• Department of Pharmacy, General Hospital of Chengdu Military Region, Chengdu, Sichuan 610083, P. R. China;
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目的  观察秦绵祛风胶囊对鹌鹑高尿酸血症的影响。 方法   通过喂饲用酵母配制的造模饲料造成鹌鹑高尿酸血症模型,设秦绵祛风胶囊高、中、低3个剂量组并以苯溴马隆为阳性对照,在造模的同时连续灌胃药35 d,检测血中黄嘌呤氧化酶、尿酸、血尿素氮和三酰甘油及粪便中尿酸含量。 结果   模型动物血清中黄嘌呤氧化酶、尿酸和三酰甘油水平及粪便中尿酸含量较正常对照组明显升高。秦绵祛风胶囊各剂量组均可显著降低鹌鹑血清中的尿酸和三酰甘油水平,同时升高粪便中尿酸含量,对血清中黄嘌呤氧化酶活性影响不大。 结论  秦绵祛风胶囊具有降脂降尿酸的功能,其机制可能是通过提高动物排泄尿酸的能力,从而降低血中尿酸的含量。

Citation: WANG Shihua,LIANG Rongmei,TAN Yonghong,JIANG Yan.. Effect of Qin-mian Dispelling Wind Capsule on High Uric Acid Hematic Disease Model of Quail. West China Medical Journal, 2013, 28(11): 1686-1688. doi: 10.7507/1002-0179.20130532 Copy

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