CT Features of High-risk Gastrointestinal Stromal Tumors_West China Medical Journal

Authors：

 WANGEr-lei , JIAYu-jing , SHENJun-kang , GONGJianping , ZHUJian-bing ,  CHENGuang-qiang

Department of Radiology, the Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215004, P. R. China;

Corresponding author：

CHENGuang-qiang, Email: jyjkl@163.com

Keywords：

Gastrointestinal stromal tumor; Tomography, X-ray computed; High risk

DOI：

10.7507/1002-0179.20140396

Video：

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Abstract Full text Figures/Tables Video References Cited by

Objective To investigate the specific CT findings of high-risk gastrointestinal stromal tumors (GISTs). Methods CT findings of 24 patients with high-risk GISTs from August 2009 to March 2014 proved by surgery and pathology were retrospectively reviewed. Results Twelve of the high-risk GISTs were from the stomach, 11 from the small intestine (5 from duodenum, 4 from jejunum, and 2 from ileum), and 1 from the rectum. The biggest transverse diameter of the tumor was between 2.5 and 15.0 cm, and 2 were less than 5 cm and 22 of them were over 5 cm. The tumors appeared as irregular in 20 cases, and with indefinite boundary in 21 cases. Twenty-four tumors showed different levels of necrosis and cystic change, 15 showed ulcer, 2 showed perforation with effusion and pneumatosis, and 3 showed calcification. The enhancement of lesion was mostly moderately to markedly inhomogeneous. High-risk small intestinal stromal tumors had more significant enhancement and vessels. Hepatic metastasis in 3 cases was detected. Conclusion CT features of HRGISTs can be found with certain characteristics, which may contribute to the diagnosis.

Citation： WANGEr-lei, JIAYu-jing, SHENJun-kang, GONGJianping, ZHUJian-bing, CHENGuang-qiang. CT Features of High-risk Gastrointestinal Stromal Tumors. West China Medical Journal, 2014, 29(7): 1297-1300. doi: 10.7507/1002-0179.20140396 Copy

1.	Joensuu H. Risk stratification of patients diagnosed with gastrointestinal stromal tumor[J]. Hum Pathol, 2008, 39(10):1411-1419.
2.	Rammohan A, Sathyanesan J, Rajendran K, et al. A gist of gastrointestinal stromal tumors:a review[J]. World J Gastrointest Oncol, 2013, 5(6):102-112.
3.	Miettinen M, Lasota J. Gastrointestinal stromal tumors:review on morphology, molecular pathology, prognosis, and differential diagnosis[J]. Arch Pathol Lab Med, 2006, 130(10):1466-1478.
4.	吴奇新, 龙莉玲, 黄仲奎, 等. 胃肠道间质瘤的多层螺旋CT特征与其恶性危险度的相关性分析[J]. 实用放射学杂志, 2012, 28(6):891-895.
5.	Wong CS, Chu YC, Khong PL. Unusual features of gastrointestinal stromal tumor on PET/CT and CT imaging[J]. Clin Nucl Med, 2011, 36(3):e1-e7.
6.	Yang TH, Hwang JI, Yang MS, et al. Gastrointestinal stromal tumors:com puted tomographic features and prediction of malignant risk from computed tomographic imaging[J]. J Chin Med Assoc, 2007, 70(9):367-373.
7.	夏淦林, 冯峰, 李洪江, 等. 胃肠道间质瘤的影像学特征及侵袭危险的CT评价[J]. 实用放射学杂志, 2012, 28(11):1712-1716.
8.	王缉胜. 含气坏死腔在MSCT诊断间质瘤的价值及其病理基础[J]. 中国CT和MRI杂志, 2013, 11(2):75-77.
9.	Rimondini A, Belgrano M, Favretto G, et al. Contribution of CT to treatment planning in patients with GIST[J]. Radiol Med, 2007, 112(5):691-702.
10.	张华, 李锡林, 侯勤明, 等. 多层螺旋CT双期扫描对胃肠道间质瘤的诊断[J]. 实用放射学杂志, 2011, 27(3):401-403, 412.
11.	华广美, 尹化斌, 万凯明, 等. MSCT重建技术对小肠间质瘤的诊断价值[J]. 中国医学计算机成像杂志, 2013, 19(2):152-155.
12.	顾艳, 周胜利, 苗重昌. 不同侵袭危险度小肠间质瘤的MSCT表现[J]. 放射学实践, 2012, 27(10):1100-1104.
13.	孙烨, 綦维维. 多层螺旋CT半定量诊断高危险程度胃肠道间质瘤[J]. 中国医学影像技术, 2010, 26(3):517-520.
14.	宋晓丽, 方一, 吴正阳, 等. MSCT评价胃肠道间质瘤的恶性程度[J]. 中国医学影像技术, 2012, 28(10):1870-1873.
15.	Patnaik S, Jyotsnarani Y, Rammurti S. Radiological features of metastatic gastrointestinal stromal tumors[J]. J Clin Imaging Sci, 2012, 2(3):43.

1. Joensuu H. Risk stratification of patients diagnosed with gastrointestinal stromal tumor[J]. Hum Pathol, 2008, 39(10):1411-1419.
2. Rammohan A, Sathyanesan J, Rajendran K, et al. A gist of gastrointestinal stromal tumors:a review[J]. World J Gastrointest Oncol, 2013, 5(6):102-112.
3. Miettinen M, Lasota J. Gastrointestinal stromal tumors:review on morphology, molecular pathology, prognosis, and differential diagnosis[J]. Arch Pathol Lab Med, 2006, 130(10):1466-1478.
4. 吴奇新, 龙莉玲, 黄仲奎, 等. 胃肠道间质瘤的多层螺旋CT特征与其恶性危险度的相关性分析[J]. 实用放射学杂志, 2012, 28(6):891-895.
5. Wong CS, Chu YC, Khong PL. Unusual features of gastrointestinal stromal tumor on PET/CT and CT imaging[J]. Clin Nucl Med, 2011, 36(3):e1-e7.
6. Yang TH, Hwang JI, Yang MS, et al. Gastrointestinal stromal tumors:com puted tomographic features and prediction of malignant risk from computed tomographic imaging[J]. J Chin Med Assoc, 2007, 70(9):367-373.
7. 夏淦林, 冯峰, 李洪江, 等. 胃肠道间质瘤的影像学特征及侵袭危险的CT评价[J]. 实用放射学杂志, 2012, 28(11):1712-1716.
8. 王缉胜. 含气坏死腔在MSCT诊断间质瘤的价值及其病理基础[J]. 中国CT和MRI杂志, 2013, 11(2):75-77.
9. Rimondini A, Belgrano M, Favretto G, et al. Contribution of CT to treatment planning in patients with GIST[J]. Radiol Med, 2007, 112(5):691-702.
10. 张华, 李锡林, 侯勤明, 等. 多层螺旋CT双期扫描对胃肠道间质瘤的诊断[J]. 实用放射学杂志, 2011, 27(3):401-403, 412.
11. 华广美, 尹化斌, 万凯明, 等. MSCT重建技术对小肠间质瘤的诊断价值[J]. 中国医学计算机成像杂志, 2013, 19(2):152-155.
12. 顾艳, 周胜利, 苗重昌. 不同侵袭危险度小肠间质瘤的MSCT表现[J]. 放射学实践, 2012, 27(10):1100-1104.
13. 孙烨, 綦维维. 多层螺旋CT半定量诊断高危险程度胃肠道间质瘤[J]. 中国医学影像技术, 2010, 26(3):517-520.
14. 宋晓丽, 方一, 吴正阳, 等. MSCT评价胃肠道间质瘤的恶性程度[J]. 中国医学影像技术, 2012, 28(10):1870-1873.
15. Patnaik S, Jyotsnarani Y, Rammurti S. Radiological features of metastatic gastrointestinal stromal tumors[J]. J Clin Imaging Sci, 2012, 2(3):43.

West China Medical Journal

CT Features of High-risk Gastrointestinal Stromal Tumors

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