Development from empirical medicine to precision medicine: interpretation of Diagnosis for Pulmonary Tuberculosis (WS 288-2017)_West China Medical Journal

Authors：

CHEN Xuerong ¹ ,  CHEN Xiaoyou ²

1. Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;
2. Tuberculosis Medicine Ⅲ Department, Beijing Chest Hospital, Capital Medical University; Bejing Tuberculosis and Thoracic Tumor Institute; Beijing 101149, P. R. China;

Corresponding author：

CHEN Xiaoyou, Email: chenxy1998@hotmail.com

Keywords：

Pulmonary tuberculosis; Diagnostic standard; Precision medicine

DOI：

10.7507/1002-0179.201807076

Video：

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Basing on development of medical model, new national diagnostic standard is interpreted according to three aspects: classification, diagnostic standard, and diagnostic contents. Tracheobronchial tuberculosis and tuberculous pleurisy are added into the classification. The value of molecular and pathological techniques for diagnosis of the pulmonary tuberculosis is emphasized. The status of drug-resistance is included in the diagnostic content. Two opinions are suggested: some practical methods such as diagnostic chemotherapy are indicated in some grassroots areas, while new molecular techniques for detection of DNA/RNA of mycobacteria and resistant mutation are encouraged in some suitable institutions.

Citation： CHEN Xuerong, CHEN Xiaoyou. Development from empirical medicine to precision medicine: interpretation of Diagnosis for Pulmonary Tuberculosis (WS 288-2017). West China Medical Journal, 2018, 33(8): 950-952. doi: 10.7507/1002-0179.201807076 Copy

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12.	Conde MB, Loivos AC, Rezende VM, et al. Yield of sputum induction in the diagnosis of pleural tuberculosis. Am J Resp Crit Care Med, 2003, 167(5): 723.
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1. 中华人民共和国国家卫生和计划生育委员会. 肺结核诊断: WS 288－2017. (2017-11-09)[2018-06-01]. http://www.nhfpc.gov.cn/ ewebeditor/uploadfile/2017/12/20171212154852389.pdf.
2. 中华人民共和国国家卫生和计划生育委员会. 结核病分类: WS 196－2017. (2017-11-09)[2018-06-01]. http://www.nhfpc.gov.cn/ ewebeditor/uploadfile/2017/12/20171212154717348.pdf.
3. 刘毅, 张旭霞, 张雨晴, 等. 结核分枝杆菌三种蛋白在结核病血清学诊断中的评价研究. 中国防痨杂志, 2017, 39(8): 815-820.
4. Xiao JN, Xiong Y, Chen Y, et al. Determination of lipoprotein Z-specific IgA in tuberculosis and latent tuberculosis infection. Front Cell Infect Microbiol, 2017, 7(7): 495.
5. 李为民, 刘伦旭. 呼吸系统疾病的基础与临床. 北京: 人民卫生出版社, 2017.
6. World Health Organization. Global tuberculosis report 2017: WHO/HTM/TB/2017.23. Geneva: World Health Organization, 2017. http://www.who.int/tb/publications/global_report/en/.
7. Dorman SE, Schumacher SG, Alland D, et al. Xpert MTB/RIF ultra for detection of mycobacterium tuberculosis and rifampicin resistance: a prospective multicentre diagnostic accuracy study. Lancet Infect Dis, 2018, 18(1): 76-84.
8. Ou X, Li Q, Xia H, et al. Diagnostic accuracy of the PURE-LAMP test for pulmonary tuberculosis at the county-level laboratory in China. PLoS One, 2014, 9(5): e94544.
9. Gui X, Xiao H. Diagnosis of tuberculosis pleurisy with adenosine deaminase (ADA): a systematic review and meta-analysis. Int J Clin Exp Med, 2014, 7(10): 3126-3135.
10. Kim HJ, Lee HJ, Kwon SY, et al. The prevalence of pulmonary parenchymal tuberculosis in patients with tuberculous pleuritis. Chest, 2006, 129(5): 1253-1258.
11. Udwadia ZF, Sen T. Pleural tuberculosis: an update. Curr Opin Pulm Med, 2010, 16(16): 399-406.
12. Conde MB, Loivos AC, Rezende VM, et al. Yield of sputum induction in the diagnosis of pleural tuberculosis. Am J Resp Crit Care Med, 2003, 167(5): 723.
13. Klimiuk J, Krenke R, Safianowska A, et al. Diagnostic performance of different pleural fluid biomarkers in tuberculous pleurisy. Adv Exp Med Biol, 2015, 852: 21-30.
14. Jiang F, Huang W, Wang Y, et al. Nucleic acid amplification testing and sequencing combined with acid-fast staining in needle biopsy lung tissues for the diagnosis of smear-negative pulmonary tuberculosis. PLoS One, 2016, 11(12): e0167342.

West China Medical Journal

Development from empirical medicine to precision medicine: interpretation of Diagnosis for Pulmonary Tuberculosis (WS 288-2017)

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