• 1. Department of Respiratory Medicine, the First People's Hospital of Longquanyi District of Chengdu City, Chengdu, Sichuan 610100, P. R. China;
  • 2. Department of Nephrology, People's Hospital, Guangzhou, Guangdong 510080, P. R. China;
  • 3. Department of Respiratory Medicine, People's Hospital, Guangzhou, Guangdong 510080, P. R. China;
LIANGXin-ling, Email: xinlingliang@yahoo.com
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Objective To investigate the role on adverse prognosis and risk factors of acute kidney injury (AKI) in hospitalized patients with chronic obstructive pulmonary disease (COPD). Methods Clinical data from hospitalized patients with COPD between January 2009 and June 2012 were studied retrospectively.AKI was diagnosed and classified by AKIN criterion. Results Three hundred and sixty-nine patients were enrolled,among whom 69(18.6%) were complicated with AKI.The patients with AKI were older,and had higher levels of hemoglobin,hematocrit value and sodium concentration,and higher rates of comorbidities of diabetes mellitus,proteinuria and shock,compared with the controls.Those with AKI had a 24.1% increased risk for ventilator,121.5% for intensive care,and 89.8% for death.And a higher AKI grade was related to a worse prognosis.The increased risk of AKI was 142.1% for every 5-year increase of age,155.7% for every 0.1 increase of hematocrit value,70.5% for every 0.1 increase of sodium concentration,and 49.1%,89.2%,148.2% and 685.7% for being complicated with proteinuria,coronary artery disease,diabetes mellitus and shock. Conclusion AKI is associated with adverse prognosis in hospitalized patients with COPD.Age,proteinuria,increased levels of hematocrit value and sodium concentration,and comorbidities of coronary artery disease,diabetes mellitus and shock are independent risk factors for AKI

Citation: LIUAn-li, LIUYing, LIZhi-lian, CHENZi-xing, YEGuang-lin, TAOYi-ming, CHENYuan-han, LIANGXin-ling. Clinical Characteristics of Acute Kidney Injury in Hospitalized Patients with Chronic Obstructive Pulmonary Disease. West China Medical Journal, 2014, 29(2): 236-238. doi: 10.7507/1002-0179.20140073 Copy

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