Effect of Drug Management Skill Training on Lightening the Family Burden of Schizophrenic Patients in the Recovery Period_West China Medical Journal

Authors：

 ZuoXiaofeng , WuShuang , LiuYi , LiShuiying , ZhouQian , LaiHua ,  ZhangZhuoqiu

Psychological Health Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding author：

ZhangZhuoqiu, Email: zhuoqiuzh@126.com

Keywords：

Schizophrenia; Drug management skill training; Positive and negative syndrome scale; Family burden scale of diseases

DOI：

10.7507/1002-0179.20160038

Video：

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Objective To explore the effects of drug management skill training on lightening the family burden of schizophrenic patients in their recovery period. Methods Between December 2011 and December 2013, 101 patients with schizophrenia were randomly divided into experimental group (n=56) and control group (n=45). The experimental group was given drug management skill training, while the control group only received routine follow-up. The course of the research was six months. Both groups were assessed by the positive and negative syndrome scale on patients' psychological symptoms, and family burden scale of diseases was used to assess the burden of the family. Results Compared with the controls, patients in the experimental group improved more in their positive symptoms (t=2.692, P=0.008), negative symptoms (t=2.729, P=0.008), general psychopathology symptoms (t=3.231, P=0.002) and the whole psychiatric symptoms (t=3.870, P<0.001). Moreover, the degree of patients' symptom improvement was positively correlated with the degree of family burden lightening (r=0.44, P<0.001). Conclusion For patients with schizophrenia, reasonable drug management skill training can effectively improve patients' medication compliance, promote treatment effect and lighten family burden.

Citation： ZuoXiaofeng, WuShuang, LiuYi, LiShuiying, ZhouQian, LaiHua, ZhangZhuoqiu. Effect of Drug Management Skill Training on Lightening the Family Burden of Schizophrenic Patients in the Recovery Period. West China Medical Journal, 2016, 31(1): 135-138. doi: 10.7507/1002-0179.20160038 Copy

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2.	Klingberg S, Schneider S, Wittorf A, et al. Collaboration in outpatient antipsychotic drug treatment:analysis of potentially influencing factors[J]. Psychiatry Res, 2008, 161(2):225-234.
3.	Pi WD, Olfson M. Cost of relapse in schizophrenia[J]. Schizophr Bull, 1995, 21(3):419-429.
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7.	张作记. 行为医学量表手册[M/CD]. 北京:中华医学电子音像出版社, 2005:97-359.
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9.	魏春香, 楚平华, 魏贵明. 对住院精神分裂症患者自我管理训练康复效果的评价[J]. 现代护理, 2007, 13(25):2367-2369.
10.	杨彩儒, 刘建丛, 安欣儒. 首发精神分裂症患者服药依从性的调查[J]. 护理实践与研究, 2011, 8(1):123-124.
11.	裴建琴, 张瑞芬, 梅文卓. 康复期精神分裂症患者的药物管理技能训练[J]. 护理学杂志, 2009, 24(15):74-76.
12.	杨彩霞. 精神疾病患者药物管理训练概述[J]. 国际精神病学杂志, 2011, 38(3):181-184.
13.	周湘梅, 马莹, 吴虹. 药物管理训练应用于精神分裂症患者后服药效果观察[J]. 护理学报, 2014, 21(15):58-60.
14.	黄秀梅, 黄雪花, 黄丽娟, 等. 家庭关怀对精神分裂症患者生活质量的影响[J]. 华西医学, 2014, 29(12):2275-2278.
15.	陈爱学, 苏雅芳, 姚明荣, 等. 精神病患者家属心理应激与家庭负担和心理健康状况的相关性研究[J]. 护理与康复, 2015, 14(4):311-314, 318.
16.	王文伶, 蔡亲奕, 伍雪晶. 心理干预对精神分裂症患者家属焦虑抑郁情绪的影响[J]. 广东医学, 2014, 35(2):315-317.
17.	Möller-leimkühler AM. Burden of relatives and predictors of burden. Baseline results from the Munich 5-year-follow-up study on relatives of first hospitalized patients with schizophrenia or depression[J]. Eur Arch Psychiatry Clin Neurosci, 2005, 255(4): 223-231.
18.	谢侃侃, 张国富, 李艳, 等. 北京城区精神分裂症家属经济负担与生存质量[J]. 临床精神医学杂志, 2011, 21(2):84-86.

1. Gilbert PL, Harris MJ, Mcadams LA, et al. Neuroleptic withdrawal in schizophrenic patients. A review of the literature[J]. Arch Gen Psychiatry, 1995, 52(3):173-188.
2. Klingberg S, Schneider S, Wittorf A, et al. Collaboration in outpatient antipsychotic drug treatment:analysis of potentially influencing factors[J]. Psychiatry Res, 2008, 161(2):225-234.
3. Pi WD, Olfson M. Cost of relapse in schizophrenia[J]. Schizophr Bull, 1995, 21(3):419-429.
4. 刘国强. 药物管理技能训练对精神分裂症患者服药依从性的影响[J]. 齐齐哈尔医学院学报, 2013, 34(14):2155-2156.
5. 林连英. 药物管理技能训练对精神分裂症患者服药依从性的影响[J]. 中国医学创新, 2013, 10(2):86.
6. 裴建琴, 张瑞芬, 梅文卓. 药物管理技能训练对精神分裂症病人服药依从性的影响[J]. 护理研究, 2010, 24(3):219-220.
7. 张作记. 行为医学量表手册[M/CD]. 北京:中华医学电子音像出版社, 2005:97-359.
8. Woods SW. Chlorpromazine equivalent doses for the newer atypical antipsychotics[J]. J Clin Psychiatry, 2003, 64(6):663-667.
9. 魏春香, 楚平华, 魏贵明. 对住院精神分裂症患者自我管理训练康复效果的评价[J]. 现代护理, 2007, 13(25):2367-2369.
10. 杨彩儒, 刘建丛, 安欣儒. 首发精神分裂症患者服药依从性的调查[J]. 护理实践与研究, 2011, 8(1):123-124.
11. 裴建琴, 张瑞芬, 梅文卓. 康复期精神分裂症患者的药物管理技能训练[J]. 护理学杂志, 2009, 24(15):74-76.
12. 杨彩霞. 精神疾病患者药物管理训练概述[J]. 国际精神病学杂志, 2011, 38(3):181-184.
13. 周湘梅, 马莹, 吴虹. 药物管理训练应用于精神分裂症患者后服药效果观察[J]. 护理学报, 2014, 21(15):58-60.
14. 黄秀梅, 黄雪花, 黄丽娟, 等. 家庭关怀对精神分裂症患者生活质量的影响[J]. 华西医学, 2014, 29(12):2275-2278.
15. 陈爱学, 苏雅芳, 姚明荣, 等. 精神病患者家属心理应激与家庭负担和心理健康状况的相关性研究[J]. 护理与康复, 2015, 14(4):311-314, 318.
16. 王文伶, 蔡亲奕, 伍雪晶. 心理干预对精神分裂症患者家属焦虑抑郁情绪的影响[J]. 广东医学, 2014, 35(2):315-317.
17. Möller-leimkühler AM. Burden of relatives and predictors of burden. Baseline results from the Munich 5-year-follow-up study on relatives of first hospitalized patients with schizophrenia or depression[J]. Eur Arch Psychiatry Clin Neurosci, 2005, 255(4): 223-231.
18. 谢侃侃, 张国富, 李艳, 等. 北京城区精神分裂症家属经济负担与生存质量[J]. 临床精神医学杂志, 2011, 21(2):84-86.

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West China Medical Journal

Effect of Drug Management Skill Training on Lightening the Family Burden of Schizophrenic Patients in the Recovery Period

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