Operation process of alveolar lavage for patients with coronavirus disease 2019 in West China Hospital of Sichuan University_West China Medical Journal

Authors：

YANG Yiyi , WANG Bo , LIU Tingting , YANG Lan , WANG Peng , DONG Meiling , XUE Yang , YANG Yunqin , CHEN Baixu , LI Wei , XIA Wenxi ,  JING Xiaodong

Department of Intensive Care Unit, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, P. R. China;

Corresponding author：

JING Xiaodong, Email: zh_jxd@163.com

Keywords：

Severe acute respiratory syndrome coronavirus 2; Coronavirus disease 2019; Alveolar lavage

DOI：

10.7507/1002-0179.202003365

Video：

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For patients with suspected or confirmed coronavirus disease 2019, how to take lavage fluid specimens correctly is the current clinical focus during the epidemic. At the same time, since alveolar lavage is an invasive operation of the airway, it is necessary to follow standard procedures for protection and operation to prevent occupational exposure risks of medical staff. The Department of Intensive Care Unit of West China Hospital of Sichuan University formulated the operation procedure of alveolar lavage for patients with coronavirus disease 2019 based on the original operation procedure of alveolar lavage. This article introduces the indications and contraindications of the operation procedure, preparation before operation, operation procedure and precautions, post-operation processing and operation protection for clinical reference and implementation.

Citation： YANG Yiyi, WANG Bo, LIU Tingting, YANG Lan, WANG Peng, DONG Meiling, XUE Yang, YANG Yunqin, CHEN Baixu, LI Wei, XIA Wenxi, JING Xiaodong. Operation process of alveolar lavage for patients with coronavirus disease 2019 in West China Hospital of Sichuan University. West China Medical Journal, 2020, 35(11): 1285-1289. doi: 10.7507/1002-0179.202003365 Copy

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1. 国家卫生健康委办公厅, 国家中医药管理局办公室. 新型冠状病毒肺炎诊疗方案(试行第七版). (2020-03-03)[2020-03-21]. http://www.nhc.gov.cn/yzygj/s7653p/202003/46c9294a7dfe4cef80dc7f5912eb1989.shtml.
2. 施绍瑞, 聂滨, 郭渝, 等. 新型冠状病毒肺炎病例多种生物样本的病毒核酸检测结果. 华西医学, 2020, 35(2): 132-136.
3. 武汉同济医院新型冠状病毒肺炎救治协作组. 重症新型冠状病毒感染肺炎诊疗与管理共识. (2020-02-09)[2020-03-21]. https://www.tjh.com.cn/plmnhytf12f3/1/1111/2020/fyzl/%E6%8C%87%E5%8D%97.PDF.
4. 吴东波, 陈恩强, 王丽春, 等. 四川大学华西医院隔离病房新型冠状病毒肺炎患者的诊治. 华西医学, 2020, 35(5): 513-518.
5. 中华医学会呼吸病学分会. 肺部感染性疾病支气管肺泡灌洗病原体检测中国专家共识(2017 年版). 中华结核和呼吸杂志, 2017, 40(8): 578-583.
6. Bradley B, Branley HM, Egan JJ, et al. Interstitial lung disease guideline: the British Thoracic Society in collaboration with the Thoracic Society of Australia and New Zealand and the Irish Thoracic Society. Thorax, 2008, 63(Suppl 5): v1-v58.
7. Drieghe S, Ryckaert I, Beuselinck K, et al. Epidemiology of respiratory viruses in bronchoalveolar lavage samples in a tertiary hospital. J Clin Virol, 2014, 59(3): 208-211.
8. 中华医学会呼吸病学分会. 诊断性可弯曲支气管镜应用指南(2008 年版). 中华结核和呼吸杂志, 2008, 31(1): 14-17.
9. Baughman RP. Technical aspects of bronchoalveolar lavage: recommendations for a standard procedure. Semin Respir Crit Care Med, 2007, 28(5): 475-485.
10. Meyer KC. Bronchoalveolar lavage as a diagnostic tool. Semin Respir Crit Care Med, 2007, 28(5): 546-560.
11. Pingleton SK, Harrison GF, Stechschulte DJ, et al. Effect of location, pH, and temperature of instillate in bronchoalveolar lavage in normal volunteers. Am Rev Respir Dis, 1983, 128(6): 1035-1037.
12. 国家卫生健康委办公厅. 关于印发医疗机构内新型冠状病毒感染预防与控制技术指南(第一版)的通知. (2020-01-23)[2020-03-21]. http://www.nhc.gov.cn/yzygj/s7659/202001/b91fdab7c304431eb082d67847d27e14.shtml.
13. 国家卫生和计划生育委员会办公厅. 人感染 H7N9 禽流感医院感染预防与控制技术指南(2013 年版). (2013-04-03)[2020-03-21]. http://www.nhc.gov.cn/yzygj/s3593g/201304/80c91e33675e4c04ae023c3dfc674099.shtml.
14. 中华医学会呼吸病学分会呼吸治疗学组. 新型冠状病毒感染重型及危重型患者呼吸治疗相关操作防护措施专家共识. 中华结核和呼吸杂志. (2020-02-20)[2020-03-21]. http://rs.yiigle.com/yufabiao/1182334.htm.
15. 国家卫生健康委办公厅. 国家卫生健康委办公厅关于印发新型冠状病毒感染的肺炎防控中常见医用防护用品使用范围指引(试行)的通知. (2020-01-27)[2020-03-21]. http://www.nhc.gov.cn/yzygj/s7659/202001/e71c5de925a64eafbe1ce790debab5c6.shtml.
16. 国家卫生健康委办公厅. 医院预防与控制传染性非典型肺炎(SARS)医院感染的技术指南. (2007-10-18)[2020-03-21]. http://www.nhc.gov.cn/yzygj/s3585/200804/93784e5fa14046c38fa71d7ddfd83c4b.shtml.

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Operation process of alveolar lavage for patients with coronavirus disease 2019 in West China Hospital of Sichuan University

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