Clinicopathological Analysis on Sclerosing Epithelioid Fibrosarcoma_West China Medical Journal

Authors：

CHEN Shigao , MEI Aonan , XU Xiuying ,  YE LUuml

Department of Pathology, Gaoxin Daan Clinical laboratory, Chengdu, Sichuan 611731, P. R. China;

Corresponding author：

YE LUuml, Email: lululucsg@tom.com

Keywords：

软组织肿瘤; 纤维肉瘤; 硬化性上皮样纤维肉瘤; 免疫组织化学

DOI：

10.7507/1002-0179.20130379

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

目的　探讨硬化性上皮样纤维肉瘤（SEF）的临床病理学特征。方法　对2012年3月收治的l例SEF患者进行组织学观察、免疫组织化学检查并复习相关文献。结果　SEF主要以细胞质透亮的上皮样肿瘤细胞伴大量透明变性胶原纤维为特征，瘤细胞排列主要呈条索状、巢状。肿瘤细胞波形蛋白阳性表达，细胞角蛋白和平滑肌肌动蛋白阴性表达。结论　SEF是一种较为罕见的软组织肿瘤，应注意与一些具有上皮样形态和硬化性间质的肿瘤相鉴别。

Citation： CHEN Shigao,MEI Aonan,XU Xiuying,YE LUuml,.. Clinicopathological Analysis on Sclerosing Epithelioid Fibrosarcoma. West China Medical Journal, 2013, 28(8): 1215-1217. doi: 10.7507/1002-0179.20130379 Copy

1.	Meis-Kindblom JM, Kindblom LG, Enzinger FM. Sclerosing epithelioid fibrosarcoma: a variant of fibrosarcoma simulating carcinoma[J]. Am J Surg Pathol, 1995, 19(9): 979-993.
2.	Folk GS, Williams SB, Foss RB, et al. Oral and maxillofacial sclerosing epithelioid fibroscarcoma: report of five cases[J]. Head Neck Pathol, 2007, 1(1): 13-20.
3.	Ossendorf C, Studer GM, Bode B, et al. Sclerosing epithelioid fibrosarcoma: case presentation and a systematic review[J]. Clin Orthop Relat Res, 2008, 466(6): 1485-1491.
4.	Tomimaru Y, Nagano H, Marubashi S, et al. Sclerosing epithelioid fibrosarcoma of the liver infiltrating the inferior vena cava[J]. World J Gastroenterol, 2009, 15(33): 4204-4208.
5.	Frattini JC, Sosa JA, Carmack S, et al. Sclerosing epithelioid fibrosarcoma of the cecum: a radiation-associated tumor in a previously unreported site[J]. Arch Pathol Lab Med, 2007, 131(12): 1825-1828.
6.	Hanson IM, Pearson JM, Eyden BP, et al. Evidence of nerve sheath diferentiation and high grade morphology in sclerosing epithelioid fibrosarcoma[J]. J Clin Pathol, 2001, 54(9): 721-723.
7.	Rekhi B, Deshmukh M, Jambhekar NA. Low-grade fibromyxoid sarcoma: a clinicopathologic study of 18 cases, including histopathologic relationship with sclerosing epithelioid fibrosarcoma in a subset of cases[J]. Ann Diagn Pathol, 2011, 15(5): 303-311.
8.	Massier A, Scheithauer BW, Taylor HC, et al. Sclerosing epithelioid fibrosarcoma of the pituitary[J]. Endocr Pathol, 2007,18(4): 233-238.
9.	Jiao YF, Nakamura S, Sugai T, et al. Overexpression of MDM2 in a sclerosing epithelioid fibrosarcoma: genetic, immunohistochemical and ultrastructural study of a case[J]. Pathol Int, 2002, 52(2): 135-140.
10.	Ogose A, Kawashima H, Umezu H, et al. Schrosing epithelioid Fibrosarcoma with der(10)t(10；17)(p11；q11)[J]. Cancer Genet Cytogenet, 2004, 152(2): 136-140.
11.	Wang WL, Evans HL, Meis JM, et al. FUS rearrangements are rare in ‘pure’ sclerosing epithelioid fibrosarcoma[J]. Mod Pathol, 2012, 25(6): 846-853.
12.	Yoon N, Kwon JW, Seo SW, et al. Sclerosing epithelioid fibrosarcoma: cytogenetic analysis of FUS rearrangement[J]. Pathol Int, 2012, 62(1): 65-68.
13.	Elkins CT, Wakely PE Jr. Sclerosing epithelioid fibrosarcoma of the oral cavity[J]. Head Neck Pathol, 2011, 5(4): 428-431.
14.	Rekhi B, Folpe AL, Deshmukh M, et al. Sclerosing epithelioid fibrosarcoma - a report of two cases with cytogenetic analysis of FUS gene rearrangement by FISH technique[J]. Pathol Oncol Res, 2011, 17(1):145-148.

1. 　Meis-Kindblom JM, Kindblom LG, Enzinger FM. Sclerosing epithelioid fibrosarcoma: a variant of fibrosarcoma simulating carcinoma[J]. Am J Surg Pathol, 1995, 19(9): 979-993.
2. 　Folk GS, Williams SB, Foss RB, et al. Oral and maxillofacial sclerosing epithelioid fibroscarcoma: report of five cases[J]. Head Neck Pathol, 2007, 1(1): 13-20.
3. 　Ossendorf C, Studer GM, Bode B, et al. Sclerosing epithelioid fibrosarcoma: case presentation and a systematic review[J]. Clin Orthop Relat Res, 2008, 466(6): 1485-1491.
4. 　Tomimaru Y, Nagano H, Marubashi S, et al. Sclerosing epithelioid fibrosarcoma of the liver infiltrating the inferior vena cava[J]. World J Gastroenterol, 2009, 15(33): 4204-4208.
5. 　Frattini JC, Sosa JA, Carmack S, et al. Sclerosing epithelioid fibrosarcoma of the cecum: a radiation-associated tumor in a previously unreported site[J]. Arch Pathol Lab Med, 2007, 131(12): 1825-1828.
6. 　Hanson IM, Pearson JM, Eyden BP, et al. Evidence of nerve sheath diferentiation and high grade morphology in sclerosing epithelioid fibrosarcoma[J]. J Clin Pathol, 2001, 54(9): 721-723.
7. 　Rekhi B, Deshmukh M, Jambhekar NA. Low-grade fibromyxoid sarcoma: a clinicopathologic study of 18 cases, including histopathologic relationship with sclerosing epithelioid fibrosarcoma in a subset of cases[J]. Ann Diagn Pathol, 2011, 15(5): 303-311.
8. 　Massier A, Scheithauer BW, Taylor HC, et al. Sclerosing epithelioid fibrosarcoma of the pituitary[J]. Endocr Pathol, 2007,18(4): 233-238.
9. 　Jiao YF, Nakamura S, Sugai T, et al. Overexpression of MDM2 in a sclerosing epithelioid fibrosarcoma: genetic, immunohistochemical and ultrastructural study of a case[J]. Pathol Int, 2002, 52(2): 135-140.
10. 　Ogose A, Kawashima H, Umezu H, et al. Schrosing epithelioid Fibrosarcoma with der(10)t(10；17)(p11；q11)[J]. Cancer Genet Cytogenet, 2004, 152(2): 136-140.
11. 　Wang WL, Evans HL, Meis JM, et al. FUS rearrangements are rare in ‘pure’ sclerosing epithelioid fibrosarcoma[J]. Mod Pathol, 2012, 25(6): 846-853.
12. 　Yoon N, Kwon JW, Seo SW, et al. Sclerosing epithelioid fibrosarcoma: cytogenetic analysis of FUS rearrangement[J]. Pathol Int, 2012, 62(1): 65-68.
13. 　Elkins CT, Wakely PE Jr. Sclerosing epithelioid fibrosarcoma of the oral cavity[J]. Head Neck Pathol, 2011, 5(4): 428-431.
14. 　Rekhi B, Folpe AL, Deshmukh M, et al. Sclerosing epithelioid fibrosarcoma - a report of two cases with cytogenetic analysis of FUS gene rearrangement by FISH technique[J]. Pathol Oncol Res, 2011, 17(1):145-148.

West China Medical Journal

Clinicopathological Analysis on Sclerosing Epithelioid Fibrosarcoma

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content