<trans-title xml:lang="en"/>_West China Medical Journal

Authors：

乔甫 , 卫丽 , 庄红娣 , 林吉 , 黄文治 ,  尹维佳

四川大学华西医院医院感染管理部（成都 610041）;

Corresponding author：

尹维佳, Email: 525989261@qq.com

Keywords：

速干手消毒剂; 洗必泰; 多重耐药菌; 悬液定量杀菌试验

DOI：

10.7507/1002-0179.201701155

Video：

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目的评价含氯己定醇的速干手消毒液对临床常见的多重耐药菌（multidrug-resistant organism，MDRO）的杀灭效果。方法选用 2015 年 1 月—12 月临床分离到的耐碳青霉烯鲍曼不动杆菌、耐甲氧西林金黄色葡萄球菌和耐万古霉素肠球菌各 30 株，耐碳青霉烯大肠埃希菌和耐碳青霉烯肺炎克雷伯菌各 15 株，采用悬液定量杀菌试验，查看该消毒液分别作用目标菌悬液 15、30、60 s 后的杀灭效果。结果试验的各类 MDRO 平均回收菌落均在（1～5）×10⁸ cfu/mL，用试验消毒液作用 15、30、60 s 后，杀灭对数值均≥5。结论含氯己定醇的速干手消毒液作用 15 s 能有效杀灭临床常见的 MDRO，满足临床实际操作的需求。

Citation： 乔甫, 卫丽, 庄红娣, 林吉, 黄文治, 尹维佳. . West China Medical Journal, 2017, 32(3): 375-376. doi: 10.7507/1002-0179.201701155 Copy

1.	Pincock T, Bernstein P, Warthman S, et al. Bundling hand hygiene interventions and measurement to decrease health care-associated infections. Am J Infect Control, 2012, 40(4 Suppl 1): S18-S27.
2.	Hansen S, Schwab F, Gastmeier P, et al. Provision and consumption of alcohol-based hand rubs in European hospitals. Clin Microbiol Infect, 2015, 21(12): 1047-1051.
3.	WHO. Guidelines on hand hygiene in health care. Geneva, Switzerland: World Health Organization Press, 2009. .
4.	中华人民共和国卫生部. WS/T 313—2009 医务人员手卫生规范, 2009.
5.	中华人民共和国国家卫生和计划生育委员会. 卫生部关于印发《消毒技术规范》(2002年版) 的通知. (2002-11-25)[2006-02-09]. .
6.	Souweine B, Lautrette A, Aumeran C, et al. Comparison of acceptability, skin tolerance, and compliance between handwashing and alcohol-based handrub in ICUs: results of a multicentric study. Intensive Care Med, 2009, 35(7): 1216-1224.
7.	Salmon S, Truong AT, Nguyen VH, et al. Health care workers’ hand contamination levels and antibacterial efficacy of different hand hygiene methods used in a Vietnamese hospital. Am J Infect Control, 2014, 42(2): 178-181.
8.	周凤莲, 杨莉娜, 余阳, 等. 速干性手消毒剂对医院感染致病菌杀灭效果. 中国消毒学杂志, 2010, 27(6): 673-674.
9.	周凤莲, 杨莉娜, 余阳, 等. 常用消毒剂对部分多重耐药菌杀灭效果的观察. 中国消毒学杂志, 2013, 30(9): 808-810.
10.	李春梅, 钟晓祝, 杨金城. 葡萄糖酸氯己定醇皮肤消毒液对多药耐药菌的杀菌效果评价. 中华医院感染学杂志, 2013, 23(3): 610-611.

1. Pincock T, Bernstein P, Warthman S, et al. Bundling hand hygiene interventions and measurement to decrease health care-associated infections. Am J Infect Control, 2012, 40(4 Suppl 1): S18-S27.
2. Hansen S, Schwab F, Gastmeier P, et al. Provision and consumption of alcohol-based hand rubs in European hospitals. Clin Microbiol Infect, 2015, 21(12): 1047-1051.
3. WHO. Guidelines on hand hygiene in health care. Geneva, Switzerland: World Health Organization Press, 2009. .
4. 中华人民共和国卫生部. WS/T 313—2009 医务人员手卫生规范, 2009.
5. 中华人民共和国国家卫生和计划生育委员会. 卫生部关于印发《消毒技术规范》(2002年版) 的通知. (2002-11-25)[2006-02-09]. .
6. Souweine B, Lautrette A, Aumeran C, et al. Comparison of acceptability, skin tolerance, and compliance between handwashing and alcohol-based handrub in ICUs: results of a multicentric study. Intensive Care Med, 2009, 35(7): 1216-1224.
7. Salmon S, Truong AT, Nguyen VH, et al. Health care workers’ hand contamination levels and antibacterial efficacy of different hand hygiene methods used in a Vietnamese hospital. Am J Infect Control, 2014, 42(2): 178-181.
8. 周凤莲, 杨莉娜, 余阳, 等. 速干性手消毒剂对医院感染致病菌杀灭效果. 中国消毒学杂志, 2010, 27(6): 673-674.
9. 周凤莲, 杨莉娜, 余阳, 等. 常用消毒剂对部分多重耐药菌杀灭效果的观察. 中国消毒学杂志, 2013, 30(9): 808-810.
10. 李春梅, 钟晓祝, 杨金城. 葡萄糖酸氯己定醇皮肤消毒液对多药耐药菌的杀菌效果评价. 中华医院感染学杂志, 2013, 23(3): 610-611.

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