The Image Quality Analysis and Control of Whole Body Tumor Imaging with <sup>18</sup>F-uorodeoxyglucose Positron Emission Tomography/Computer Tomography_West China Medical Journal

Authors：

 QIZhong-zhi ,  JIAZhi-yun

Department of Nuclear Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding author：

JIAZhi-yun, Email: amingjia@163.com

Keywords：

Positron emission tomography; Tomography; X-ray computed; ¹⁸F-deoxyglucose; Artifact; Quality Control; Post-processing technology

DOI：

10.7507/1002-0179.20150544

Video：

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Abstract Full text Figures/Tables Video References Cited by

Objective To analyze the influencing factors for image quality of 18F-deoxyglucose (FDG) positron emission tomography (PET)/CT systemic tumor imaging and explore the method of control in order to improve the PET/CT image quality. Methods Retrospective analysis of image data from March to June 2011 collected from 1 000 ¹⁸F-FDG whole body tumor imaging patients was carried out. We separated standard films from non-standard films according to PET/CT image quality criteria. Related factors for non-standard films were analyzed to explore the entire process quality control. Results There were 158 cases of standard films (15.80%), and 842 of non-standard films (84.20%). Artifact was a major factor for non-standard films (93.00%, 783/842) followed by patients’ injection information recording error (2.49%, 21/842), the instrument factor (1.90%, 16/842), incomplete scanning (0.95%, 8/842), muscle and soft tissue uptake (0.83%, 7/842), radionuclide contamination (0.59%, 5/842), and drug injection (0.24%, 2/842). The waste film rate was 5.80% (58/1 000), and the redoing rate was 2.20% (22/1 000). Conclusion Complex and diverse factors affect PET/CT image quality throughout the entire process, but most of them can be controlled if doctors, nurses and technicians coordinate and cooperate with each other. The rigorous routine quality control of equipment and maintenance, patients’ full preparation, appropriate position and scan field, proper parameter settings, and post-processing technology are important factors affecting the image quality.

Citation： QIZhong-zhi, JIAZhi-yun. The Image Quality Analysis and Control of Whole Body Tumor Imaging with ¹⁸F-uorodeoxyglucose Positron Emission Tomography/Computer Tomography. West China Medical Journal, 2015, 30(10): 1901-1905. doi: 10.7507/1002-0179.20150544 Copy

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1. Hany TF, Steinert HC, Goerres GW, et al. PET diagnostic accuracy: Improvement with in-line PET-CT system:initial results[J]. Radiology, 2002, 225(2):575-581.
2. Jackson J, Pan T, Tonkopi E, et al. Implementation of automated tube current modulation in PET/CT:prospective selection of a noise index and retrospective patient analysis to ensure image quality[J]. J Nucl Med Technol, 2011, 39(2):83-90.
3. 邓明. 核医学显像中注射技术误差分析及控制[J]. 现代临床医学生物工程学杂志, 2001, 7(3):225.
4. 贺小红. ¹⁸F-FDG正电子显像质量保证[J]. 国外医学:放射医学核医学分册, 2004, 28(5):193-196.
5. Shankar LK, Hoffman JM, Bacharach S, et al. Consensus recommendations for the use of ¹⁸F-FDG PET as an indicator of therapeutic response in patients in National Cancer Institute Trials[J]. J Nucl Med, 2006, 47(6):1059-1066.
6. Kawashita NH, Brito MN, Brito SR, et al. Glucose uptake, glucose transporter GLUT4, and glycolytic enzymes in brown adipose tissue from rats adapted to a high-protein diet[J]. Metabolism, 2002, 51(11):1501-1505.
7. Popilock R, Sandrasagaren K, Harris L, et al. CT artifact recognition for the nuclear technologist[J]. J Nucl Med Technol, 2008, 36(2): 79-81.
8. 陈泽龙, 谢康宁, 漆家学, 等. PET/CT图像基于CT衰减校正伪影的实验研究[J]. 医疗卫生装备, 2014, 34(3):81-84.
9. 郭悦, 秦嵩, 刘秀芹, 等. PET/CT图像膈肌上方条带状伪影特征及影响因素分析[J]. 医学研究杂志, 2013, 42(3):104-107.
10. Kawano T, Ohtake E, Inoue T. Deep-inspiration breath-hold PET/ CT of lung cancer:maximum standardized uptake value analysis of patients[J]. J Nucl Med, 2008, 49(8):1223-1231.
11. Meirelles GS, Erdi YE, Nehmeh SA, et al. Deep-inspiration breathhold PET/CT:clinical findings with a new technique for detection and characterization of thoracic lesions[J]. J Nucl Med, 2007, 48(5): 712-719.
12. Nehmeh SA, Erdi YE, Meirelles GS, et al. Deep-inspiration breathhold PET/CT of the thorax[J]. J Nucl Med, 2007, 48(1):22-26.
13. Grgic A, Nestle U, Schaefer-Schuler A, et al. FDG-PET-based radiotherapy planning in lung cancer:optimum breathing protocol and patient positioning——an intraindividual comparison[J]. Int J Radiat Oncol Biol Phys, 2009, 73(1):103-111.
14. De Juan R, Seifert B, Berthold T, et al. Clinical evaluation of a breathing protocol for PET/CT[J]. Eur Radiol, 2004, 14(6): 1118-1123.
15. Nehmeh SA, Erdi YE, Ling CC, et al. Effect of respiratory gating on quantifying PET images of lung cancer[J]. J Nucl Med, 2002, 43(7): 876-881.
16. Nehmeh SA, Erdi YE, Ling CC, et al. Effect of respiratory gating on reducing lung motion artifacts in PET imaging of lung cancer[J]. Med Phys, 2002, 29(3):366-371.
17. Nehmeh SA, Erdi YE, Pan T, et al. Four-dimensional (4D) PET/CT imaging of the thorax[J]. Med Phys, 2004, 31(12):3179-3186.
18. Nehmeh SA, Erdi YE, Pan T, et al. Quantitation of respiratory motion during 4D-PET/CT acquisition[J]. Med Phys, 2004, 31(6): 1333-1338.
19. Boucher L, Rodrigue S, Lecomte R, et al. Respiratory gating for 3-dimensional PET of the thorax:feasibility and initial results[J]. J Nucl Med, 2004, 45(2):214-219.
20. Nye JA, Esteves F, Votaw JR. Minimizing artifacts resulting from respiratory and cardiac motion by optimization of the transmission scan in cardiac PET/CT[J]. Med Phys, 2007, 34(6):1901-1906.

West China Medical Journal

The Image Quality Analysis and Control of Whole Body Tumor Imaging with ¹⁸F-uorodeoxyglucose Positron Emission Tomography/Computer Tomography

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The Image Quality Analysis and Control of Whole Body Tumor Imaging with ¹⁸F-uorodeoxyglucose Positron Emission Tomography/Computer Tomography