Research on the value of ultrasonography in the diagnosis of primary testicular lymphoma and the differential diagnosis_West China Medical Journal

Authors：

JING Wenli ¹ , SHA Xiaoxi ² , WANG Dongmei ¹ ,  LI Yongzhong ¹

1. Department of Ultrasonography, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;
2. Department of Ultrasonography, Affiliated Hospital of Chengdu University of TCM, Chengdu, Sichuan 610075, P. R. China;

Corresponding author：

LI Yongzhong, Email: ly917@126.com

Keywords：

Lymphoma; Testicular; Ultrasonography

DOI：

10.7507/1002-0179.201508103

Video：

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Objective To discuss the diagnostic and differential diagnostic value of ultrasonography for primary testicular lymphoma (PTL) by studying the ultrasonographical image characteristics. Methods Thirty-one patients with PTL confirmed by postoperative histopathology between 2005 and 2015 were chosen to be the study subjects. We retrospectively analyzed their ultrasonographical features and clinical data. Results Most PTL patients were elderly men, and the initial symptom was mainly painless testis enlargement. Thirty-nine testicles were involved in the primary testicular lymphoma, including 23 unilateral and 8 bilateral. In the 31 patients, 22 had diffuse lesions and 9 nodal. Ultrasonography showed that most tumors were hypoechoic lesions, and part of them were hyperechoic linearly. The lesions had abundant blood flow signals with a low resistance index. Conclusions In elderly patients with painless testicular enlargement, the possibility of primary testicular lymphoma must be fist considered. Manifestations of primary testicular lymphoma have some distinctive characteristics, and combined with clinical history, they are helpful for the diagnosis and differential diagnosis of PTL.

Citation： JING Wenli, SHA Xiaoxi, WANG Dongmei, LI Yongzhong. Research on the value of ultrasonography in the diagnosis of primary testicular lymphoma and the differential diagnosis. West China Medical Journal, 2017, 32(4): 567-570. doi: 10.7507/1002-0179.201508103 Copy

1.	娄丽丽, 岑溪南, 欧晋平, 等. 236例原发性结外淋巴瘤临床和病理分析. 中国实验血液学杂志, 2014, 22(1): 85-92.
2.	Zucca E, Conconi A, Mughal TI, et al. Patterns of outcome and prognostic factors in primary large-cell lymphoma of the testis in a survey by the International Extranodal Lymphoma Study Group. J Clin Oncol, 2003, 21(1): 20-27.
3.	Shahab N, Doll DC. Testicular lymphoma. Semin Oncol, 1999, 26(3): 259-269.
4.	Cheah CY, Wirth A, Seymour JF. Primary testicular lymphoma. Blood, 2014, 123(4): 486-493.
5.	Vitolo U, Ferreri AJ, Zucca E, et al. Primary testicular lymphoma. Crit Rev Oncol Hematol, 2008, 65(2): 183-189.
6.	Tondini C, Ferreri AJ, Siracusano L, et al. Diffuse large-cell lymphoma of the testis. J Clin Oncol, 1999, 17(9): 2854-2858.
7.	朱一辰, 肖荆, 郭宇文, 等. 原发性睾丸淋巴瘤 17 例的诊治体会. 国际外科学杂志, 2012, 39(6): 377-379.
8.	Zouhair A, Weber D, Belkacé mi Y, et al. Outcome and patterns of failure in testicular lymphoma: a multicenter Rare Cancer Network study. Int J Radiat Oncol Biol Phys, 2002, 52(3): 652-656.
9.	Lagrange JL, Ramaioli A, Theodore CH, et al. Non-Hodgkin’s lymphoma of the testis: a retrospective study of 84 patients treated in the French anticancer centres. Ann Oncol, 2001, 12(9): 1313-1319.
10.	何川, 蔡迪明, 刘霆. 睾丸淋巴瘤的超声影像学和临床特点及文献复习. 中国医学影像技术, 2007, 23(4): 592-594.
11.	聂宝, 黄欣, 刘校龙, 等. 65 例睾丸非霍奇金淋巴瘤的临床病理学特征. 中华血液学杂志, 2015, 36(9): 765-769.
12.	Zicherman JM, Weissman D, Gribbin C, et al. Best cases from the AFIP: primary diffuse large B-cell lymphoma of the epididymis and testis. Radiographics, 2005, 25(1): 243-248.
13.	Booman M, Douwes J, Glas AM, et al. Primary testicular diffuse large B-cell lymphomas have activated B-cell-like subtype characteristics. J Pathol, 2006, 210(2): 163-171.
14.	赵海军, 姚福生, 钟龙. 原发睾丸弥漫大 B 细胞淋巴瘤心脏侵犯一例. 中华血液学杂志, 2014, 35(8): 770.
15.	王振华, 楮雯, 寇育红, 等. 高频彩色多普勒超声对原发性睾丸淋巴瘤的诊断价值及误诊分析. 中国男科学杂志, 2015, 29(9): 46-48, 52.
16.	Dogra VS, Gottlieb RH, Oka M, et al. Sonography of the scrotum. Radiology, 2003, 227(1): 18-36.
17.	陈舜, 薛恩生, 林礼务, 等. 彩色多普勒超声在睾丸生殖细胞瘤诊断中的价值. 中华医学超声杂志: 电子版, 2006, 3(4): 229-231.
18.	Mazzu D, Jeffrey RB, Ralls PW. Lymphoma and leukemia involving the testicles: findings on gray-scale and color Doppler sonography. AJR Am J Roentgenol, 1995, 164(3): 645-647.

1. 娄丽丽, 岑溪南, 欧晋平, 等. 236例原发性结外淋巴瘤临床和病理分析. 中国实验血液学杂志, 2014, 22(1): 85-92.
2. Zucca E, Conconi A, Mughal TI, et al. Patterns of outcome and prognostic factors in primary large-cell lymphoma of the testis in a survey by the International Extranodal Lymphoma Study Group. J Clin Oncol, 2003, 21(1): 20-27.
3. Shahab N, Doll DC. Testicular lymphoma. Semin Oncol, 1999, 26(3): 259-269.
4. Cheah CY, Wirth A, Seymour JF. Primary testicular lymphoma. Blood, 2014, 123(4): 486-493.
5. Vitolo U, Ferreri AJ, Zucca E, et al. Primary testicular lymphoma. Crit Rev Oncol Hematol, 2008, 65(2): 183-189.
6. Tondini C, Ferreri AJ, Siracusano L, et al. Diffuse large-cell lymphoma of the testis. J Clin Oncol, 1999, 17(9): 2854-2858.
7. 朱一辰, 肖荆, 郭宇文, 等. 原发性睾丸淋巴瘤 17 例的诊治体会. 国际外科学杂志, 2012, 39(6): 377-379.
8. Zouhair A, Weber D, Belkacé mi Y, et al. Outcome and patterns of failure in testicular lymphoma: a multicenter Rare Cancer Network study. Int J Radiat Oncol Biol Phys, 2002, 52(3): 652-656.
9. Lagrange JL, Ramaioli A, Theodore CH, et al. Non-Hodgkin’s lymphoma of the testis: a retrospective study of 84 patients treated in the French anticancer centres. Ann Oncol, 2001, 12(9): 1313-1319.
10. 何川, 蔡迪明, 刘霆. 睾丸淋巴瘤的超声影像学和临床特点及文献复习. 中国医学影像技术, 2007, 23(4): 592-594.
11. 聂宝, 黄欣, 刘校龙, 等. 65 例睾丸非霍奇金淋巴瘤的临床病理学特征. 中华血液学杂志, 2015, 36(9): 765-769.
12. Zicherman JM, Weissman D, Gribbin C, et al. Best cases from the AFIP: primary diffuse large B-cell lymphoma of the epididymis and testis. Radiographics, 2005, 25(1): 243-248.
13. Booman M, Douwes J, Glas AM, et al. Primary testicular diffuse large B-cell lymphomas have activated B-cell-like subtype characteristics. J Pathol, 2006, 210(2): 163-171.
14. 赵海军, 姚福生, 钟龙. 原发睾丸弥漫大 B 细胞淋巴瘤心脏侵犯一例. 中华血液学杂志, 2014, 35(8): 770.
15. 王振华, 楮雯, 寇育红, 等. 高频彩色多普勒超声对原发性睾丸淋巴瘤的诊断价值及误诊分析. 中国男科学杂志, 2015, 29(9): 46-48, 52.
16. Dogra VS, Gottlieb RH, Oka M, et al. Sonography of the scrotum. Radiology, 2003, 227(1): 18-36.
17. 陈舜, 薛恩生, 林礼务, 等. 彩色多普勒超声在睾丸生殖细胞瘤诊断中的价值. 中华医学超声杂志: 电子版, 2006, 3(4): 229-231.
18. Mazzu D, Jeffrey RB, Ralls PW. Lymphoma and leukemia involving the testicles: findings on gray-scale and color Doppler sonography. AJR Am J Roentgenol, 1995, 164(3): 645-647.

West China Medical Journal

Research on the value of ultrasonography in the diagnosis of primary testicular lymphoma and the differential diagnosis

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