Experience of Treating Multiple Liver Cancer by Liver Resection Combined with Intraoperative Radiofrequency Ablation in the Same Period_West China Medical Journal

Authors：

 PengYonghai ¹ , ChenSirui ¹ ,  HuZhaohui ¹ , LuoHua ¹ , GuoDaoning ²

1. Department of Hepatobiliary Surgery, Mianyang Central Hospital, Mianyang, Sichuan 621000, P. R. China;
2. Department of Ultrasound, Mianyang Central Hospital, Mianyang, Sichuan 621000, P. R. China;

Corresponding author：

HuZhaohui, Email: huzhaohui.sc@163.com

Keywords：

Multiple liver cancer; Liver resection; Radiofrequency ablation; Ultrasonography

DOI：

10.7507/1002-0179.201600334

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To explore the value liver resection combined with intraoperative radiofrequency ablation during the same period in the treatment of multiple liver cancer. Methods We retrospectively analyzed the clinical data of 33 patients with multiple liver cancer treated between January 2005 and April 2013. All the patients were treated by liver resection combined with intraoperative radiofrequency ablation in the same period. There were 91 tumor foci in 33 patients, among which 39 tumor foci were surgically removed, and 52 tumor foci were radiofrequency ablated. Ultrasonography and enhanced CT/MRI were performed for the patients 1 year, 2 years and 3 years after surgery. Results No bleeding or death occurred during the operation. It was observed that the transient liver function was damaged after surgery, but it quickly returned to A level after treatment. All the patients had no perioperative death or other serious complications. Tumor recurrence rate was 16.1% in the first year, 48.4% in the second year and 93.5% in the third year after surgery. Conclusion Liver resection combined with intraoperative radiofrequency ablation for multiple liver cancer in the same period is feasible and safe, without increasing the average length of hospital stay, operative mortality rate and postoperative tumor recurrence rate.

Citation： PengYonghai, ChenSirui, HuZhaohui, LuoHua, GuoDaoning. Experience of Treating Multiple Liver Cancer by Liver Resection Combined with Intraoperative Radiofrequency Ablation in the Same Period. West China Medical Journal, 2016, 31(7): 1227-1230. doi: 10.7507/1002-0179.201600334 Copy

1.	陈孝平, 汪建平. 外科学[M]. 8版. 北京:人民卫生出版社, 2013:432-435.
2.	Chen MS, Li JQ, Zheng Y, et al. A prospective randomized trial comparing percutaneous local ablative therapy and partial hepatectomy for small hepatocellular carcinoma[J]. Ann Surg, 2006, 243(3):321-328.
3.	Beeres M, Loch M, Schulz B, et al. Bolus timing in high-pitch CT angiography:feasibility study[J]. Euro J Radiol, 2013, 82(6):1028-1033.
4.	Tatsugami F, Matsuki M, Inada Y, et al. Feasibility of low-volume injections of contrast material with a body weight-adapted iodine-dose protocol in 320-detector row coronary CT angiography[J]. Acad Radiol, 2010, 17(2):207-211.
5.	El-Serag HB, Marrero JA, Rudolph L, et al. Diagnosis and treatment of hepatocelluar carcinoma[J]. Gastroenterology, 2008, 134(6):1752-1763.
6.	Takayama T, Makuuchi M, Hirohashi S, et al. Early hepatocellular carcinoma as an entity with a high rate of surgical cure[J]. Hepatology, 1998, 28(5):1241-1246.
7.	Schiff ER, Sorrell MF, Maddrey WC. 希夫肝脏病学[M]. 北京:化学工业出版社, 2006:1240-1241.
8.	杨学伟, 将小峰, 曹良启, 等. 肝切除联合射频消融治疗多发性肝癌36例疗效分析[J]. 实用医学杂志, 2013, 29(11):1820-1822.
9.	覃夏川, 周翔. 肝叶切除联合术中超声引导射频消融治疗多发性肝癌的价值[J]. 临床超声医学杂志, 2013, 15(10):713-714.
10.	冯钜涛, 李君, 方天翎, 等. 肝切除并微波消融与TACE治疗多发性肝癌的疗效比较[J]. 广州医学院学报, 2012, 40(2):41-44.
11.	朱倩, 乔国梁, 晏建军, 等. 乙肝肝硬化相关早期肝癌切除术预后[J]. 中华肝胆外科杂志, 2014, 20(4):258-264.
12.	彭国文, 李晓群. 射频消融及组合方案治疗特殊/高危部位肝癌的中远期疗效[J]. 介入放射学杂志, 2013, 22(6):525-528.
13.	张辉, 徐新保, 何晓军, 等. 原发性肝癌术后复发再手术切除与射频消融治疗的疗效比较[J]. 西部医学, 2013, 25(12):1816-1818.
14.	吴孟超. 原发性肝癌外科综合治疗的现状和展望[J]. 中华外科杂志, 2004, 42(1):13-15.
15.	张城硕, 富大智, 张佳林, 等. 复发性小肝癌视频与再次手术切除临床疗效的Meta分析[J]. 中华肝胆外科杂志, 2014, 20(4):248-252.

1. 陈孝平, 汪建平. 外科学[M]. 8版. 北京:人民卫生出版社, 2013:432-435.
2. Chen MS, Li JQ, Zheng Y, et al. A prospective randomized trial comparing percutaneous local ablative therapy and partial hepatectomy for small hepatocellular carcinoma[J]. Ann Surg, 2006, 243(3):321-328.
3. Beeres M, Loch M, Schulz B, et al. Bolus timing in high-pitch CT angiography:feasibility study[J]. Euro J Radiol, 2013, 82(6):1028-1033.
4. Tatsugami F, Matsuki M, Inada Y, et al. Feasibility of low-volume injections of contrast material with a body weight-adapted iodine-dose protocol in 320-detector row coronary CT angiography[J]. Acad Radiol, 2010, 17(2):207-211.
5. El-Serag HB, Marrero JA, Rudolph L, et al. Diagnosis and treatment of hepatocelluar carcinoma[J]. Gastroenterology, 2008, 134(6):1752-1763.
6. Takayama T, Makuuchi M, Hirohashi S, et al. Early hepatocellular carcinoma as an entity with a high rate of surgical cure[J]. Hepatology, 1998, 28(5):1241-1246.
7. Schiff ER, Sorrell MF, Maddrey WC. 希夫肝脏病学[M]. 北京:化学工业出版社, 2006:1240-1241.
8. 杨学伟, 将小峰, 曹良启, 等. 肝切除联合射频消融治疗多发性肝癌36例疗效分析[J]. 实用医学杂志, 2013, 29(11):1820-1822.
9. 覃夏川, 周翔. 肝叶切除联合术中超声引导射频消融治疗多发性肝癌的价值[J]. 临床超声医学杂志, 2013, 15(10):713-714.
10. 冯钜涛, 李君, 方天翎, 等. 肝切除并微波消融与TACE治疗多发性肝癌的疗效比较[J]. 广州医学院学报, 2012, 40(2):41-44.
11. 朱倩, 乔国梁, 晏建军, 等. 乙肝肝硬化相关早期肝癌切除术预后[J]. 中华肝胆外科杂志, 2014, 20(4):258-264.
12. 彭国文, 李晓群. 射频消融及组合方案治疗特殊/高危部位肝癌的中远期疗效[J]. 介入放射学杂志, 2013, 22(6):525-528.
13. 张辉, 徐新保, 何晓军, 等. 原发性肝癌术后复发再手术切除与射频消融治疗的疗效比较[J]. 西部医学, 2013, 25(12):1816-1818.
14. 吴孟超. 原发性肝癌外科综合治疗的现状和展望[J]. 中华外科杂志, 2004, 42(1):13-15.
15. 张城硕, 富大智, 张佳林, 等. 复发性小肝癌视频与再次手术切除临床疗效的Meta分析[J]. 中华肝胆外科杂志, 2014, 20(4):248-252.

Previous Article
Local Infiltration Analgesia for Postoperative Pain after Hip Arthroplasty: A Meta-analysis
Next Article
Effect of Dexmedetomidine-parecoxib Sodium on Postoperative Cognitive Function

West China Medical Journal

Experience of Treating Multiple Liver Cancer by Liver Resection Combined with Intraoperative Radiofrequency Ablation in the Same Period

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content