Analysis on multidrug-resistant organisms monitoring between 2013 and 2015 in a high-rank comprehensive hospital_West China Medical Journal

Authors：

LEI Xibing , HUANG Wei ,  CHEN Liping , TANG Yan , SUN Rui , TAN Muyang , XIAO Yaxiong

Nosocomial Infection Management Office, the First People’s Hospital of Yibin City, Yibin, Sichuan 644000, P. R. China;

Corresponding author：

CHEN Liping, Email: 1837639492@qq.com

Keywords：

Multidrug resistance; Detection rate; Distribution

DOI：

10.7507/1002-0179.201702115

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To investigate the detection of multidrug-resistant organisms (MDRO) by targeted monitoring in a tertiary hospital, and to understand the distribution of MDRO. Methods We retrospectively analyzed the detection and distribution of methicillin-resistantStaphylococcus aureus (MRSA), carbon black alkeneAcinetobacter baumannii (CRABA), carbapenem-resistantPseudomonas aeruginosa (CRPAE), vancomycin-resistantEnterococci (VRE) and carbapenem-resistantEnterobacter (CRE) in clinical samples collected from 2013 to 2015. Results A total of 990 multidrug-resistant bacteria strains were isolated from 2013 to 2015, of which 445 were MRSA (44.95%), 328 were CRABA (33.13%), 99 were CRPAE (10.00%), 12 were VRE (1.21%), and 106 were CRE (10.71%). They were mainly distributed in the Department of Burn, Comprehensive ICU, Department of Neurosurgery, Department of Respiratory Medicine and Department of Orthopedic Surgery. The detection rates of multidrug-resistant organisms of 2013-2015 were 10.85% (352/3 244), 9.20% (304/3 303), and 7.11% (334/4 699) respectively, which reduced year by year with significant difference (χ²= 34.42,P< 0.001). The detection rates of CRPAE, CRE and VRE all reduced with significant differences (P< 0.05). Conclusions The detection rate of multidrug-resistant organisms under targeted monitoring shows an obvious downward trend. MRSA and CRABA are still the major MDROs, which show no obvious change. The detection rates of CRPAE, VRE and CRE show obvious downward trend. Department of Burn, Comprehensive ICU, Department of Neurosurgery, Department of Respiratory Medicine and Department of Orthopedic Surgery have the highest risks of MDRO. In the future, we should strengthen the monitoring of high-risk departments, and focus on the reasonable choice of special antimicrobial agents to avoid special MDROs.

Citation： LEI Xibing, HUANG Wei, CHEN Liping, TANG Yan, SUN Rui, TAN Muyang, XIAO Yaxiong. Analysis on multidrug-resistant organisms monitoring between 2013 and 2015 in a high-rank comprehensive hospital. West China Medical Journal, 2017, 32(3): 334-338. doi: 10.7507/1002-0179.201702115 Copy

1.	熊亚南, 刘颖. 细菌耐药现状及抗菌药物研究进展. 中华医学信息导报, 2016, 31(8): 16.
2.	张禹. 合理使用抗生素刻不容缓. 家庭医药, 2016(4): 40-41.
3.	陈家敏, 李新. 某院 2013 年院内感染临床耐药情况的监测报告. 中国医药指南, 2014(36): 376-378.
4.	张雅薇, 王辉. 2015 年 CLSI M100-S25 主要更新内容介绍. 中华检验医学杂志, 2015, 38(4): 229-232.
5.	张静, 喻玮, 赵丽娜, 等. 我国细菌耐药现状与特征. 中华临床感染病杂志, 2016, 9(2): 118-128.
6.	王晓川, 郝雪龚, 大洁. “超级细菌”简介. 生物学教学, 2016, 41(9): 58-58, 59.
7.	Pal C, Bengtsson-Palme J, Kristiansson E,et al. The structure and diversity of human, animal and environmental resistomes. Microbiome, 2016, 4(1): 54.
8.	王金荣, 高攀, 崔朝勃, 等. 某院重症医学科 2010–2013 年鲍曼不动杆菌耐药性监测. 中国感染控制杂志, 2016, 15(2): 108-110.
9.	孙吉花, 张学美, 邢敏, 等. 山东省多中心 ICU 多药耐药菌目标性监测分析. 中华医院感染学杂志, 2016, 26(11): 2465-2467, 2616.
10.	陈晓娟, 任琳洁, 黄建琼. 根因分析在烧伤层流病房多重耐药菌管理中的应用. 华西医学, 2016, 31(8): 1413-1415.
11.	陈佰义, 何礼贤, 胡必杰, 等. 中国鲍曼不动杆菌感染诊治与防控专家共识. 中国医药科学, 2012, 2(8): 3-8.
12.	雷曦兵, 陈丽萍, 肖亚雄. 某三级甲等医院实施多重耐药防控干预效果研究. 华西医学, 2016, 31(3): 409-413.
13.	李露池, 沈晖. 某三级综合医院多重耐药菌临床分布. 中国感染控制杂志, 2014, 13(4): 242-245.
14.	王盟. 2012 至 2014 年某三级综合医院住院患者多药耐药菌感染分析. 中华实验和临床感染病杂志: 电子版, 2016, 10(3): 333-336.
15.	国家卫生计生委合理用药专家委员会, 全国细菌耐药监测网. 2015 年全国细菌耐药监测报告. 中国执业药师, 2016, 3(13): 3-8.
16.	李耘, 吕媛, 薛峰, 等. 中国细菌耐药监测研究 2013 至 2014 年非发酵革兰阴性菌监测报告. 中华检验医学杂志, 2016, 39(2): 130-138.

1. 熊亚南, 刘颖. 细菌耐药现状及抗菌药物研究进展. 中华医学信息导报, 2016, 31(8): 16.
2. 张禹. 合理使用抗生素刻不容缓. 家庭医药, 2016(4): 40-41.
3. 陈家敏, 李新. 某院 2013 年院内感染临床耐药情况的监测报告. 中国医药指南, 2014(36): 376-378.
4. 张雅薇, 王辉. 2015 年 CLSI M100-S25 主要更新内容介绍. 中华检验医学杂志, 2015, 38(4): 229-232.
5. 张静, 喻玮, 赵丽娜, 等. 我国细菌耐药现状与特征. 中华临床感染病杂志, 2016, 9(2): 118-128.
6. 王晓川, 郝雪龚, 大洁. “超级细菌”简介. 生物学教学, 2016, 41(9): 58-58, 59.
7. Pal C, Bengtsson-Palme J, Kristiansson E,et al. The structure and diversity of human, animal and environmental resistomes. Microbiome, 2016, 4(1): 54.
8. 王金荣, 高攀, 崔朝勃, 等. 某院重症医学科 2010–2013 年鲍曼不动杆菌耐药性监测. 中国感染控制杂志, 2016, 15(2): 108-110.
9. 孙吉花, 张学美, 邢敏, 等. 山东省多中心 ICU 多药耐药菌目标性监测分析. 中华医院感染学杂志, 2016, 26(11): 2465-2467, 2616.
10. 陈晓娟, 任琳洁, 黄建琼. 根因分析在烧伤层流病房多重耐药菌管理中的应用. 华西医学, 2016, 31(8): 1413-1415.
11. 陈佰义, 何礼贤, 胡必杰, 等. 中国鲍曼不动杆菌感染诊治与防控专家共识. 中国医药科学, 2012, 2(8): 3-8.
12. 雷曦兵, 陈丽萍, 肖亚雄. 某三级甲等医院实施多重耐药防控干预效果研究. 华西医学, 2016, 31(3): 409-413.
13. 李露池, 沈晖. 某三级综合医院多重耐药菌临床分布. 中国感染控制杂志, 2014, 13(4): 242-245.
14. 王盟. 2012 至 2014 年某三级综合医院住院患者多药耐药菌感染分析. 中华实验和临床感染病杂志: 电子版, 2016, 10(3): 333-336.
15. 国家卫生计生委合理用药专家委员会, 全国细菌耐药监测网. 2015 年全国细菌耐药监测报告. 中国执业药师, 2016, 3(13): 3-8.
16. 李耘, 吕媛, 薛峰, 等. 中国细菌耐药监测研究 2013 至 2014 年非发酵革兰阴性菌监测报告. 中华检验医学杂志, 2016, 39(2): 130-138.

West China Medical Journal

Analysis on multidrug-resistant organisms monitoring between 2013 and 2015 in a high-rank comprehensive hospital

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content