成都地区常见过敏原致敏情况研究_West China Medical Journal

Authors：

 周培媚 , 路永红 , 刘艳 , 黄晶玉 , 方建蓉 , 顾兰秋 , 刘兰

成都市第二人民医院皮肤科（成都，610017）;

Corresponding author：

Keywords：

变应原; 皮肤点刺试验; 皮肤病; 过敏性

DOI：

10.7507/1002-0179.20140093

Video：

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目的了解成都地区常见过敏性皮肤病变应原分布情况。方法对2012年9月－11月收治的836例过敏性皮肤病患者进行皮肤点刺试验。结果在所检阳性变应原中，吸入性变应原数量居多，其中尘螨最多，90%以上患者存在2种或2种以上变应原检测阳性现象。结论尘螨变应原是成都地区过敏性皮肤病的重要致敏原。

Citation： 周培媚, 路永红, 刘艳, 黄晶玉, 方建蓉, 顾兰秋, 刘兰. 成都地区常见过敏原致敏情况研究. West China Medical Journal, 2014, 29(2): 305-306. doi: 10.7507/1002-0179.20140093 Copy

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1. Krouse JH,Stachler RJ,Shah A.Current in vivo and in vivo screens for inhalant allergy[J].Otolaryngol Clin North Am,2003,36(5):855-868.
2. King MJ,Lockey RF.Allergen prick-puncture skin testing in the elderly[J].Drugs Aging,2003,20(14):1011-1017.
3. 李彩虹,张振国,苏宗义.两种不同方法检测常见过敏原的对比分析[J].大连医科大学学报,2009,31(3):346-347,363.
4. 李大宁,刘进芬,金文,等.变应原皮肤点刺试验在7种过敏性皮肤病中的应用[J].临床皮肤科杂志,2003,32(11):653-654.
5. 史天威,张敏,陈燕辉,等.荨麻疹患者390例变应原检测分析[J].临床皮肤科杂志,2012,41(8):468-470.
6. 冯文莉,杨静,张荣丽,等.慢性荨麻疹湿疹患者皮肤点刺试验变应原检测结果分析[J].山西医药杂志,2006,35(10):942-943.
7. Wong CK,Li ML,Wang CB,et al.House dust mite allergen Der p 1 elevates the release of inflammatory cytokines and expression of adhesion molecules in co-culture of human eosinophils and bronchial epithelial cells[J].Int Immunol,2006,18(8):1327-1335.
8. Ghaemmaghami AM,Shakib F.Human T cells that have been conditioned by the proteolytic activity of the major dust mite allergen Der p 1 trigger enhanced immunoglobulin E synthesis by B cells[J].Clin Exp Allergy,2002,32(5):728-732.
9. Ghaemmaghami AM,Robins A,Gough L,et al.Human T cell subset commitment determined by the intrinsic property of antigen:the proteolytic activity of the major mite allergen Der p 1 conditions T cells to produce more IL-4 and less IFN-gamma[J].Eur J Immunol,2001,31(4):1211-1216.

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West China Medical Journal

成都地区常见过敏原致敏情况研究

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