Comparison between ultrasonic manifestations and pathologic findings of soft tissue myxoid liposarcoma_West China Medical Journal

Authors：

ZOU Xiaopan ^1,2 , XIANG Xi ¹ ,  QIU Li ¹

1. Department of Ultrasonic Diagnosis, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;
2. Department of Ultrasonography, Mianyang Central Hospital, Mianyang, Sichuan 621000, P. R. China;

Corresponding author：

QIU Li, Email: wsqiuli@126.com

Keywords：

Myxoid liposarcoma; Soft tissue; Ultrasonography; Pathology

DOI：

10.7507/1002-0179.201608288

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Objective To analyze the ultrasonic manifestations of myxoid liposarcoma (MLS) in soft tissues.Methods We retrospectively analyzed the ultrasonic characteristics of 10 cases of soft tissue MLS which were pathologically confirmed between January and June 2006. Results Ultrasonic manifestations: 8 cases occurred in muscles and 2 in subcutaneous tissues and muscles; the maximum mass diameter was (71.1±39.4) mm; 10 cases had clear border, 8 had regular shape, and 9 had posterior echo enhancement; 10 cases were all solid masses with mucous liquid zone (9 cases had mainly weak echo, among which 5 had strong echo areas; 1 case had mainly strong echo); bloodstream grade: 3 cases belonged to level 0, 3 level Ⅰ, 2 level Ⅱ, and 2 level Ⅲ. Pathologic findings: 2 cases had low differentiation; 1 case was a mixture of MLS and atypical lipoma with mainly strong ultrasonic echo; the rest 7 cases had middle or high differentiation.Conclusions Ultrasonic manifestations of soft tissue MLS are mostly large masses in the muscular layer with clear border, regular shape, posterior echo enhancement and mucous liquid zone. Various degrees of strong echo zone exist in the masses. Bloodstream and mucous liquid zone are correlated with differentiation degree, and ultrasonic manifestations can be influenced if other factors exist.

Citation： ZouXiaopan, XiangXi, QIULi. Comparison between ultrasonic manifestations and pathologic findings of soft tissue myxoid liposarcoma. West China Medical Journal, 2017, 32(2): 204-208. doi: 10.7507/1002-0179.201608288 Copy

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2.	Pellizzon AC. Evidence and clinical outcomes of adult soft tissue sarcomas of the extremities treated with adjuvant high-dose-rate brachytherapy - a literature review. J Contemp Brachytherapy, 2014, 6(3): 318-322.
3.	Wortman R, Tirumani H, Jagannathan P, et al. Primary extremity liposarcoma: MRI features, histopathology, and clinical outcomes. J Comput Assist Tomogr, 2016, 40(5): 791-798.
4.	朱雄增. 软组织肿瘤 WHO 最新分类特点. 临床与实验病理学杂志, 2003, 19(1): 94-96.
5.	Rizer M, Singer D, Edgar M, et al. The histological variants of liposarcoma: predictive MRI findings with prognostic implications, management, follow-up, and differential diagnosis. Skeletal Radiol, 2016, 45(9): 1193-1204.
6.	Mankin J, Mankin P, Harmon C. Liposarcoma: a soft tissue tumor with many presentations. Musculoskelet Surg, 2014, 98(3): 171-177.
7.	Lu J, Qin Q, Zhan L, et al. Computed tomography manifestations of histologic subtypes of retroperitoneal liposarcoma. Asian Pac J Cancer Prev, 2014, 15(15): 6041-6046.
8.	Löwenthal D, Zeile M, Niederhagen M, et al. Differentiation of myxoid liposarcoma by magnetic resonance imaging: a histopathologic correlation. Acta Radiol, 2014, 55(8): 952-960.
9.	Bekers EM, Song W, Suurmeijer AJ, et al. Myxoid liposarcoma of the foot: a study of 8 cases. Ann Diagn Pathol, 2016, 25: 37-41.
10.	El Ouni F, Jemni H, Trabelsi A, et al. Liposarcoma of the extremities: Mr imaging features and their correlation with pathologic data. Orthop Traumatol Surg Res, 2010, 96(8): 876-883.
11.	Inampudi P, Jacobson A, Fessell P, et al. Soft-tissue lipomas: accuracy of sonography in diagnosis with pathologic correlation. Radiology, 2004, 233(3): 763-767.
12.	曾佳, 唐远姣, 邱逦. 肌内黏液瘤超声影像特征. 中国医学影像技术, 2015, 31(3): 446-449.
13.	Gronchi A, Lo Vullo S, Colombo C, et al. Extremity soft tissue sarcoma in a series of patients treated at a single institution: local control directly impacts survival. Ann Surg, 2010, 251(3): 506-511.
14.	敬文莉, 彭玉兰, 王冬梅. 超声对软组织淋巴瘤的诊断价值. 华西医学, 2016, 31(3): 523-526.
15.	杨磊. 彩色多普勒超声对肾脏神经鞘瘤的诊断价值. 华西医学, 2016, 31(1): 79-81.

1. Piperi E, Tosios I, Nikitakis G, et al. Well-differentiated liposarcoma/atypical lipomatous tumor of the oral cavity: report of three cases and review of the literature. Head Neck Pathol, 2012, 6(3): 354-363.
2. Pellizzon AC. Evidence and clinical outcomes of adult soft tissue sarcomas of the extremities treated with adjuvant high-dose-rate brachytherapy - a literature review. J Contemp Brachytherapy, 2014, 6(3): 318-322.
3. Wortman R, Tirumani H, Jagannathan P, et al. Primary extremity liposarcoma: MRI features, histopathology, and clinical outcomes. J Comput Assist Tomogr, 2016, 40(5): 791-798.
4. 朱雄增. 软组织肿瘤 WHO 最新分类特点. 临床与实验病理学杂志, 2003, 19(1): 94-96.
5. Rizer M, Singer D, Edgar M, et al. The histological variants of liposarcoma: predictive MRI findings with prognostic implications, management, follow-up, and differential diagnosis. Skeletal Radiol, 2016, 45(9): 1193-1204.
6. Mankin J, Mankin P, Harmon C. Liposarcoma: a soft tissue tumor with many presentations. Musculoskelet Surg, 2014, 98(3): 171-177.
7. Lu J, Qin Q, Zhan L, et al. Computed tomography manifestations of histologic subtypes of retroperitoneal liposarcoma. Asian Pac J Cancer Prev, 2014, 15(15): 6041-6046.
8. Löwenthal D, Zeile M, Niederhagen M, et al. Differentiation of myxoid liposarcoma by magnetic resonance imaging: a histopathologic correlation. Acta Radiol, 2014, 55(8): 952-960.
9. Bekers EM, Song W, Suurmeijer AJ, et al. Myxoid liposarcoma of the foot: a study of 8 cases. Ann Diagn Pathol, 2016, 25: 37-41.
10. El Ouni F, Jemni H, Trabelsi A, et al. Liposarcoma of the extremities: Mr imaging features and their correlation with pathologic data. Orthop Traumatol Surg Res, 2010, 96(8): 876-883.
11. Inampudi P, Jacobson A, Fessell P, et al. Soft-tissue lipomas: accuracy of sonography in diagnosis with pathologic correlation. Radiology, 2004, 233(3): 763-767.
12. 曾佳, 唐远姣, 邱逦. 肌内黏液瘤超声影像特征. 中国医学影像技术, 2015, 31(3): 446-449.
13. Gronchi A, Lo Vullo S, Colombo C, et al. Extremity soft tissue sarcoma in a series of patients treated at a single institution: local control directly impacts survival. Ann Surg, 2010, 251(3): 506-511.
14. 敬文莉, 彭玉兰, 王冬梅. 超声对软组织淋巴瘤的诊断价值. 华西医学, 2016, 31(3): 523-526.
15. 杨磊. 彩色多普勒超声对肾脏神经鞘瘤的诊断价值. 华西医学, 2016, 31(1): 79-81.

West China Medical Journal

Comparison between ultrasonic manifestations and pathologic findings of soft tissue myxoid liposarcoma

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