Level of blood pressure and hypertension prevalence and influencing factors in middle-aged population with positive family history of hypertension_West China Medical Journal

Authors：

WU Yu ^1,2 , ZHANG Yang ¹ , TANG Weiwei ³ ,  HUANG Xiaobo ¹ , LIU Jianxiong ¹ , LIU Ya ⁴ , HU Yongmei ¹ , NIE Xiaoli ¹ , LI Qiu ¹ , OUYANG Lingyun ⁴

1. Department of Cardiology, Chengdu Second People’s Hospital, Chengdu, Sichuan 610017, P. R. China;
2. Department of Cardiology, People’s Hospital of the Central District of Leshan, Leshan, Sichuan 614000, P. R. China;
3. School of Health Policy & Management, Nanjing Medical University, Nanjing, Jiangsu 211166, P. R. China;
4. Department of Endocrinology, Chengdu Second People’s Hospital, Chengdu, Sichuan 610017, P. R. China;

Corresponding author：

HUANG Xiaobo, Email: drhuangxiaobo@126.com

Keywords：

Positive family history of hypertension; Hypertension; Prevalence; Risk factors

DOI：

10.7507/1002-0179.201902013

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Objective To investigate the blood pressure level and prevalence of hypertension in middle-aged people with positive family history of hypertension in Chengdu area, compare the differences between middle-aged people with positive family history of hypertension and middle-aged people with negative family history of hypertension, and explore the influencing factors of hypertension in middle-aged people with positive family history of hypertension.Methods From September 2013 to March 2014, the stratified sampling method was used to survey 3 096 middle-aged people aged 40-59 years in Chengdu. Their height, weight, blood pressure, blood glucose, and blood lipids were measured. Questionnaire surveys were conducted using a uniformly designed questionnaire. The blood pressure levels and hypertension prevalences were compared between people with and without positive family history of hypertension. The influencing factors of hypertension in middle-aged people with positive family history of hypertension were analyzed using multiple logistic regression.Results There were significant differences between the middle-aged people with positive family history of hypertension and the ones with negative family history of hypertension in systolic blood pressure [(137.4±22.4) vs. (118.0±11.3) mm Hg (1 mm Hg=0.133 kPa), P<0.001], diastolic blood pressure [(84.1±12.2) vs. (73.9±7.7) mm Hg, P<0.001], and prevalence of hypertension (28.6% vs. 22.2%, P<0.001). Ageing [odds ratio (OR)=1.107, 95% confidence interval (CI) (1.071, 1.144), P<0.001], monthly personal income ≥3 000 yuan [OR=1.566, 95%CI (1.003, 2.445), P=0.048], and abdominal obesity [OR=1.658, 95%CI (1.091, 2.520), P=0.018] were the risk factors for hypertension in middle-aged males with positive family history. Ageing [OR=2.257, 95%CI (1.202, 4.025), P=0.026] and overweight or obesity [OR=2.365, 95%CI (1.653, 3.385), P<0.001] were the risk factors, and physical exercise [OR=0.529, 95%CI (0.304, 0.918), P=0.024] was the protective factor for hypertension in middle-aged females with positive family history.Conclusions The prevalence of hypertension is high in middle-aged population with positive family history of hypertension in Chengdu and is significantly higher than that in the ones with negative family history of hypertension. Strengthening health education on hypertension-related knowledge, and reasonably controlling waist circumference and body weight may have positive significance in preventing or delaying the occurrence of hypertension in people with positive family history of hypertension.

Citation： WU Yu, ZHANG Yang, TANG Weiwei, HUANG Xiaobo, LIU Jianxiong, LIU Ya, HU Yongmei, NIE Xiaoli, LI Qiu, OUYANG Lingyun. Level of blood pressure and hypertension prevalence and influencing factors in middle-aged population with positive family history of hypertension. West China Medical Journal, 2019, 34(9): 1022-1027. doi: 10.7507/1002-0179.201902013 Copy

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9.	Huang XB, Tang WW, Liu Y, et al. Prevalence of diabetes and unrecognized diabetes in hypertensive patients aged 40 to 79 years in southwest China. PLoS One, 2017, 12(2): e0170250.
10.	黄广勇, 顾东风, 吴锡桂, 等. 父母高血压史对子女高血压患病率及血压水平的影响. 高血压杂志, 2002, 10(3): 274-277.
11.	吴小艳, 李强, 严惠, 等. 陕西省汉中市农村居民高血压与家族史的相关性分析. 中华流行病学杂志, 2017, 38(8): 1050-1054.
12.	黄晓波, 胡蓉, 乐庆荣, 等. 重庆市城乡居民高血压患病及影响因素分析. 中国公共卫生, 2009, 25(1): 25-27.
13.	Li T, Xian Y, Mao HM, et al. Prevalence, awareness, treatment and control of high blood pressure among Chinese rural population in Haimen, Jiangsu. J Hum Hypertens, 2016, 30(4): 225-230.
14.	Huang XB, Chen F, Dai W, et al. Prevalence and risk factors associated with hypertension in the Chinese Qiang population. Clin Exp Hypertens, 2018, 40(5): 427-433.
15.	冯超, 张卫东, 孙荣国, 等. 1355例公务员超重肥胖及其与高血压的相关性分析. 华西医学, 2008, 23(3): 542-543.

1. Kearney PM, Whelton M, Reynolds K, et al. Global burden of hypertension: analysis of worldwide data. Lancet, 2005, 365(9455): 217-223.
2. Wang Z, Chen Z, Zhang L, et al. Status of hypertension in China: results from the China Hypertension Survey, 2012-2015. Circulation, 2018, 137(22): 2344-2356.
3. 中国高血压防治指南修订委员会. 中国高血压防治指南2010. 中华高血压杂志, 2011, 19(8): 701-743.
4. 中国肥胖问题工作组数据汇总分析协作组. 我国成人体重指数和腰围对相关疾病危险因素异常的预测价值: 适宜体重指数和腰围切点的研究. 中华流行病学杂志, 2002, 23(1): 5-10.
5. 中国成人血脂异常防治指南修订联合委员会. 中国成人血脂异常防治指南(2016年修订版). 中国循环杂志, 2016, 31(10): 937-950.
6. Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care, 2003, 26(Suppl 1): S5-S20.
7. 刘东霞, 华琦, 郭金成, 等. 有家族史与无家族史高血压病患者发病特点及危险因素的调查分析. 心肺血管病杂志, 2006, 25(2): 71-74.
8. 中国医师协会肾脏内科医师分会. 中国肾脏疾病高尿酸血症诊治的实践指南(2017版). 中华医学杂志, 2017, 97(25): 1927-1936.
9. Huang XB, Tang WW, Liu Y, et al. Prevalence of diabetes and unrecognized diabetes in hypertensive patients aged 40 to 79 years in southwest China. PLoS One, 2017, 12(2): e0170250.
10. 黄广勇, 顾东风, 吴锡桂, 等. 父母高血压史对子女高血压患病率及血压水平的影响. 高血压杂志, 2002, 10(3): 274-277.
11. 吴小艳, 李强, 严惠, 等. 陕西省汉中市农村居民高血压与家族史的相关性分析. 中华流行病学杂志, 2017, 38(8): 1050-1054.
12. 黄晓波, 胡蓉, 乐庆荣, 等. 重庆市城乡居民高血压患病及影响因素分析. 中国公共卫生, 2009, 25(1): 25-27.
13. Li T, Xian Y, Mao HM, et al. Prevalence, awareness, treatment and control of high blood pressure among Chinese rural population in Haimen, Jiangsu. J Hum Hypertens, 2016, 30(4): 225-230.
14. Huang XB, Chen F, Dai W, et al. Prevalence and risk factors associated with hypertension in the Chinese Qiang population. Clin Exp Hypertens, 2018, 40(5): 427-433.
15. 冯超, 张卫东, 孙荣国, 等. 1355例公务员超重肥胖及其与高血压的相关性分析. 华西医学, 2008, 23(3): 542-543.

West China Medical Journal

Level of blood pressure and hypertension prevalence and influencing factors in middle-aged population with positive family history of hypertension

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