慢性前列腺炎循证医学治疗概况_West China Medical Journal

Authors：

 王亚波 , 陈德强

成都市龙泉驿区第一人民医院泌尿外科（成都，610100）;

Corresponding author：

Keywords：

慢性前列腺炎; 循证医学; 治疗; 综述

DOI：

10.7507/1002-0179.20140054

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慢性前列腺炎（CP）是发病率非常高、临床症状复杂、治疗棘手的成年男性常见疾病之一，由于其发病机制、病理生理学改变还不十分清楚，目前治疗尚无统一方案。现按美国国立卫生研究院分类的Ⅱ型及Ⅲ型CP标准，就循证治疗现状作综述评价并就目前状况提出问题与展望。

Citation： 王亚波, 陈德强. 慢性前列腺炎循证医学治疗概况. West China Medical Journal, 2014, 29(1): 183-186. doi: 10.7507/1002-0179.20140054 Copy

1.	Nickel JC, Downey J, Hunter D, et al. Prevalence of prostatitis-like symptoms in a population based study using the National Institutes of Health chronic prostatitis symptom index[J]. J Urol, 2001, 165(3):842-845.
2.	Litwin MS, Mcnaughton-Collins M, Fowler F, et al. The National Institutes of Health chronic prostatitis symptom index:development and validation of a new outcome measure[J]. J Urol, 1999, 162(2):369-375.
3.	Nickel JC, Downey J, Clark J, et al. Levofloxacin for chronic prostatitis/chronic pelvic pain syndrome in men:a randomized placebo-controlled multicenter trial[J]. Urology, 2003, 62(4):614-617.
4.	杨明根, 赵晓昆, 候轶. 慢性前列腺炎/慢性盆底疼痛综合征(CP/CPPS)治疗有效性和安全性的系统评价(Meta分析)[J]. 中国男科学杂志, 2008, 22(4):20-26.
5.	Nickel JC, Narayan P, McKay J, et al. Treatment of chronic prostatitis/chronic pelvic pain syndrome with tamsulosin:a randomized double blind trial[J]. J Urol, 2004, 171(4):1594-1597.
6.	Nickel JC. Role of alpha1-blockers in chronic prostatitis syndromes[J]. BJU Int, 2008, 101(3):11-16.
7.	埃杜, 莫曾南. 特拉唑嗪治疗慢性前列腺炎/慢性盆腔疼痛综合征的系统评价[J].广西医学, 2007, 29(6):789-792.
8.	Yang G, Wei Q, Li H, et al. The effect of alpha-adrenergic antagonists in chronic prostatitis/chronic pelvic pain syndrome:a meta-analysis of randomized controlled trials[J]. J Androl, 2006, 27(6):847-852.
9.	曾晓勇,叶章群,杨为民, 等. 塞来昔布治疗ⅢA型前列腺炎的临床评估[J]. 中华男科学杂志, 2004, 10(4):278-281.
10.	Nickel JC, Pontari M, Moon T, et al. A randomized, placebo controlled, multicenter study to evaluate the safety and efficacy of rofecoxib in the treatment of chronic nonbacterial prostatitis[J]. J Urol, 2003, 169(4):1401-1405.
11.	Elist J. Effects of pollen extract preparation Prostat/Poltit on lower urinary tract symptoms in patients with chronic nonbacterial prostatitis/chronic pelvic pain syndrome:a randomized, double-blind, placebo-controlled study[J]. Urology, 2006, 67(1):60-63.
12.	Shoskes DA, Zeitlin SI, Shahed A, et al. Quercetin in men with categoryⅢ chronic prostatitis:a preliminary prospective, double-blind, placebo-controlled trial[J]. J Urol, 1996, 155(3):965-968.
13.	史立新, 李钢, 杨勇, 等. 舍曲林合并米诺环素治疗慢性前列腺炎伴抑郁状态[J]. 中国心理卫生杂志, 2006, 20(7):476-478.
14.	卜红民, 闰拥军, 王连渠, 等. 抗抑郁药物治疗慢性前列腺炎60例[J].中国临床康复杂志, 2003, 7(29):40-47.
15.	Ziaee AM, Akhavizadegan H, Karbakhsh M, et al. Effect of allopurinol in chronic nonbacterial prostatitis:a double blind randomized clinical trial[J]. International Braz J Urol, 2006, 32(2):181-186.
16.	Lee SW, Liong ML, Yuen KH, et al. Acupuncture versus sham acupuncture for chronic prostatitis/chronic pelvic pain[J]. Am J Med, 2008, 121(1):79.e1-79.e7.
17.	Han P, Wei Q, Shi M, et al. Prostant in the treatment of chronic prostatitis:a meta-analysis[J]. Asian J Androl, 2004, 6(4):385.
18.	杨明根,赵晓昆,王新君.中国慢性前列腺炎治疗的有效性和安全性系统评价[J].中国循证医学杂志, 2007, 7(10):737-742.
19.	Chen JX, Hu LS. Traditional chinese medicine for the treatment of chronic prostatitis in China:a systematic review and meta-analysis[J]. J Altern Complement Med, 2006, 12(8):763-769.
20.	Ateya A, Fayez A, Hani R, et al. Evaluation of prostatic massage in treatment of chronic prostatitis[J]. Urology, 2006, 67(4):674-678.
21.	刘云飞, 陈实新, 邢金春, 等. 生物反馈联合药物治疗慢性前列腺炎的临床研究[J].中国医师进修杂志, 2007, 30(8):19-21.
22.	陈修德, 郑宝钟, 金讯波, 等. 慢性前列腺炎患者的心理障碍及治疗[J]. 中华男科学杂志, 2004, 10(2):113-114.
23.	薛银萍, 张士斌, 高彤, 等. 温针灸为主治疗慢性前列腺炎疗效观察[J]. 中国针灸, 2006, 26(5):335-336.
24.	Zeng XY, Liang C, and Ye ZQ. Extracorporeal shock wave treatment for non-inflammatory chronic pelvic pain syndrome:a prospective, randomized and sham-controlled study[J]. Chin Med J, 2012, 125(1):114-118.
25.	郭东发, 张辉泽, 王怀鹏. 高气固肾胶囊联合左氧氟沙星治疗ⅢA型前列腺炎的临床观察[J]. 中华男科学杂志, 2008, 14(1):88-90.
26.	Jeong CW, Lim DJ, Son H, et al. Treatment for chronic prostatitis/chronic pelvic pain syndrome:levofloxacin, doxazosin and their combination[J]. Urol Int, 2008, 80(2):157-161.
27.	Tuğcu V, Taşçi AI, Fazlioğlu A, et al. A placebo-controlled comparison of the efficiency of triple- and monotherapy in category Ⅲ B chronic pelvic pain syndrome (CPPS)[J]. Eur Urol, 2007, 51(4):1113-1117.
28.	Alexander RB, Propert KJ, Schaeffer AJ, et al. Ciprofloxacin or tamsulosin in men with chronic prostatitis/chronic pelvic pain syndrome:a randomized, double-blind trial[J]. Ann Intern Med, 2004, 141(8):581-589.

1. Nickel JC, Downey J, Hunter D, et al. Prevalence of prostatitis-like symptoms in a population based study using the National Institutes of Health chronic prostatitis symptom index[J]. J Urol, 2001, 165(3):842-845.
2. Litwin MS, Mcnaughton-Collins M, Fowler F, et al. The National Institutes of Health chronic prostatitis symptom index:development and validation of a new outcome measure[J]. J Urol, 1999, 162(2):369-375.
3. Nickel JC, Downey J, Clark J, et al. Levofloxacin for chronic prostatitis/chronic pelvic pain syndrome in men:a randomized placebo-controlled multicenter trial[J]. Urology, 2003, 62(4):614-617.
4. 杨明根, 赵晓昆, 候轶. 慢性前列腺炎/慢性盆底疼痛综合征(CP/CPPS)治疗有效性和安全性的系统评价(Meta分析)[J]. 中国男科学杂志, 2008, 22(4):20-26.
5. Nickel JC, Narayan P, McKay J, et al. Treatment of chronic prostatitis/chronic pelvic pain syndrome with tamsulosin:a randomized double blind trial[J]. J Urol, 2004, 171(4):1594-1597.
6. Nickel JC. Role of alpha1-blockers in chronic prostatitis syndromes[J]. BJU Int, 2008, 101(3):11-16.
7. 埃杜, 莫曾南. 特拉唑嗪治疗慢性前列腺炎/慢性盆腔疼痛综合征的系统评价[J].广西医学, 2007, 29(6):789-792.
8. Yang G, Wei Q, Li H, et al. The effect of alpha-adrenergic antagonists in chronic prostatitis/chronic pelvic pain syndrome:a meta-analysis of randomized controlled trials[J]. J Androl, 2006, 27(6):847-852.
9. 曾晓勇,叶章群,杨为民, 等. 塞来昔布治疗ⅢA型前列腺炎的临床评估[J]. 中华男科学杂志, 2004, 10(4):278-281.
10. Nickel JC, Pontari M, Moon T, et al. A randomized, placebo controlled, multicenter study to evaluate the safety and efficacy of rofecoxib in the treatment of chronic nonbacterial prostatitis[J]. J Urol, 2003, 169(4):1401-1405.
11. Elist J. Effects of pollen extract preparation Prostat/Poltit on lower urinary tract symptoms in patients with chronic nonbacterial prostatitis/chronic pelvic pain syndrome:a randomized, double-blind, placebo-controlled study[J]. Urology, 2006, 67(1):60-63.
12. Shoskes DA, Zeitlin SI, Shahed A, et al. Quercetin in men with categoryⅢ chronic prostatitis:a preliminary prospective, double-blind, placebo-controlled trial[J]. J Urol, 1996, 155(3):965-968.
13. 史立新, 李钢, 杨勇, 等. 舍曲林合并米诺环素治疗慢性前列腺炎伴抑郁状态[J]. 中国心理卫生杂志, 2006, 20(7):476-478.
14. 卜红民, 闰拥军, 王连渠, 等. 抗抑郁药物治疗慢性前列腺炎60例[J].中国临床康复杂志, 2003, 7(29):40-47.
15. Ziaee AM, Akhavizadegan H, Karbakhsh M, et al. Effect of allopurinol in chronic nonbacterial prostatitis:a double blind randomized clinical trial[J]. International Braz J Urol, 2006, 32(2):181-186.
16. Lee SW, Liong ML, Yuen KH, et al. Acupuncture versus sham acupuncture for chronic prostatitis/chronic pelvic pain[J]. Am J Med, 2008, 121(1):79.e1-79.e7.
17. Han P, Wei Q, Shi M, et al. Prostant in the treatment of chronic prostatitis:a meta-analysis[J]. Asian J Androl, 2004, 6(4):385.
18. 杨明根,赵晓昆,王新君.中国慢性前列腺炎治疗的有效性和安全性系统评价[J].中国循证医学杂志, 2007, 7(10):737-742.
19. Chen JX, Hu LS. Traditional chinese medicine for the treatment of chronic prostatitis in China:a systematic review and meta-analysis[J]. J Altern Complement Med, 2006, 12(8):763-769.
20. Ateya A, Fayez A, Hani R, et al. Evaluation of prostatic massage in treatment of chronic prostatitis[J]. Urology, 2006, 67(4):674-678.
21. 刘云飞, 陈实新, 邢金春, 等. 生物反馈联合药物治疗慢性前列腺炎的临床研究[J].中国医师进修杂志, 2007, 30(8):19-21.
22. 陈修德, 郑宝钟, 金讯波, 等. 慢性前列腺炎患者的心理障碍及治疗[J]. 中华男科学杂志, 2004, 10(2):113-114.
23. 薛银萍, 张士斌, 高彤, 等. 温针灸为主治疗慢性前列腺炎疗效观察[J]. 中国针灸, 2006, 26(5):335-336.
24. Zeng XY, Liang C, and Ye ZQ. Extracorporeal shock wave treatment for non-inflammatory chronic pelvic pain syndrome:a prospective, randomized and sham-controlled study[J]. Chin Med J, 2012, 125(1):114-118.
25. 郭东发, 张辉泽, 王怀鹏. 高气固肾胶囊联合左氧氟沙星治疗ⅢA型前列腺炎的临床观察[J]. 中华男科学杂志, 2008, 14(1):88-90.
26. Jeong CW, Lim DJ, Son H, et al. Treatment for chronic prostatitis/chronic pelvic pain syndrome:levofloxacin, doxazosin and their combination[J]. Urol Int, 2008, 80(2):157-161.
27. Tuğcu V, Taşçi AI, Fazlioğlu A, et al. A placebo-controlled comparison of the efficiency of triple- and monotherapy in category Ⅲ B chronic pelvic pain syndrome (CPPS)[J]. Eur Urol, 2007, 51(4):1113-1117.
28. Alexander RB, Propert KJ, Schaeffer AJ, et al. Ciprofloxacin or tamsulosin in men with chronic prostatitis/chronic pelvic pain syndrome:a randomized, double-blind trial[J]. Ann Intern Med, 2004, 141(8):581-589.

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