• Department of Neurological Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;
CHENMao-jun, Email: sjwkhl@163.com
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Objective To observe the treatment effects of zoledronic acid on postmenopausal osteoporosis. Methods Seventy-two postmenopausal osteoporosis patients from July 2007 to December 2010 were randomly divided into observation group and control group, with 36 patients in each. Traditional drug treatment was used in the control group, while traditional drug treatment and zoledronic acid were used for patients in the observation group. The Indicator of bone mineral density (BMD) and ostocalcin were used to comapre the treatment effects between the two groups after one-year treatment. Results There was a significant difference in BMD and osteocalcin in both the observation group and the control group before and after treatment (P<0.05). The treatment effect is superior in the observation group (P<0.05). Conclusion Zoledronic acid is an effective treatment for postmenopausal osteoporosis; it can increase BMD and osteocalcin more effectively.

Citation: LILi, WUXU-yi, CHENMao-jun. Clinical Efficacy of Zoledronic Acid on Postmenopausal Osteoporosis. West China Medical Journal, 2014, 29(12): 2312-2314. doi: 10.7507/1002-0179.20140699 Copy

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