study[J]. Foot Ankle Surg, 2011, 17(4): 270-273.
11. 　Mirzashahi B, Ahmadifar M, Birjandi M, et al. Comparison of designed slippers splints with the splints available on the market in the treatment of hallux valgus[J]. Acta Med Iran, 2012, 50(2): 107-112.
12. 　Chlud K. Percutaneous therapy of painful arthritis[J]. Ther Umsch, 1991, 48(1): 42-45.
13. 　冷晓梅, 曾小峰, 黄慈波, 等. 依托芬那酯凝胶治疗关节痛的多中心随机开放对照研究[J]. 中国新药杂志, 2010, 19(14): 1241-1243.
14. 　Perera AM, Mason L, Stephens MM,et al. The pathogenesis of hallux valgus[J]. J Bone Joint Surg Am， 2011, 93(17): 1650-1661.
15. 　Assal M. Hallux valgus: which treatment[J]. Rev Med Suisse， 2005, 1(3): 258-263.

West China Medical Journal

Etofenamate Gel and Foot Orthosis for Painful Hallux Valgus: A Randomized Controlled Clinical Trail

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