Objective To observe the therapeutic effect of electro-acupuncture combined with oral glucosamine hydrochloride capsules in the treatment of knee osteoarthritis, and compare it with the curative effect of the two methods separately. Methods A total of 168 patients with knee osteoarthritis treated from March 2006 to December 2012 were randomly divided into 3 groups. Electro-acupuncture combined with oral glucosamine hydrochloride capsules were given to the 58 patients in the treatment group, single acupuncture treatment was given to the 57 patients in control group A, and simple oral glucosamine hydrochloride capsules were given to the 53 patients in control group B. The treatment lasted for 6 weeks. Assessment of knee osteoarthritis by Lequesne international standard index number and the total efficiency was carried out before treatment and 3 weeks, 6 weeks and 6 months after treatment, respectively. Results The total effective rate of the treatment group was 91.38%, of control group A was 68.42%, and of control group B was 79.25%. There was a significant difference between the treatment group and control group A, and between the treatment group and control group B (P<0.05). No blood, liver or kidney damage or gastrointestinal adverse reaction occurred among patients in all the three groups. Conclusion The efficacy of electro-acupuncture plus oral glucosamine hydrochloride capsules is better than simple acupuncture and simple oral glucosamine hydrochloride capsules treatment.

Citation： HUANGJian, YANGLi-wei. Clinical Observation of Electro-acupuncture Combined with Oral Glucosamine Hydrochloride Capsules for the Treatment of Knee Osteoarthritis. West China Medical Journal, 2014, 29(1): 30-33. doi: 10.7507/1002-0179.20140009 Copy