• 1. Department of Cardiology, Chengdu Shangjinnanfu Hospital, Chengdu, Sichuan 611730, P. R. China;
  • 2. Department of Cardiology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;
  • 3. Emergency Department, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;
WAN Zhi, Email: 456wz@163.com
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Objective  To investigate the correlation between plasma aminoterminal pro-B-type natriuretic peptide (NT-proBNP) level and severity of coronary artery lesions in patients with non-ST segment elevation myocardial infarction (NSTEMI). Methods  NSTEMI patients presenting to the Emergency Department and Department of Cardiology from January 2013 to March 2017 were divided into four groups: thrombosis without stenosis, single vessel disease, double vessel diseases, and three vessel diseases. The general situation of the patients, the plasma NT-proBNP, troponin T, echocardiogram and coronary angiography results were analyzed. Results  A total of 88 patients were included including 6 in thrombosis without stenosis group, 20 in single vessel disease group, 31 in double vessel diseases group, and 31 in three vessel diseases group. The NT-proBNP level, left ventricular ejection fraction, left ventricular end diastolic diameter, and coronary Gensini score in three vessel diseases group differed much from those in the other groups (P<0.05). The correlation of NT-proBNP with coronary Gensini score in all the patients was positve (t=0.663, P<0.05). Conclusion  The level of plasma NT-proBNP in patients with NSTEMI is related to the severity of coronary artery disease.

Citation: WANG Lin, HE Yue, WEI Wei, WAN Zhi. Correlation between plasma aminoterminal pro-B-type natriuretic peptide level and severity of coronary artery lesions in patients with non-ST segment elevation myocardial infarction. West China Medical Journal, 2017, 32(6): 804-807. doi: 10.7507/1002-0179.201705104 Copy

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