• Department of Nosocomial Infection Management, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;
QIAOFu, Email: qiaofu2005@gmail.com
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Objective To investigate and analyze the antibiotic use in Sichuan Province. Methods Antibiotic use of inpatients was investigated in 23 hospitals on the day of June 25, 2011. Results The percentage of antibiotic use was 42.4% in the total 27 144 inpatients, the range of which was between 24.3% and 63.3% for each hospital. And 63.8% of the antibiotic use was for therapeutic purpose, and 72.2% used only one antibiotic drug. A total of 36.9% of the patients receiving antibiotic treatment for therapeutic use sent samples for pathogenic detection. With the increase of the size of the hospital (judged by the number of beds), antimicrobial drug utilization decreased with statistical significance (χ2=411.834, P=0.000). With the improvement of regional economic level (judged by per-capita GDP of each region), the hospital antimicrobial usage decreased with statistical significance (χ2=500.093, P=0.000). The three types of antimicrobial drug most frequently used were other β-lactam antibiotics, penicillin and third generation cephalosporin. Conclusion Antibiotic use is reasonable in Sichuan Province as a whole. However, it is necessary to reduce irrational use of antimicrobial agents continuously, and to strengthen the management of clinical antibiotic usage among inpatients.

Citation: HUANGWen-zhi, ZHUANGHong-di, LIShi-yu, QIAOFu, WANGYan-tong, YINWei-jia, ZONGZhi-yong, RAOLi. Survey and Analysis on Antibiotic Use from 23 Hospitals in Sichuan Province in 2011. West China Medical Journal, 2014, 29(3): 404-408. doi: 10.7507/1002-0179.20140123 Copy

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