Research on the Mental Health and Quality of Life of Patients with Impaired Glucose Tolerance_West China Medical Journal

Authors：

TANG Lei , DONG Zaiquan , JIANG Fugu , ZHANG Xu , FU Xiaoqian , YU Jianying ,  SUN Xueli.

Mental Health Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding author：

SUN Xueli., Email: tanglei0401@foxmail.com

Keywords：

糖耐量异常; 生活质量; 焦虑; 抑郁

DOI：

10.7507/1002-0179.20130172

Video：

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目的　探讨糖耐量异常患者的焦虑抑郁状况及其与生活质量的相关性，为糖尿病相关心理问题的早期识别与干预提供参考。方法　以2010年1月－2012年6月糖耐量异常患者145例为试验组，健康人群147例作为对照组，两组分别填写焦虑自评量表（SAS）和抑郁自评量表（SDS），试验组还需填写世界卫生组织生活质量测定量表简表（WHOQOL-BREF）并对其焦虑、抑郁得分与WHOQOL-BREF的各因子的相关性进行分析。结果　145例患者中有51例（35.2%）存在抑郁情绪，47例（32.4%）存在焦虑情绪，焦虑合并抑郁情绪者29例（20%）。糖耐量异常患者焦虑、抑郁评分明显高于对照组（P＜0.01），其生活质量多个领域评分低于对照组（P＜0.01），且生活质量与焦虑、抑郁情绪存在负相关（P＜0.05）。结论　糖耐量异常患者焦虑、抑郁情绪明显高于正常人群，其生活质量偏低，提示了对在该人群进行早期心理干预的必要性。

Citation： TANG Lei,DONG Zaiquan,JIANG Fugu,ZHANG Xu,FU Xiaoqian,YU Jianying,SUN Xueli.. Research on the Mental Health and Quality of Life of Patients with Impaired Glucose Tolerance. West China Medical Journal, 2013, 28(4): 537-539. doi: 10.7507/1002-0179.20130172 Copy

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1. 　Pouwer F, Kupper N, Adriaanse M. Does emotional stress cause type 2 diabetes mellitus? A review from the European depression in diabetes (EDID) research consortium[J]. Disc Med, 2010, 9(45): 112.
2. 　Rod NH, Grønbæk M, Schnohr P, et al. Perceived stress as a risk factor for changes in health behaviour and cardiac risk profile: a longitudinal study [J]. J Inter Med, 2009, 266(5): 467-475.
3. 　张明园. 精神科评定量表手册[M]. 2版.长沙:湖南科学技术出版社, 1998: 35-42.
4. 　Fisher L, Skaff MM, Mullan JT, et al. A longitudinal study of affective and anxiety disorders, depressive affect and diabetes distress in adults with type 2 diabetes[J]. Dia Med, 2008, 25(9): 1096-1101.
5. 　Anderson RJ, Freedland KE, Clouse RE, et al. The prevalence of comorbid depression in adults with diabetes a meta-analysis[J]. Dia Care, 2001, 24(6): 1069-1078.
6. 　Edelstein SL, Knowler WC, Bain RP, et al. Predictors of progression from impaired glucose tolerance to NIDDM: an analysis of six prospective studies[J]. Diabetes, 1997, 46(4): 701.
7. 　Tsai CH, Wu JS, Chang YF, et al. The relationship between psychiatric symptoms and glycemic status in a Chinese population[J]. J Psych Res, 2012, 46(7): 927-932.
8. 　Brown ES, Varghese FP, McEwen BS. Association of depression with medical illness: does cortisol play a role?[J]. Biol Psych, 2004, 55(1): 1-9.
9. 　Björntorp P. Heart and soul: stress and the metabolic syndrome[J]. Scand Cardio J, 2001, 35(3): 172-177.
10. 　Rosmond R. Stress induced disturbances of the HPA axis: a pathway to type 2 diabetes?[J]. International medical, 2003, 9(2): RA35.
11. 　Hotamisligil GS. Inflammation and metabolic disorders[J]. Nature, 2006, 444 (7121): 860-867.
12. 　徐红, 徐哲, 李玲. 糖尿病前期干预治疗在糖尿病防治中的作用[J]. 中国临床实用医学, 2010, 4(1): 225-226.
13. 　孙慧伶, 赵林双, 向光大, 等. 老年糖耐量低减患者心理状态调查[J]. 护理学杂志, 2006, 21(19): 61-62.
14. 　钟志廷, 赵玲双. 180例老年糖耐量异常患者心理健康状况调查[J]. 中国心理卫生杂志, 2005, 19(8): 542.

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Research on the Mental Health and Quality of Life of Patients with Impaired Glucose Tolerance

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