Objective To investigate the ultrasonic changes of liver during various immune periods with different number of CD4⁺ T lymphocytes in HIV/AIDS patients with chronic viral hepatitis. Methods The clinical data of 100 patients with chronic viral hepatitis diagnosed between January 2010 and December 2012 were selected. Among them, 50 simple chronic viral hepatitis patients were designated as the control group, and the other 50 HIV/AIDS patients with chronic viral hepatitis were regarded as the experimental group. Ultrasonographic observation was applied on patients of the experimental group according to different immune period based on the number of CD4⁺ T lymphocytes. Indexes observed included liver size, the edge of liver, capsule of liver and hepatic parenchymal echo. The cross-check analysis was employed between observed results and clinical laboratory results. Results Abnormal changes of the experimental group were shown on the ultrasound observation of liver in different CD4⁺ T lymphocyte count immune periods, including enlargement of the liver, slightly blunt liver margin, slightly thick capsule, dense and uniform, slightly rough and not so uniform, or rough and not uniform hepatic parenchymal echo. There was no significant difference in ultrasonic changes of liver between the two groups when the CD4⁺ T cell number was over 300/mm³. However, the difference was significant when the CD4⁺ T cell number was below 100/mm³. Conclusion Liver abnormalities become more obvious as CD4⁺ T cell count decreases in HIV/AIDS patients with chronic viral hepatitis. Comprehensive considerations of various liver ultrasound indicators are helpful in clinical evaluation of HIV/AIDS patients with chronic viral hepatitis.

Citation： CAOFen, YEQing. Study on the Correlation between Ultrasonographic Features of HIV/AIDS in Patients with Chronic Viral Hepatitis and CD4⁺ T Lymphocyte Number. West China Medical Journal, 2014, 29(1): 80-82. doi: 10.7507/1002-0179.20140022 Copy