The Significance of Endoscopic Punctiform Erosion around Appendiceal Orifice with Diffused Inflammation in Left Semicolon in the Diagnosis of Ulcerative Colitis_West China Medical Journal

Authors：

 DENGPeng , GANTao ,  WUJun-chao

Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding author：

WUJun-chao, Email: wujunchao615@qq.com

Keywords：

Ulcerative colitis; Skip lesion; Appendiceal orifice

DOI：

10.7507/1002-0179.20140077

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To investigate the significance of endoscopic punctiform erosion around appendiceal orifice with diffused inflammation in left semicolon in the diagnosis of ulcerative colitis. Methods Twenty-nine patients with endoscopic punctiform erosion around appendiceal orifice with diffused inflammation in left semicolon treated in West China Hospital from January 2007 to November 2012 were included in our study.Patients with either edema,ulcer,polyps around the appendiceal orifice,inflammation in the ascending colon or transverse colon,or segmental inflammation in left semicolon were excluded.The endoscopic characteristic changes and the final diagnosis were compared by means of the pathological biopsy. Results Of the total 29 patients with characteristic changes under the endoscope,26 patients were eventually diagnosed to have left-sided ulcerative colitis,one was identified to be with Cronh's disease,and the remaining two patients could not be classified. Conclusion Our findings suggest that the characteristic changes under the endoscope may help the diagnosis of ulcerative colitis.

Citation： DENGPeng, GANTao, WUJun-chao. The Significance of Endoscopic Punctiform Erosion around Appendiceal Orifice with Diffused Inflammation in Left Semicolon in the Diagnosis of Ulcerative Colitis. West China Medical Journal, 2014, 29(2): 249-251. doi: 10.7507/1002-0179.20140077 Copy

1.	Cohen T,Pfeffer RB,Valensi Q. "Ulcerative appendicitis" occurring as a skip lesion in chronic ulcerative colitis:report of a case[J].Am J Gastroenterol,1974,62(2):151-155.
2.	欧阳钦.溃疡性结肠炎临床诊断指南[J].临床消化病杂志,2007,19(1):4-6.
3.	中华医学会消化病学分会炎症性肠病协作组.对我国炎症性肠病诊断治疗规范的共识意见(2007年,济南)[J].中华消化杂志,2007,27(8):545-550.
4.	Massac E Jr,Rawlings L,Kurtz L.Segmental ulcerative colitis:a case report and review of the literature[J].J Natl Med Assoc,1982,74(3):286-288.
5.	Rubin DT,Rothe JA.The peri-appendiceal red patch in ulcerative colitis:review of the University of Chicago experience[J].Dig Dis Sci,2010,55(12):3495-3501.
6.	Naves JE,Lorenzo-Zúñiga V,Marín L,et al.Long-term outcome of patients with distal ulcerative colitis and inflammation of the appendiceal orifice[J].J Gastrointestin Liver Dis,2011,20(4):355-358.
7.	Perry WB,Opelka FG,Smith D,et al.Discontinuous appendiceal involvement in ulcerative colitis:pathology and clinical correlation[J].J Gastrointest Surg,1999,3(2):141-144.
8.	Hokama A,Ihama Y,Chinen H,et al.Appendiceal orifice inflammation in ulcerative colitis[J].Dig Dis Sci,2010,55(4):1189.
9.	Matsumoto T,Nakamura S,Shimizu M,et al.Significance of appendiceal involvement in patients with ulcerative colitis[J].Gastrointest Endosc,2002,55(2):180-185.
10.	Radford-Smith GL,Edwards JE,Purdie DM,et al.Protective role of appendiectomy on onset and severity of ulcerative colitis and Crohn's disease[J].Gut,2002,51(6):808-813.
11.	Cosnes J,Carbonnel F,Beaugerie L,et al.Effect of appendicectomy on course of ulcerative colitis[J].Gut,2002,51(6):803-807.
12.	Mizoguchi A,Mizoguchi E,Chiba C,et al.Role of appendix in the development of imflammatory bowel diease in the TCR-a mutant mice[J].J Exp Med,1996,184(2):707-715.
13.	Yamagishi N,Iizuka B,Nakamura T,et al.Clinical and colonoscopic investigation of skipped periappendiceal lesions in ulcerative colitis[J].Scand J Gastroenterol,2002,37(2):177-182.
14.	Lucci E,Lattuneddu A,Valpiani D,et al.Skip lesion of the cecum associated with proctitis:an atypical case of ulcerative colitis[J].Dig Liver Dis,2004,36(12):847-851.
15.	Chiba M,Yamano H,Fujiwara K,et al.Lymph folliculitis in ulcerative colitis[J].Scand J Gastroenterol,2001,36(3):332-336.
16.	D'Haens G,Geboes K,Peeters M,et al.Patchy cecal inflammation associated with distal ulcerative colitis:a prospective endoscopic study[J].Am J Gastroenterol,1997,92(8):1275-1279.
17.	兰永臻,王朔,刘晓慧,等.阑尾口周围黏膜非连续性病变对非全结肠型溃疡性结肠炎诊断价值的探讨[J].临床荟萃,2008,23(13):943-944.
18.	Ladefoged K,Munck LK,Jorgensen F,et al.Skip inflammation of the appendiceal orifice:a prospective endoscopic study[J].Scand J Gastroenterol,2005,40(10):1192-1196.

1. Cohen T,Pfeffer RB,Valensi Q. "Ulcerative appendicitis" occurring as a skip lesion in chronic ulcerative colitis:report of a case[J].Am J Gastroenterol,1974,62(2):151-155.
2. 欧阳钦.溃疡性结肠炎临床诊断指南[J].临床消化病杂志,2007,19(1):4-6.
3. 中华医学会消化病学分会炎症性肠病协作组.对我国炎症性肠病诊断治疗规范的共识意见(2007年,济南)[J].中华消化杂志,2007,27(8):545-550.
4. Massac E Jr,Rawlings L,Kurtz L.Segmental ulcerative colitis:a case report and review of the literature[J].J Natl Med Assoc,1982,74(3):286-288.
5. Rubin DT,Rothe JA.The peri-appendiceal red patch in ulcerative colitis:review of the University of Chicago experience[J].Dig Dis Sci,2010,55(12):3495-3501.
6. Naves JE,Lorenzo-Zúñiga V,Marín L,et al.Long-term outcome of patients with distal ulcerative colitis and inflammation of the appendiceal orifice[J].J Gastrointestin Liver Dis,2011,20(4):355-358.
7. Perry WB,Opelka FG,Smith D,et al.Discontinuous appendiceal involvement in ulcerative colitis:pathology and clinical correlation[J].J Gastrointest Surg,1999,3(2):141-144.
8. Hokama A,Ihama Y,Chinen H,et al.Appendiceal orifice inflammation in ulcerative colitis[J].Dig Dis Sci,2010,55(4):1189.
9. Matsumoto T,Nakamura S,Shimizu M,et al.Significance of appendiceal involvement in patients with ulcerative colitis[J].Gastrointest Endosc,2002,55(2):180-185.
10. Radford-Smith GL,Edwards JE,Purdie DM,et al.Protective role of appendiectomy on onset and severity of ulcerative colitis and Crohn's disease[J].Gut,2002,51(6):808-813.
11. Cosnes J,Carbonnel F,Beaugerie L,et al.Effect of appendicectomy on course of ulcerative colitis[J].Gut,2002,51(6):803-807.
12. Mizoguchi A,Mizoguchi E,Chiba C,et al.Role of appendix in the development of imflammatory bowel diease in the TCR-a mutant mice[J].J Exp Med,1996,184(2):707-715.
13. Yamagishi N,Iizuka B,Nakamura T,et al.Clinical and colonoscopic investigation of skipped periappendiceal lesions in ulcerative colitis[J].Scand J Gastroenterol,2002,37(2):177-182.
14. Lucci E,Lattuneddu A,Valpiani D,et al.Skip lesion of the cecum associated with proctitis:an atypical case of ulcerative colitis[J].Dig Liver Dis,2004,36(12):847-851.
15. Chiba M,Yamano H,Fujiwara K,et al.Lymph folliculitis in ulcerative colitis[J].Scand J Gastroenterol,2001,36(3):332-336.
16. D'Haens G,Geboes K,Peeters M,et al.Patchy cecal inflammation associated with distal ulcerative colitis:a prospective endoscopic study[J].Am J Gastroenterol,1997,92(8):1275-1279.
17. 兰永臻,王朔,刘晓慧,等.阑尾口周围黏膜非连续性病变对非全结肠型溃疡性结肠炎诊断价值的探讨[J].临床荟萃,2008,23(13):943-944.
18. Ladefoged K,Munck LK,Jorgensen F,et al.Skip inflammation of the appendiceal orifice:a prospective endoscopic study[J].Scand J Gastroenterol,2005,40(10):1192-1196.

West China Medical Journal

The Significance of Endoscopic Punctiform Erosion around Appendiceal Orifice with Diffused Inflammation in Left Semicolon in the Diagnosis of Ulcerative Colitis

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content